scholarly journals Endoscopic submucosal dissection of large leiomyoma of the esophagus with subsequent closure of the defect with a mucosal flap

2019 ◽  
Vol 178 (2) ◽  
pp. 59-61
Author(s):  
A. A. Avanesyan ◽  
A. E. Akkalaeva ◽  
B. I. Miroshnikov ◽  
V. M. Moiseenko

Taking into consideration the results of our clinical observation, we can argue that the technique of endoscopic submucosal dissection of large leiomyoma of the esophagus with subsequent closure of the defect with a mucosal flap is applicable in clinical practice. This method is relatively safe, allows to achieve complete, quality results of morphological study, helps to reduce the number of postoperative complications, compared to more invasive surgical interventions. Also it reduces the time of social recovery and contributes to preserving the quality of life after the treatment.

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Liang Liu ◽  
Xingjie Shen ◽  
Jingyu Zhu

Purpose. Studies reporting the treatment of early colorectal cancer (ECC) by endoscopic submucosal dissection (ESD) in elderly patients are lacking in China. The aim was to evaluate the efficacy, safety and overall quality of life of elderly patients with ECC who undergoing ESD. Methods. Three hundred and seventy-nine patients with 401 colorectal lesions entered into our study from March 2013 to March 2016 (Patients with an age 70 years old or older were divided into the elderly group and those who were less than 70-year-old entered the non-elderly group). Results. No significant differences were found in sex ratio, body mass index, location, endoscopic classification, pathological pattern, lesion size, mean procedure time, hospitalization days, complete excision, and en bloc resection rate between the two groups (P>0.05). No significant differences were observed between the groups in terms of complications during and after ESD procedure (P>0.05). There were no statistical differences between two groups in Quality of life index (QL-Index) and European Organization for Research and Treatment quality of life version 3.0 questionnaire (EORTC QLQ-C30) scores (P>0.05). Conclusion. ESD was relatively safe and effective for elderly patients with ECC, and it may be an recommended first-line treatment.


2017 ◽  
Vol 41 (S1) ◽  
pp. S669-S669
Author(s):  
S. Lee ◽  
H. Lee ◽  
S.T. Oh ◽  
H.H. Jeon ◽  
W.J. Choi

IntroductionCancer patients may encounter psychological distress, change of emotional status, and lowered quality of life. It is predicted that similar changes will be shown during the Endoscopic Submucosal Dissection (ESD) of early stomach cancer. The objective of this study is to evaluate changes of emotional status and quality of life over time depending on baseline level of psychological distress.MethodNinety-seven patients indicated with ESD who visited National Health Insurance Service Ilsan Hospital in Korea between May 2015 and June 2016 were evaluated. Psychological distress, emotional status, and quality of life were evaluated at the day before ESD. Follow-up evaluations of them were done at the day after ESD, 2 and 10 weeks later.ResultThe group with high psychological distress showed higher female ratio, more depressive and anxiety symptoms than those of the group with low psychological distress. Psychological distress was related to stress level and lowered quality of life. Repeated measures ANOVA analysis showed that significant differences of depression (MADRS), anxiety (HAM-A), level of stress (GARS), and quality of life (EORTC QLQ-C30) were sustained over time, but the decreasing tendency of the differences between the groups was also noticed.ConclusionThe study revealed that patients who feel more psychological distress may experience more depressive and anxiety symptoms, increased level of stress, and lowered quality of life. We recommend screening of patients with early stomach cancer for psychological distress before ESD, which may improve subjective life satisfaction of patients during ESD.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2020 ◽  
pp. 3-25
Author(s):  
D. Lukanin ◽  
G. Rodoman ◽  
M. Klimenko ◽  
A. Sokolov ◽  
A. Sokolov

The article presents the results of a prospective controlled parallel clinical study of a new modification of laparoscopic antireflux surgery in the treatment of gastroesophageal reflux disease in combination with a hiatal hernia compared with laparoscopic Nissen fundoplication in terms of assessing quality of life after surgery. Clinical and instrumental examination of patients was carried out a year after surgical interventions. In accordance with the results of instrumental examination after surgery, the proposed modification of laparoscopic partial fundoplication is not inferior to laparoscopic Nissen fundoplication both, in terms of relief of reflux esophagitis symptoms and in relation to the recurrence of hiatal hernia. Clinical monitoring indicates a significantly higher quality of life for patients after the modified antireflux surgery, which is associated with a number of factors. The implementation of this fundoplication led to a decrease in the number of patients with complaints of dysphagia, the development of which is directly related to the surgery performance, as well as to a statistically significant reduction of bloating in the upper abdomen. Another advantage of the modified surgery is a significantly smaller number of cases of gas-bloat syndrome. In addition, the disorders developing in the framework of the gas bloat syndrome after laparoscopic Nissen fundoplication are more severe.


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