scholarly journals Önemli Tıbbi Bitkilerden Biri Olan Achillea millefolium L. (Civanperçemi) Bitkisinin Besin Elementi Konsantrasyonları ve Antioksidan Aktivitesi

2021 ◽  
Vol 9 (3) ◽  
pp. 590-594
Author(s):  
Handan Saraç ◽  
Hasan Durukan ◽  
Ahmet Demirbaş
Keyword(s):  
Oxidative Stress ◽  
Water Extract ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Achillea Millefolium ◽  
Nutrient Concentrations ◽  
Oxidative Stress Index ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

In this study, it was aimed to determine the nutrient concentrations and antioxidant activity of Achillea millefolium L. (Yarrow), which is known to have medicinal properties. For this purpose, macro and micronutrient concentrations, total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of water extract Yarrow plant, which is known to be collected from Divrigi district in Sivas province, were determined. The results have shown that the yarrow plant is sufficient in terms of some macro and micronutrient concentrations, and the nitrogen (N), phosphorus (P), potassium (K), calcium (Ca) and magnesium from macro elements, iron (Fe), zinc (Zn), manganese (Mn) and copper (Cu) from micro elements concentrations were determined as 1.01% N, 0.63% P, 2.43% K, 2.22% Ca, 0.70% Mg, 360.4 mg kg-1 Fe, 47.6 mg kg-1 Zn, 85.5 mg kg-1 Mn and 28.3 mg kg-1 Cu, respectively. It has been determined that its antioxidant potential is moderate. In addition, the plant’s oxidant capacity and oxidative stress index were found to be low.

scholarly journals Antioxidant and Oxidant Status of Endemic Helleborus vesicarius

2020 ◽  
Vol 8 (9) ◽  
pp. 2008-2010
Author(s):  
Falah Saleh Mohammed ◽  
Gülcan Çınar ◽  
Serap Sahin Yigit ◽  
Hasan Akgül ◽  
Muhittin Dogan
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Oxidative Stress Index ◽  
Aerial Parts ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

Plants are important antioxidant sources. In our study, total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) of endemic Helleborus vesicarius Aucher ex Boiss.were determined. The aerial parts of the plant samples were dried and extracted with ethanol (EtOH). TAS and TOS values of plant extract were determined using Rel Assay Diagnostics kits. As a result of the studies, the TAS value of H. vesicarius was determined 5.548±0.23, the TOS value was 13.778±0.119 and the OSI value was 0.249±0.009. In this context, the plant has been shown to have significant antioxidant potential.

Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis

2020 ◽  
pp. 1-8
Author(s):  
Hasan Haci Yeter ◽  
Berfu Korucu ◽  
Elif Burcu Bali ◽  
Ulver Derici
Keyword(s):  
Oxidative Stress ◽  
Vitamin D ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Vitamin D Analog ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

Abstract. Background: The pathophysiological basis of chronic kidney disease and its complications, including cardiovascular disease, are associated with chronic inflammation and oxidative stress. We investigated the effects of active vitamin D (calcitriol) and synthetic vitamin D analog (paricalcitol) on oxidative stress in hemodialysis patients. Methods: This cross-sectional study was composed of 83 patients with a minimum hemodialysis vintage of one year. Patients with a history of any infection, malignancy, and chronic inflammatory disease were excluded. Oxidative markers (total oxidant and antioxidant status) and inflammation markers (C-reactive protein and interleukin-6) were analyzed. Results: A total of 47% (39/83) patients were using active or analog vitamin D. Total antioxidant status was significantly higher in patients with using active or analog vitamin D than those who did not use (p = 0.006). Whereas, total oxidant status and oxidative stress index were significantly higher in patients with not using vitamin D when compared with the patients who were using vitamin D preparation (p = 0.005 and p = 0.004, respectively). On the other hand, total antioxidant status, total oxidant status, and oxidative stress index were similar between patients who used active vitamin D or vitamin D analog (p = 0.6; p = 0.4 and p = 0.7, respectively). Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease.

scholarly journals Relationship Between Oxidative Stress Parameters and Cystatin C Levels in Patients With Severe Preeclampsia

Medicina ◽  
2013 ◽  
Vol 49 (3) ◽  
pp. 19 ◽  
Author(s):  
Saban Yalcin ◽  
Turgay Ulas ◽  
Mehmet Eren ◽  
Harun Aydogan ◽  
Aysun Camuzcuoglu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cystatin C ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Oxidative Stress Index ◽  
Oxidative Stress Parameters ◽  
Total Antioxidant ◽  
Group 2 ◽  
Oxidant Status ◽  
Group 1

Background and Objective. Oxidative stress is believed to play a role in the development of preeclampsia (PE). It is known that an increased cystatin C level is also associated with PE. The aim of this study was to investigate the relationship between oxidative stress parameters and cystatin C levels in patients with severe PE. Material and Methods. Forty-four patients with severe PE and 40 healthy pregnant women were recruited for the study. All study subjects were divided into 2 groups: group 1 (n=44) consisted of patients with severe PE, and group 2 (n=40) included healthy pregnant subjects. Blood samples were obtained from all subjects in order to measure the cystatin C level, total antioxidant status, and total oxidant status. The oxidative stress index was calculated. Results. The group 1 had significantly higher cystatin C, total oxidant status, oxidative stress index levels and lower total antioxidant status level as compared with the group 2 (P=0.001, P<0.001, P<0.001, P=0.036, respectively). The serum cystatin C level was significantly correlated with the oxidative stress index (r=0.609, P<0.001). Conclusions. The present study demonstrated that both oxidative stress and cystatin C levels were increased in patients with PE, and the increased cystatin C levels seem to be a consequence of oxidative stress. Correspondence to

scholarly journals Enzymatic Oxidative Stress Indicators and Oxidative Stress Index in Patients of Leprosy

2018 ◽  
Vol 16 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Ishita Raka ◽  
Madhur Kant Rastogi ◽  
Pratik Gahalaut ◽  
Jaspreet Kaur ◽  
Nitin Mishra
Keyword(s):  
Oxidative Stress ◽  
Total Antioxidant Status ◽  
Significant Rise ◽  
Stress Index ◽  
Stress Indicators ◽  
Oxidative Stress Index ◽  
Total Antioxidant ◽  
Leprosy Patients ◽  
Oxidative Stress Indicators ◽  
And Oxidative Stress

Introduction: Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae. Oxidative stress caused by Reactive oxygen species (ROS) plays a crucial role in the pathogenesisis of leprosy.Objective: To measure the enzymatic oxidative stress indicators and oxidative stress index in patients of leprosy and compare them with healthy age & sex matched controls.Materials and Methods: In this prospective study 30 untreated leprosy patients were included in the study and matched with 60 healthy controls. Biochemistry estimation was done with blood samples and MDA (lipid peroxidation), Nitric oxide (NO), (SOD) Superoxide dismutase (antioxidant enzyme), total oxidant status (TOS), total antioxidant status(TAS) and oxidative stress index (OSI) were estimated.Results: Highly significant rise (p<0.0001) in serum MDA, NO, TOS and OSI was seen in leprosy patients when compared with controls with highly significant decline in SOD and TAS.Conclusion: The study confirms the oxidative stress in leprosy and suggests antioxidant therapy may be used as an adjuvant in the treatment of leprosy along with MDT.

scholarly journals Evaluation of oxidative stress in sheep infected with Psoroptes ovis using total antioxidant capacity, total oxidant status, and malondialdehyde level

2017 ◽  
Vol 61 (2) ◽  
pp. 197-201 ◽  
Author(s):  
Mustafa Sinan Aktas ◽  
Fatih Mehmet Kandemir ◽  
Akin Kirbas ◽  
Basak Hanedan ◽  
Mehmet Akif Aydin
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Stress Index ◽  
Total Oxidant Status ◽  
Psoroptes Ovis ◽  
Oxidative Stress Index ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

AbstractIntroduction:The study aimed at evaluating oxidative stress using malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) markers in sheep naturally infected withPsoroptes ovis(Acari).Material and Methods:The study was performed on 40 sheep divided into two equal groups: a healthy group (group I) and a group naturally infected withPsoroptes ovis(group II). The sera were obtained by centrifuging blood samples collected from the vena jugularis and serum MDA level changes in the samples were measured spectrophotometrically. Commercially available test kits were used for the measurement of TAC and TOS levels. The percentage ratio of TOS level to TAC level was accepted as OSI.Results:The serum malondialdehyde, total oxidant status levels, and oxidative stress index increased significantly (P < 0.01) in group II, while the serum total antioxidant capacity levels decreased significantly (P < 0.01) in this group. Negative correlations between total antioxidant capacity and total oxidant status and total antioxidant capacity and malondialdehyde, and a positive correlation between total oxidant status and malondialdehyde were found in infected sheep.Conclusion:The obtained results indicated the relationship between oxidant/antioxidant imbalance andPsoroptes ovisinfection in sheep. Their MDA, TAC, TOS, and OSI markers may be used to determine the oxidative stress in natural infections withPsoroptes ovis.

scholarly journals Oxidative Stress Status in Sera and Saliva of Type 2 Diabetic Iraqi Patients with and without Proliferative Diabetic Retinopathy

2019 ◽  
Vol 31 (3) ◽  
pp. 719-722
Author(s):  
Hathama Razooki Hasan ◽  
Nuha Nihad A. Aburahma ◽  
Abdul Kareem A. AL-Kazaz
Keyword(s):  
Oxidative Stress ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Antioxidant Status ◽  
Total Antioxidant Status ◽  
Stress Index ◽  
Total Antioxidant ◽  
Oxidant Status ◽  
And Oxidative Stress

The present study aimed to look for the differences in the oxidative stress status in sera and saliva samples of type 2 diabetic Iraqi patients with and without proliferative diabetic retinopathy. As well as to look for the possibility whether this status can be measured in saliva as an alternative sample to that of serum, hence to achieve that total oxidant status, total antioxidant status and oxidative stress index were measured in both sera and saliva samples of two groups of patients with type 2 diabetes mellitus and the healthy individuals. Upon the comparison between patients without proliferative diabetic retinopathy and the control sample the results showed presence of a significant increase (p < 0.05) of total oxidant status and oxidative stress index in sera and saliva samples, while there was a significant decrease (p < 0.05) in total antioxidant status of sera and saliva samples. Meanwhile when the comparison was done between patients with proliferative diabetic retinopathy and those without proliferative diabetic retinopathy, a significant increase (p < 0.05) in both salivary total oxidant status and oxidative stress index was observed with a significant decrease (p < 0.05) in sera and salivary total antioxidant status were found in the proliferative diabetic retinopathy patients group.

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