Blood Group O, Rhesus Factor Distribution and Relationship with Blood Pressure Indices

Author(s):  
Erigbali P. P. ◽  
Kiridi E. K. ◽  
Koikoibo W.
2004 ◽  
Vol 18 (5) ◽  
pp. 351-363 ◽  
Author(s):  
M T Robinson ◽  
T W Wilson ◽  
G A Nicholson ◽  
G A C Grell ◽  
C Etienne ◽  
...  

1984 ◽  
Vol 2 (4) ◽  
pp. 337-341 ◽  
Author(s):  
Lillian Gleiberman ◽  
Henry Gershowitz ◽  
Ernest Harburg ◽  
Anthony M. Schork
Keyword(s):  

1984 ◽  
Vol 2 (4) ◽  
pp. 337-341 ◽  
Author(s):  
Lillian Gleiberman ◽  
Henry Gershowitz ◽  
Ernest Harburg ◽  
Anthony M. Schork
Keyword(s):  

2021 ◽  
Vol 12 (1) ◽  
pp. 130-135
Author(s):  
Rawaa Hadi Shareef ◽  
Basim A. Abd ◽  
Zahraa Fathi Sharba

Obesity is considered as a public health problem that affects all age groups in the population. Genetic factors are considered as one of the non-modifiable risk factors, causing obesity. Hypertension is a chronic medical condition that is associated with vague symptoms. The ABO blood type is one of the fundamental genetic factors that can give important information for early detection of risky population. This study aimed to evaluate the impact of different blood groups on body mass index and blood pressure. The design of this study is a cross-sectional study, included 250 participants (144 males and 106 females), aged between 18-70 years were selected from the population of Al-Najaf Governorate, Iraq, through a period which extends from October 2019 to February 2020.  The blood groups were determined for each participant; blood pressure and body mass index were also measured. The results of a current study revealed that from this 250 participants there was 115 were obese person, 82 were overweight person, 51 were normal weight, and 2 were underweight persons. In the obese group, the blood group B has the highest percentage (45.2% ) followed by blood group A and O that were found to have the same percentage (22.6%), while the blood group AB has the lower percentage (9.6%). On the other hand, there was no significant relationship between hypertension and ABO blood groups.


BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Shun Li ◽  
C. M. Schooling

Abstract Background ABO blood group is associated with differences in lifespan, cardiovascular disease, and some cancers, for reasons which are incompletely understood. To gain sex-specific additional insight about potential mechanisms driving these common conditions for future interventions, we characterized associations of ABO blood group antigen across the phenotype sex-specifically. Methods We performed a phenome-wide association study (PheWAS) assessing the association of tag single nucleotide polymorphisms (SNPs) for ABO blood group antigens (O, B, A1, and A2) with 3873 phenotypes. Results The tag SNP for the O antigen was inversely associated with diseases of the circulatory system (particularly deep vein thrombosis (DVT)), total cholesterol, low-density lipoprotein cholesterol (LDL-C), and ovarian cancer, and positively associated with erythrocyte traits, leukocyte counts, diastolic blood pressure (DBP), and healthy body composition; the tag SNP for the A1 antigen tended to have associations in reverse to O. Stronger associations were more apparent for men than women for DVT, DBP, leukocyte traits, and some body composition traits, whereas larger effect sizes were found for women than men for some erythrocyte and lipid traits. Conclusion Blood group has a complex association with cardiovascular diseases and its major risk factors, including blood pressure and lipids, as well as with blood cell traits and body composition, with some differences by sex. Lower LDL-C may underlie some of the benefits of blood group O, but the complexity of associations with blood group antigen suggests overlooked drivers of common chronic diseases.


Rhesus incompatibility can pose a problem in pregnancy and cause obstetric failure in a handful of women. The Rhesus factor is a red blood cell surface antigen; and there are many antigen subtypes that make up the Rhesus blood group systems, of which the most commonly involved and most immunogenically associated with Rhesus isoimmunisation is the D antigen. The objective of this study is to determine the prevalence of Rhesus negativity and the foetomaternal outcomes at the Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria. This was a 5-year retrospective study conducted between 1st January, 2016 and 31st December, 2020 at our Obstetric Unit. Data were retrieved, entered into a pre-designed preformed and analyzed using SPSS version 25.0. Results were presented as mean and standard deviation for continuous variables and frequencies or percentages for categorical variables. Of the 4,571 pregnant women, 104 were Rhesus negative, giving a rate of 2.27%. The most common blood group among the women (53.8%) and their partners (84.6%) was the O blood group. Only 2 (1.9%) women were sensitised. Out of the 104 Rhesus negative women, 81 were unsensitised (77.9%) and received anti-D immunoglobulin. Majority of the babies had a good outcome, though 19 (18.2%) of them were admitted into the special care baby unit for various conditions. The incidence of Rhesus negative pregnancy in our study was 2.27%, and 1.9% of the women were sensitised. Prompt administration of anti-D immunoglobulin after sensitising events and post-delivery is key in the prevention of Rhesus isoimmunisation.


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