scholarly journals The reactivity of propyl esters of 2-(benzoylamino)(1-R-2-oxoindoline-3-ylidene) acetic acids

2019 ◽  
Vol 17 (2(66)) ◽  
pp. 33-37
Author(s):  
O. M. Svechnikova ◽  
S. V. Kolisnyk ◽  
O. F. Vynnyk ◽  
O. O. Altukhov ◽  
T. A. Kostina
Keyword(s):  
1983 ◽  
Vol 14 (41) ◽  
Author(s):  
O. L. MNDZHOYAN ◽  
A. A. GAMBURGYAN ◽  
A. U. ISAKHANYAN ◽  
S. S. VASILYAN ◽  
A. V. POGOSYAN ◽  
...  

1973 ◽  
Vol 51 (11) ◽  
pp. 790-797 ◽  
Author(s):  
J. M. Godfraind ◽  
K. Krnjević ◽  
H. Maretić ◽  
R. Pumain

Systematic tests of imidazole and 15 derivatives, applied by microiontophoresis in anesthetized cats, showed a high inhibitory potency of imidazole-4-acetic and imidazole-4-propionic acids and also of their amyl and propyl esters; but imidazole 4-carboxylic and 1-methylimidazole-4-acetic acids were largely inactive. This order of potency is very different from the relative potencies of imidazole derivatives in facilitating cyclic nucleotide phosphodiesterase activity. It is therefore unlikely that their inhibitory action is simply related to changes in cellular levels of cyclic AMP. The characteristics of this action, including lack of antagonism by bicuculline, are consistent with the possibility that it is mediated by γ-aminobutyric acid receptors.


Author(s):  
Al W. Stinson

The stratified squamous epithelium which lines the ruminal compartment of the bovine stomach performs at least three important functions. (1) The upper keratinized layer forms a protective shield against the rough, fibrous, constantly moving ingesta. (2) It is an organ of absorption since a number of substances are absorbed directly through the epithelium. These include short chain fatty acids, potassium, sodium and chloride ions, water, and many others. (3) The cells of the deeper layers metabolize butyric acid and to a lesser extent propionic and acetic acids which are the fermentation products of rumen digestion. Because of the functional characteristics, this epithelium is important in the digestive process of ruminant species which convert large quantities of rough, fibrous feed into energy.Tissue used in this study was obtained by biopsy through a rumen fistula from clinically healthy, yearling holstein steers. The animals had been fed a typical diet of hay and grain and the ruminal papillae were fully developed. The tissue was immediately immersed in 1% osmium tetroxide buffered to a pH of 7.4 and fixed for 2 hrs. The tissue blocks were embedded in Vestapol-W, sectioned with a Porter-Blum microtome with glass knives and stained with lead hydroxide. The sections were studied with an RCA EMU 3F electron microscope.


2018 ◽  
Author(s):  
Patrick Moon ◽  
Zhongyu Wie ◽  
Rylan Lundgren

The stability and wide availability of carboxylic acids make them valuable reagents in chemical synthesis. Most transition metal catalyzed processes using carboxylic acid substrates are initiated by a decarboxylation event that generates reactive carbanion or radical intermediates. Developing enantioselective methodologies relying on these principles can be challenging, as highly reactive species tend to react indiscriminately without selectivity. Furthermore, anionic or radical intermediates generated from decarboxylation can be incompatible with protic and electrophilic functionality, or groups that undergo trapping with radicals. We demonstrate that metal-catalyzed enantioselective benzylation reactions of allylic electrophiles can occur directly from aryl acetic acids. The reaction proceeds via a pathway in which decarboxylation is the terminal event, occurring after stereoselective carbon–carbon bond formation. The mechanistic features of the process enable enantioselective benzylation without the generation of a highly basic nucleophile. Thus, the process has broad functional group compatibility that would not be possible employing established protocols.<br>


Rhizosphere ◽  
2019 ◽  
Vol 12 ◽  
pp. 100170 ◽  
Author(s):  
Muhammad Zahid Mumtaz ◽  
Karen M. Barry ◽  
Anthony L. Baker ◽  
David S. Nichols ◽  
Maqshoof Ahmad ◽  
...  

Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 139
Author(s):  
Natalia Aparicio-García ◽  
Cristina Martínez-Villaluenga ◽  
Juana Frias ◽  
Elena Peñas

This study investigates the use of sprouted oat flour as a substrate to develop a novel gluten-free beverage by fermentation with a probiotic (Lactobacillus plantarum WCFS1) starter culture. Physicochemical, microbiological, nutritional and sensory properties of sprouted oat fermented beverage (SOFB) were characterized. After fermentation for 4 h, SOFB exhibited an acidity of 0.42 g lactic acid/100 mL, contents of lactic and acetic acids of 1.6 and 0.09 g/L, respectively, and high viable counts of probiotic starter culture (8.9 Log CFU/mL). Furthermore, SOFB was a good source of protein (1.7 g/100 mL), β-glucan (79 mg/100 mL), thiamine (676 μg/100 mL), riboflavin (28.1 μg/100 mL) and phenolic compounds (61.4 mg GAE/100 mL), and had a high antioxidant potential (164.3 mg TE/100 mL). Spoilage and pathogenic microorganisms were not detected in SOFB. The sensory attributes evaluated received scores higher than 6 in a 9-point hedonic scale, indicating that SOFB was well accepted by panelists. Storage of SOFB at 4 °C for 20 days maintained L. plantarum viability and a good microbial quality and did not substantially affect β-glucan content. SOFB fulfils current consumer demands regarding natural and wholesome plant-based foods.


1995 ◽  
Vol 50 (1-2) ◽  
pp. 123-126 ◽  
Author(s):  
Gottfried Raab ◽  
Jürgen Jacob

Abstract The uropygial gland waxes of the South American red-legged Seriema (Cariama cristata (L., 1766)) were found to be composed of unbranched alcohols and 2,2′-dialkyl-substituted acetic acids which so far have not been found in skin lipids. When used as a chemosystematic character, the occurrence of this lipid class separates the order Cariamiformes (Seriemas) from all other avian orders hitherto investigated, especially from the Gruiformes (cranes and rails) to which they have been tentatively attributed in the past. From the GC retention time data now available for a series of 2-alkyl-substituted fatty acid methyl esters relative retention time indices for other compounds may be predicted.


Sign in / Sign up

Export Citation Format

Share Document