scholarly journals Application of Complementary Split Ring Resonator for Hyperthermia

2021 ◽  
Vol 13 (1) ◽  
pp. 34-40
Author(s):  
Rahmawati Yusri ◽  
Muldarisnur Muldarisnur

One of the most promising research for cancer therapy with less side effects is hyperthermia treatment using metamaterial. This treatment may stand independently or adjunct to other cancer treatments such as chemotherapy, radiotherapy, and others. Metamaterial may control the heating process needed and also the depth of metamaterial itself from the skin surface. In this simulation, complementary split-ring resonator (cSRR) metamaterial with gaps from 0.5 to 3.5 mm can be used for the hyperthermia treatment. In the simulation of the cSRR metamaterial as hyperthermia therapy for cancer cells, the heat generated from each cSRR model was not significantly different. All cSRR models can reach hyperthermal temperatures under 5 minutes. The highest temperature achievement after 60 minutes can be seen in the use of single gap cSRR (58.9 ℃), dual gaps cSRR (58.1 oC), triple gaps cSRR (57.5 ℃), and quad gaps cSRR (57.2 ℃). The cSRR metamaterial structure can be used for hyperthermia therapy by adjusting the treatment duration treatment on cancer cells.

Chemosensors ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 184
Author(s):  
Tomislav Markovic ◽  
Gertjan Maenhout ◽  
Matko Martinic ◽  
Bart Nauwelaers

This work presents the design and evaluation of a planar device for microwave heating of liquids in continuous microfluidics (CMF) made in polydimethylsiloxane (PDMS). It deals with volumes in the µL range, which are of high interest and relevance to biologists and chemists. The planar heater in this work is conceived around a complementary split-ring resonator (CSRR) topology that offers a desired electric field direction to—and interaction with—liquids in a microwell. The designed device on a 0.25 mm thick Rogers RO4350B substrate operates at around 2.5 GHz, while a CMF channel and a 2.45 µL microwell are manufactured in PDMS using the casting process. The evaluation of the performance of the designed heater is conducted using a fluorescent dye, Rhodamine B, dissolved in deionized water. Heating measurements are carried out using 1 W of power and the designed device achieves a temperature of 47 °C on a sample volume of 2.45 µL after 20 s of heating. Based on the achieved results, the CSRR topology has a large potential in microwave heating, in addition to the already demonstrated potential in microwave dielectric sensing, all proving the multifunctionality and reusability of single planar microwave-microfluidic devices.


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