scholarly journals Distinguishing Features: Staphylococcal Scalded Skin Syndrome vs Toxic Epidermal Necrolysis

2018 ◽  
Vol 2 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Hannah Roberts Badon ◽  
Joy King ◽  
Robert T Brodell ◽  
Adam Byrd
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Clinical Features ◽  
Supportive Therapy ◽  
Accurate Diagnosis ◽  
Careful Attention ◽  
Staphylococcal Scalded Skin Syndrome ◽  
Clinical Appearance ◽  
Distinguishing Features

Staphylococcal scalded skin syndrome (SSSS) and toxic epidermal necrolysis (TEN) are dermatologic conditions that have a similar clinical appearance.  Careful attention to clinical features, such as the coloration at the base of the blister, and histopathology are utilized to make an accurate diagnosis.  While supportive therapy is required for both conditions, SSSS requires appropriate antibiotics to treat the underlying staphylococcus and TEN requires elimination of an offending drug (usually an antibiotic).  

scholarly journals Lupus Miliaris Disseminatus Faciei versus Granulomatous Rosacea: A Case Report

2021 ◽  
pp. 321-329
Author(s):  
Ji-In Seo ◽  
Min Kyung Shin
Keyword(s):  
Case Report ◽  
Case Studies ◽  
Clinical Features ◽  
Scar Formation ◽  
Accurate Diagnosis ◽  
Delayed Treatment ◽  
Inflammatory Dermatoses ◽  
Granulomatous Rosacea

Lupus miliaris disseminatus faciei (LMDF) and granulomatous rosacea are 2 distinct inflammatory dermatoses with overlapping clinical features: reddish-yellow papular eruptions localized on the central face. Consequently, LMDF can easily be misdiagnosed as granulomatous rosacea or vice versa. Because delayed treatment in LMDF may increase chances of permanent scar formation, accurate diagnosis is important. We therefore analyzed published literature and case studies to organize the essential features differentiating LMDF from granulomatous rosacea. In addition, we report each case of LMDF and granulomatous rosacea for direct comparison.

Clinical, Microbial, and Biochemical Aspects of the Exfoliative Toxins Causing Staphylococcal Scalded-Skin Syndrome

1999 ◽  
Vol 12 (2) ◽  
pp. 224-242 ◽  
Author(s):  
Shamez Ladhani ◽  
Christopher L. Joannou ◽  
Denise P. Lochrie ◽  
Robert W. Evans ◽  
Susan M. Poston
Keyword(s):  
Clinical Features ◽  
Treatment Options ◽  
Entire Body ◽  
Secondary Complications ◽  
Staphylococcal Scalded Skin Syndrome ◽  
Treatment And Prevention ◽  
Causative Agents ◽  
Underlying Diseases ◽  
Disease Understanding ◽  
Significant Mortality

SUMMARY The exfoliative (epidermolytic) toxins of Staphylococcus aureus are the causative agents of the staphylococcal scalded-skin syndrome (SSSS), a blistering skin disorder that predominantly affects children. Clinical features of SSSS vary along a spectrum, ranging from a few localized blisters to generalized exfoliation covering almost the entire body. The toxins act specifically at the zona granulosa of the epidermis to produce the characteristic exfoliation, although the mechanism by which this is achieved is still poorly understood. Despite the availability of antibiotics, SSSS carries a significant mortality rate, particularly among neonates with secondary complications of epidermal loss and among adults with underlying diseases. The aim of this article is to provide a comprehensive review of the literature spanning more than a century and to cover all aspects of the disease. The epidemiology, clinical features, potential complications, risk factors, susceptibility, diagnosis, differential diagnoses, investigations currently available, treatment options, and preventive measures are all discussed in detail. Recent crystallographic data on the toxins has provided us with a clearer and more defined approach to studying the disease. Understanding their mode of action has important implications in future treatment and prevention of SSSS and other diseases, and knowledge of their specific site of action may provide a useful tool for physiologists, dermatologists, and pharmacologists.

scholarly journals Staphylococcal scalded skin syndrome mimicking toxic epidermal necrolysis in a healthy adult

2013 ◽  
Vol 4 (3) ◽  
pp. 347-348
Author(s):  
Tomoko Oishi ◽  
Yuka Hanami ◽  
Yasunobu Kato ◽  
Mikio Otsuka ◽  
Toshiyuki Yamamoto
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Healthy Adult ◽  
Staphylococcal Scalded Skin Syndrome

scholarly journals Case Report: Bilateral mandibular buccal bifurcation cysts

F1000Research ◽  
2021 ◽  
Vol 9 ◽  
pp. 1502
Author(s):  
Ashwag Aloyouny ◽  
Hamad Albagieh ◽  
Soad Mansour ◽  
Fahmy Mobarak
Keyword(s):  
Case Report ◽  
Clinical Features ◽  
English Language ◽  
Accurate Diagnosis ◽  
Odontogenic Cyst ◽  
Optimal Management ◽  
Review Of The Literature

Buccal bifurcation cyst (BBC) is a rare inflammatory odontogenic cyst, which commonly affects children in the first decade of life. We report a case of a seven-year-old healthy boy with bilateral BBC, which involved unerupted incomplete permanent mandibular first molars. A review of the literature in English language revealed few similar cases. We reviewed 16 manuscripts of bilateral mandibular BBC, reporting a total of 20 cases since 1970. The clinical features of bilateral mandibular BBC summarized here could assist specialists with an accurate diagnosis and provide patients with optimal management.

scholarly journals Staphylococcal Scalded Skin Syndrome in Healthy Infant

2021 ◽  
Vol 5 (4) ◽  
pp. 1142-1150
Author(s):  
Anggia Perdana Harmen ◽  
Eny Yantri
Keyword(s):  
Staphylococcus Aureus ◽  
Toxic Epidermal Necrolysis ◽  
Otitis Media ◽  
Epidermolysis Bullosa ◽  
Erythema Multiforme ◽  
Skin Diseases ◽  
Chemical Burns ◽  
Staphylococcal Scalded Skin Syndrome ◽  
Focus Of Infection ◽  
Blistering Skin Disorders

Staphylococcal scalded skin syndrome (SSSS) describes a spectrum of superficial blistering skin disorders caused by the exfoliative toxins of Staphylococcus aureus that originates from a focus of infection that may be a purulent conjunctivitis, otitis media, or occult nasopharyngeal infection. It usually begins with fever, irritability, and a generalized, paint, orange-red, macular erythema with cutaneous tenderness, and the rash progress from scarlatiniform to a blistering eruption in 24 to 48 hours. A diagnosis must distinguish SSSS from other skin diseases, such as toxic epidermal necrolysis, epidermolysis bullosa, bullous erythema multiforme, Streptococcal impetigo or listeriosis and thermal or chemical burns, all of which can manifest with similar symptoms. The prognosis of SSSS in children who are appropriately treated is good, with a mortality of less than 5%. A case was a three moths old boy hospitalized in Pediatric ward M. Djamil hospital with chief complain redness and peeling of the skin since 2 days before hospitalized. Culture of the skin, eyes and nose was Staphylococcus aureus, and patients was given ampicillin and gentamycin for seven days.

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