The non-invasive spectrum analysis of radial pulse as a digital indicator for Type 2 Diabetic complication

Background: Hypothyroidism is an endocrine disorder resulting from deficiency of thyroid hormones, and Diabetes is a metabolic disorder that share the phenotype of hyperglycaemia. Both the endocrinopathies have been found to be associated with dyslipidaemia and atherosclerosis that result into various complications. Our aim was to assess the difference of dyslipidaemia in patients suffering from hypothyroidism with diabetes as compared to diabetes alone.Methods: Study was conducted in department of medicine in SGRDIMSR, Sri Amritsar. A total of 120 patients were enrolled for the present study, the one who presented to hospital from January 2018 to August 2019 diagnosed with diabetes mellitus type 2. The patients were divided into two groups. 60 patients having type 2 diabetes without hypothyroidism (control group). 60 patients having type 2 diabetes with hypothyroidism (study group). Fasting lipid profile were performed in both the groups and were analysed for the study.Results: Dyslipidaemia was seen more in study group as compared to control group with mean cholesterol of 488.3(±144.43) and mean triglyceride levels of 354.30(±128.57) in study group as compared to control group with mean cholesterol and triglyceride levels of 179.7(±81.47) and 177.08(±118.18) with p-value of 0.001 and 0.01 respectively which were significant. Also, obesity and diabetic complication were more in patients of dual endocrinopathies as compared to diabetes alone which were also significant statistically.Conclusions: From our study it is concluded that type 2 diabetes with hypothyroidism causes more dyslipidaemia as compare to type 2 diabetes alone. So proper screening of thyroid profile of type 2 diabetic patients and its correction helps in achieving better lipidemic control which further prevent complications.

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Medium-term prognostic value of angio-TC in type 2 diabetic patients without known cardiopathy

European Heart Journal Acute Cardiovascular Care ◽

10.1093/ehjacc/zuab020.005 ◽

2021 ◽

Vol 10 (Supplement_1) ◽

Author(s):

AM Garcia-Bellon ◽

AM Gonzalez Gonzalez ◽

C Lara-Garcia ◽

V Vivancos-Delgado

Keyword(s):

Coronary Angiography ◽

Ct Angiography ◽

Agatston Score ◽

Diabetic Patients ◽

Cardiac Events ◽

Type 2 Diabetic Patients ◽

Non Invasive ◽

Type 2 Diabetic

Abstract Funding Acknowledgements Type of funding sources: None. Introdution The use of coronary angiography by cardiac CT for the active search for coronary disease in asymptomatic diabetic patients is not generally indicated. On the other hand, in the case of high-risk patients with a high calcium score, there are results that do show a potential benefit of expanding the study with CT coronary angiography. Purpose The aim was to determine the medium-term prognostic value of computed tomography non-invasive coronary angiography (CT angiography) to predict major cardiac events in type 2 diabetic patients (p) without previous cardiac symptoms Methods Observational and prospective study in diabetic patients without symptoms suggestive of coronary heart disease (CHD), derived from performing a CT in the previous 5 years, for different reasons, not related to acute coronary syndrome. The presence of CHD was analyzed, as well as the incidence for cardiac events during follow-up. Results 402 diabetic patients, mean evolution time of the disease: 6.8 +/- 2.1 years, mean Hb1Ac 8.1 +/- 0.7%. 60% of patients were male. Regarding other cardiovascular risk factors: 66.3% were hypertensive. 58.8% dyslipidemic. 26.3% obese. 27.5% smokers. 32.5% ex-smokers. 36.3% had a family history of CHD. Most frequent indication for CT: CHD screening, with previous inconclusive tests (26.3%), followed by pre-surgery evaluation (25%). Agatston Score 278.3 ± 235.8, Agatston Score> 400 132 (32.8%), significant CHD 174 (43.2%), Vulnerable plaques 84 (20.9%) The average follow-up was 5 years (+/- 1.3); 90 p (22.3%) suffered cardiac events (63 cardiac deaths, 27 non-fatal myocardial infarction). Best correlation with events was observed with the presence of significant coronary disease (ostruction> 50%) compared to the Agatston score and the presence of vulnerable plaques (adjusted c-index of 0.59 versus univariate c-index of 0.42, respectively) The annual event rate for patients with normal coronary arteries was 1.8%, which translated into a 5-year event-free survival period. The highest annual event rate of 22.3% was detected in patients with obstructive 3-vessel CAD Conclusions Non-invasive CT angiography allows, after quantifying plaque severity in diabetic patients, to reclassify patients at high / very high risk Diabetic patients with normal coronary arteries on CT angiography had a 5-year survival period free of major cardiac events.

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A non-invasive method to estimate glucose levels in salivary secretions of diabetic patients

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20195598 ◽

2019 ◽

Vol 8 (1) ◽

pp. 60

Author(s):

Pramod Kumar Reddy Peddi ◽

Chandra Babu Singanamala ◽

Cheemalavagupalli Mounija

Keyword(s):

Blood Glucose ◽

Serum Glucose ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Glucose Levels ◽

Oral Rinse ◽

Non Invasive ◽

Blood Glucose Levels ◽

Type 2 Diabetic

Background: Aim of the study is to correlate between blood glucose levels and salivary glucose levels in type 2 diabetic patients, to study the relationship between salivary glucose levels and serum glucose levels in type 2 diabetic patients and to determine whether salivary glucose levels could be used as a non-invasive tool for the measurement of glycemic control in type 2 diabetics. This requirement of multiple pricking at regular intervals for monitoring serum glucose levels in the body is physically and psychologically traumatic to the patient. This necessitates a non-invasive procedure like salivary glucose estimation.Methods: The study population consisted of two groups: Group 1 consisted of 20 controlled diabetics and Group 2 consisted of 20 diabetics based on their random blood and salivary glucose levels. Two milliliters of peripheral blood were collected for the estimation of random blood glucose levels. Unstimulated saliva was collected by the oral rinse technique for the estimation of salivary glucose.Results: ANOVA single factor and Pearson correlation coefficient was carried out to know the statistical significance between the two groups. The salivary glucose levels were significantly higher in controlled and when compared with the diabetics. The salivary glucose levels showed a significant correlation with blood glucose levels, suggesting that salivary glucose levels can be used as a monitoring tool for predicting glycemic in diabetic patients.Conclusions: The present study found that estimation of salivary glucose levels can be used as a non-invasive, painless technique for the measurement of diabetic status of a patient in a dental set up.

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COVID -19: Case report of assertive treatment in diabetic patients

World Journal of Biology Pharmacy and Health Sciences ◽

10.30574/wjbphs.2021.7.1.0062 ◽

2021 ◽

Vol 7 (1) ◽

pp. 009-014

Author(s):

Glayson Guimarães Morais Ferreira ◽

Luciene dos Santos Ferreira Guimarães

Keyword(s):

Case Report ◽

Socioeconomic Inequality ◽

The Body ◽

Tetracycline Hydrochloride ◽

Diabetic Patients ◽

Non Invasive ◽

Invasive Method ◽

Impacting Factors ◽

Type 2 Diabetic

COVID 19 is currently one of the most impacting factors in world society, both because of the ineffectiveness of pharmacological measures and because of socioeconomic inequality. Diabetes is one of the comorbidities that makes the body more vulnerable to the development of severe COVID-19. Diabetes does not increase the patient's risk of becoming infected with the new coronavirus, but it does increase the chances of complications from the infection. This study uses a descriptive and observational methodology of the assertive evolution of the COVID-19 case report. It is a descriptive, exploratory, non-invasive method, with mediated intervention, in a 42-year-old male patient, type 2 diabetic, undergoing pharmacological monitoring and in treatment of lichenoid pityriasis with 500mg tetracycline hydrochloride, on alternate days. During treatment for pityriasis lichenoid, the patient contracted the coronavirus, changing the antibiotic for daily use, resulting in the remission of symptoms after 3 days of medication. This new scenario opens the possibility for clinical and scientific research through randomized studies of the antibiotic tetracycline hydrochloride 500 mg, to investigate its action on the viral replication of the new coronavirus.

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