Investigation of Fixed Oil of Gallus gallus domesticus for Various Pharmacological Activities

Medicinal oils, including fixed and essential oils, are one of the most ancient forms of medicines. Animals and plants are the major source of fixed oils which have been reported to treat various ailments, such as urinary, nervous, respiratory, cardiovascular, musculoskeletal disorders, bacterial, fungal and protozoal infections etc. Medicinal oils, especially of animal origin are; however, ignored and rarely investigated in contemporary modern medical research. This study was aimed to investigate the various pharmacological activities of fixed oil of Gallus gallus domesticus (Egg oil, Fo.Gg). Fo.Gg was investigated for its wound healing potential by using excisional wound model, anti-arthritic activity by following turpentine oil-induced acute arthritis model, antipyretic activity by yeast-induced pyrexia, anxiolytic activity by adopting hole board, light/dark exploration and elevated plus maze models, antidepressant activity by forced swim test and tail suspension model and antiamnesic activity by Y-maze model. Fo.Gg showed significant healing potential as evident from increase in percent wound contraction and decrease in period of epithelialization and also the significant decrease in paw and ankle joint diameter in anti-arthritic activity. It showed dose-dependent (i.e. 10, 30 and 50%) decrease in rectal temperature when compared to the control group, also showed significant anxiolytic, antidepressant and anti-amnesic activities. These pharmacological activities may be attributed to the antioxidant as well as radical scavenging potential of oil components especially polyphenols, oleic acid and linoleic acid. Thus, the results of the study conclude that egg oil possesses wound healing, anti-arthritic, antipyretic, anxiolytic, antidepressant and anti-amnesic potential. The study provides scientific ground for the folkloric use of the oil in traditional system of medicine; however, further studies are required to explore the possible mechanism(s) of action.

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A new paradigm for corneal wound healing research: The white leghorn chicken (Gallus gallus domesticus)

Current Eye Research ◽

10.1076/ceyr.28.4.241.27837 ◽

2004 ◽

Vol 28 (4) ◽

pp. 241-250 ◽

Cited By ~ 21

Author(s):

W. Craig Fowler ◽

Daniel H. Chang ◽

Bruce Clyde Roberts ◽

Elena L. Zarovnaya ◽

Alan D. Proia

Keyword(s):

Wound Healing ◽

Gallus Gallus ◽

Gallus Domesticus ◽

Gallus Gallus Domesticus ◽

White Leghorn ◽

New Paradigm ◽

Corneal Wound Healing ◽

White Leghorn Chicken ◽

Corneal Wound

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Identification of Functional Molecules and Pharmacological Activities Investigation of the Methanolic Extract of Egg Shell of Gallus Gallus Domesticus

Modern Applications of Bioequivalence & Bioavailability ◽

10.19080/mabb.2017.01.555561 ◽

2017 ◽

Vol 1 (3) ◽

Author(s):

Repon kumer S

Keyword(s):

Methanolic Extract ◽

Gallus Gallus ◽

Gallus Domesticus ◽

Gallus Gallus Domesticus ◽

Pharmacological Activities ◽

Egg Shell

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Teratological Effect of Indoxacarb on Chick Embryos (Gallus gallus domesticus)

Indian Journal of Animal Research ◽

10.18805/ijar.b-1179 ◽

2019 ◽

Author(s):

Safeer Abbas ◽

Razia Iqbal ◽

Sumbal Haleem ◽

Sadaf Niaz ◽

Riaz Ullah ◽

...

Keyword(s):

Gallus Gallus ◽

Gallus Domesticus ◽

Control Group ◽

Chick Embryos ◽

Gallus Gallus Domesticus ◽

Crown Rump Length ◽

Body Coloration ◽

Dose Concentration ◽

Eye Diameter ◽

Beak Length

The present study was designed to assess the teratological effects of Indoxacarb on chick embryos (Gallus gallus domesticus) by administering different doses of commercial Indoxacarb (0.5, 1.0 and 1.5ml/1000ml/egg, in three experimental groups B, C and D) injected into the yolk sac of eggs before incubation. Embryos were recovered at day 12 of incubation. The mortality rate gradually increased from lower to higher doses. A total of twelve morphometric parameters viz., wet body weight, crown rump length, anterior posterior head diameter, eye diameter, beak length, neck length, humerus length, radius and ulna length, metacarpus length, femur length, fibula length and metatarsus length were recorded and compared with control group. These quantitative parameters indicated significant plessthan0.05) decrease in all treated groups compared to control group. While the qualitative anomalies such as microcephaly, hydrocephaly, edematous swelling, hematoma formation, abnormal body coloration, anophthalmia, microphthalmia, deformed beak, agnathia, wry neck, micromelia, amelia, omphalocele and ectopia cardis were also recorded in treated groups as compared to untreated groups. Therefore, it is concluded that Indoxacarb has potentially harmful effects on the development of avian embryos even at very low dose concentration. Hence, due to toxicity of this pesticide it must be used with utmost caution.

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Teratogenic Effects of Chlorantraniliprole on chick embryos (Gallus gallus domesticus)

Indian Journal of Animal Research ◽

10.18805/ijar.b-569 ◽

2017 ◽

Author(s):

Safeer Abbas ◽

Razia Iqbal ◽

Muhammad Zeeshan Butt ◽

Sadaf Niaz ◽

Sumbal Haleem ◽

...

Keyword(s):

Gallus Gallus ◽

Gallus Domesticus ◽

Control Group ◽

Chick Embryos ◽

Gallus Gallus Domesticus ◽

Teratogenic Effects ◽

Crown Rump Length ◽

Body Coloration ◽

Dose Concentration ◽

Beak Length

The present study was designed to assess the teratogenic effects of Chlorantraniliprole on chick embryos (Gallus gallus domesticus). Different doses of commercial Chlorantraniliprole (0.1, 0.5, 1.0 and 1.5µl/1000µl/egg, in four experimental groups B, C, D, and E respectively) were injected into the yolk sac of eggs before incubation. Embryos were recovered at day 12 of incubation. The mortality rate gradually increased from lower to higher doses. A total of twelve morphometric parameters viz., wet body weight, crown rump length, anterior posterior head diameter, eye diameter, beak length, neck length, humor length, radius and ulna length, metacarpus length, femur length, fibula length and metatarsus length were recorded and compared with control group. These quantitative parameters indicated significant (p>0.05) decreases in all treated groups compared to control group. While the qualitative anomalies such as microcephaly, hydrocephaly, edematous swelling, hematoma formation, abnormal body coloration, microphthalmia, deformed beak, agnathia, micromelia, amelia, omphalocele and ectopia cardis were also observed in treated groups as compared to untreated groups. Therefore it is concluded that Chlorantraniliprole has potentially harmful effects on the development of avian embryos even at very low dose concentration. Hence, due to toxicity of this pesticide it can be used with utmost caution.

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A new cestode Raillietina (Skrjabinia) doggaddaensis n. sp. from Gallus gallus domesticus (L.) from India

The Korean Journal of Parasitology ◽

10.3347/kjp.1984.22.1.96 ◽

1984 ◽

Vol 22 (1) ◽

pp. 96 ◽

Cited By ~ 1

Author(s):

Sandeep K. Malhotra ◽

V. N. Capoor

Keyword(s):

Gallus Gallus ◽

Gallus Domesticus ◽

Gallus Gallus Domesticus

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Status of Diversity of Cestode Parasites of Domestic Fowl (Gallus Gallus Domesticus) from Nanded District, Maharashtra State

Indian Journal Of Applied Research ◽

10.15373/2249555x/oct2013/149 ◽

2011 ◽

Vol 3 (10) ◽

pp. 1-4

Author(s):

Dhanraj Balbhim Bhure ◽

◽

Sanjay Shamrao Nanware ◽

Namrata V Sunnap

Keyword(s):

Domestic Fowl ◽

Gallus Gallus ◽

Gallus Domesticus ◽

Gallus Gallus Domesticus

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Distribution of Melanin Pigmentation in 33 Organs of Thai Black-Bone Chickens (Gallus gallus domesticus)

Animals ◽

10.3390/ani10050777 ◽

2020 ◽

Vol 10 (5) ◽

pp. 777

Author(s):

Korakot Nganvongpanit ◽

Piyatida Kaewkumpai ◽

Varankpicha Kochagul ◽

Kidsadagon Pringproa ◽

Veerasak Punyapornwithaya ◽

...

Keyword(s):

Gallus Gallus ◽

Gallus Domesticus ◽

Melanin Pigment ◽

Gallus Gallus Domesticus ◽

Tissue Samples ◽

Melanin Pigmentation ◽

Chicken Breed ◽

Brachial Vein ◽

The Brain ◽

Pigment Accumulation

The black-bone chicken (Gallus gallus domesticus) is a breed of chicken that is commonly found in Thailand. This breed is known for having a number of black colored organs. Consumers have been notably attracted to the black-bone chicken breed for the characteristic darkness that is observed in many of its organs. However, the degree of darkness in all organs of the black-bone chicken is still in question. Importantly, there have not yet been any published reports on the distribution of melanin pigment in the organs of the black-bone chicken. This research study aims to examine the distribution of the melanin pigment in 33 organs of the Thai black-bone chicken. Ten black-bone chickens (five male, five female) were included in this study. Thirty-two organs including the brain, spinal cord, sciatic nerve, larynx, trachea, syrinx, lungs, heart, pericardium, aorta, brachial vein, kidney, cloaca, oviduct, testis, gastrocnemius muscle, femur, tongue, esophagus, crop, proventriculus, gizzard, duodenum, jejunum, ileum, cecum, pancreas, liver, gall bladder, omentum, abdominal fat, spleen, and skin were examined in this study. Histological sections taken from tissue samples of each of these organs were studied. The findings revealed that the presence of the melanin pigment was not significantly different (p > 0.005) between male and female specimens. Notably, the liver was the only organ in which the melanin pigment had not accumulated. Consequently, there was not a uniform pattern of melanin pigment accumulation throughout the organs of the chickens. The melanin pigment was present in all of the tissue layers of most organs, while the melanin pigment was found in only specific layers of some of the organs. In conclusion, the distribution of melanin pigmentation in the organs of each of the animals in this study was found to be different. However, in some tissue samples, such as those obtained from the liver, no accumulation of the melanin pigment was observed.

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