scholarly journals Identification of Functional Molecules and Pharmacological Activities Investigation of the Methanolic Extract of Egg Shell of Gallus Gallus Domesticus

Author(s):  
Repon kumer S
Author(s):  
Nadeem A ◽  
◽  
Ali H ◽  
Anwaar M ◽  
Jabeen Q ◽  
...  

Medicinal oils, including fixed and essential oils, are one of the most ancient forms of medicines. Animals and plants are the major source of fixed oils which have been reported to treat various ailments, such as urinary, nervous, respiratory, cardiovascular, musculoskeletal disorders, bacterial, fungal and protozoal infections etc. Medicinal oils, especially of animal origin are; however, ignored and rarely investigated in contemporary modern medical research. This study was aimed to investigate the various pharmacological activities of fixed oil of Gallus gallus domesticus (Egg oil, Fo.Gg). Fo.Gg was investigated for its wound healing potential by using excisional wound model, anti-arthritic activity by following turpentine oil-induced acute arthritis model, antipyretic activity by yeast-induced pyrexia, anxiolytic activity by adopting hole board, light/dark exploration and elevated plus maze models, antidepressant activity by forced swim test and tail suspension model and antiamnesic activity by Y-maze model. Fo.Gg showed significant healing potential as evident from increase in percent wound contraction and decrease in period of epithelialization and also the significant decrease in paw and ankle joint diameter in anti-arthritic activity. It showed dose-dependent (i.e. 10, 30 and 50%) decrease in rectal temperature when compared to the control group, also showed significant anxiolytic, antidepressant and anti-amnesic activities. These pharmacological activities may be attributed to the antioxidant as well as radical scavenging potential of oil components especially polyphenols, oleic acid and linoleic acid. Thus, the results of the study conclude that egg oil possesses wound healing, anti-arthritic, antipyretic, anxiolytic, antidepressant and anti-amnesic potential. The study provides scientific ground for the folkloric use of the oil in traditional system of medicine; however, further studies are required to explore the possible mechanism(s) of action.


Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 777
Author(s):  
Korakot Nganvongpanit ◽  
Piyatida Kaewkumpai ◽  
Varankpicha Kochagul ◽  
Kidsadagon Pringproa ◽  
Veerasak Punyapornwithaya ◽  
...  

The black-bone chicken (Gallus gallus domesticus) is a breed of chicken that is commonly found in Thailand. This breed is known for having a number of black colored organs. Consumers have been notably attracted to the black-bone chicken breed for the characteristic darkness that is observed in many of its organs. However, the degree of darkness in all organs of the black-bone chicken is still in question. Importantly, there have not yet been any published reports on the distribution of melanin pigment in the organs of the black-bone chicken. This research study aims to examine the distribution of the melanin pigment in 33 organs of the Thai black-bone chicken. Ten black-bone chickens (five male, five female) were included in this study. Thirty-two organs including the brain, spinal cord, sciatic nerve, larynx, trachea, syrinx, lungs, heart, pericardium, aorta, brachial vein, kidney, cloaca, oviduct, testis, gastrocnemius muscle, femur, tongue, esophagus, crop, proventriculus, gizzard, duodenum, jejunum, ileum, cecum, pancreas, liver, gall bladder, omentum, abdominal fat, spleen, and skin were examined in this study. Histological sections taken from tissue samples of each of these organs were studied. The findings revealed that the presence of the melanin pigment was not significantly different (p > 0.005) between male and female specimens. Notably, the liver was the only organ in which the melanin pigment had not accumulated. Consequently, there was not a uniform pattern of melanin pigment accumulation throughout the organs of the chickens. The melanin pigment was present in all of the tissue layers of most organs, while the melanin pigment was found in only specific layers of some of the organs. In conclusion, the distribution of melanin pigmentation in the organs of each of the animals in this study was found to be different. However, in some tissue samples, such as those obtained from the liver, no accumulation of the melanin pigment was observed.


Author(s):  
Webster Leonardo Guimarães da Costa ◽  
Isa Marianny Ferreira Nascimento Barbosa ◽  
Débora Pereira Gomes do Prado ◽  
Natália Domann ◽  
Hanstter Hallison Alves Rezende

2020 ◽  
Vol 23 (4) ◽  
pp. 769-780 ◽  
Author(s):  
Vitor Hugo Bessa Ferreira ◽  
Maxence Barbarat ◽  
Flore Lormant ◽  
Karine Germain ◽  
Mathilde Brachet ◽  
...  

2013 ◽  
Vol 195 (1-2) ◽  
pp. 203-204
Author(s):  
Caroline Gracielle Torres Ferreira ◽  
Cláudio Mafra ◽  
Ana Carla Diógenes Suassuna Bezerra ◽  
Otávio Valério de Carvalho ◽  
Abelardo Silva ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Aijuan Zheng ◽  
Anrong Zhang ◽  
Zhimin Chen ◽  
Shoaib Ahmed Pirzado ◽  
Wenhuan Chang ◽  
...  

Abstract Background Immunological stress decreases feed intake, suppresses growth and induces economic losses. However, the underlying molecular mechanism remains unclear. Label-free liquid chromatography and mass spectrometry (LC-MS) proteomics techniques were employed to investigate effects of immune stress on the hepatic proteome changes of Arbor Acres broilers (Gallus Gallus domesticus) challenged with Escherichia coli lipopolysaccharide (LPS). Results Proteomic analysis indicated that 111 proteins were differentially expressed in the liver of broiler chickens from the immune stress group. Of these, 28 proteins were down-regulated, and 83 proteins were up-regulated in the immune stress group. Enrichment analysis showed that immune stress upregulated the expression of hepatic proteins involved in defense function, amino acid catabolism, ion transport, wound healing, and hormone secretion. Furthermore, immune stress increased valine, leucine and isoleucine degradation pathways. Conclusion The data suggests that growth depression of broiler chickens induced by immune stress is triggered by hepatic proteome alterations, and provides a new insight into the mechanism by which immune challenge impairs poultry production.


Sign in / Sign up

Export Citation Format

Share Document