scholarly journals A Disposable Paper-Based Electrochemical Sensor Made of Pencil Graphite and Its Modification with Au for Detection of Glucose in Alkaline Solutions

Author(s):  
Mustafa Sen

Paper-based sensors have great potential to be used in a variety of fields ranging from environmental monitoring to clinical and point-of-care diagnostics. These sensors are disposable, cost effective, flexible and easy to use. The aim of this study was to fabricate a low cost, disposable, reliable and easy to use paper-based electrochemical sensor and its electrochemical modification with nanostructured Au for glucose detection in alkaline solutions.

2020 ◽  
Author(s):  
Mustafa Sen

Paper-based sensors have great potential to be used in a variety of fields ranging from environmental monitoring to clinical and point-of-care diagnostics. These sensors are disposable, cost effective, flexible and easy to use. The aim of this study was to fabricate a low cost, disposable, reliable and easy to use paper-based electrochemical sensor and its electrochemical modification with nanostructured Au for glucose detection in alkaline solutions.


2020 ◽  
Author(s):  
Mustafa Sen

Paper-based sensors have great potential to be used in a variety of fields ranging from environmental monitoring to clinical and point-of-care diagnostics. These sensors are disposable, cost effective, flexible and easy to use. The aim of this study was to fabricate a low cost, disposable, reliable and easy to use paper-based electrochemical sensor and its electrochemical modification with nanostructured Au for glucose detection in alkaline solutions.


Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1798
Author(s):  
Ravi Mani Tripathi ◽  
Sang J. Chung

The enzyme mimetic activity of nanomaterials has been applied in colorimetric assays and point-of-care diagnostics. Several nanomaterials have been exploited for their peroxidase mimetic activity toward 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide. However, an efficient nanomaterial for the rapid and strong oxidation of TMB remains a strategic challenge. Therefore, in this study, we developed copper-loaded tin oxide (SnO2-Cu) nanocomposites that rapidly oxidize TMB. These nanocomposites have strong absorption at 650 nm and can be used for highly sensitive colorimetric detection. An environmentally friendly (green), rapid, easy, and cost-effective method was developed for the synthesis of these nanocomposites, which were characterized using ultraviolet-visible, energy-dispersive X-ray, and Fourier-transform infrared spectroscopy, as well as scanning electron microscopy. This is the first green synthesis of SnO2-Cu nanocomposites. Their enzyme mimetic activity, which was first studied here, was found to be strongly dependent on the temperature and pH value of the solution. The synthesized nanocomposites have the advantages of low cost, high stability, and ease of preparation for enzyme mimetic applications. Hence, SnO2-Cu nanocomposites are a promising alternative to peroxidase enzymes in colorimetric point-of-care diagnostics.


2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Yehe Liu ◽  
Andrew M. Rollins ◽  
Richard M. Levenson ◽  
Farzad Fereidouni ◽  
Michael W. Jenkins

AbstractSmartphone microscopes can be useful tools for a broad range of imaging applications. This manuscript demonstrates the first practical implementation of Microscopy with Ultraviolet Surface Excitation (MUSE) in a compact smartphone microscope called Pocket MUSE, resulting in a remarkably effective design. Fabricated with parts from consumer electronics that are readily available at low cost, the small optical module attaches directly over the rear lens in a smartphone. It enables high-quality multichannel fluorescence microscopy with submicron resolution over a 10× equivalent field of view. In addition to the novel optical configuration, Pocket MUSE is compatible with a series of simple, portable, and user-friendly sample preparation strategies that can be directly implemented for various microscopy applications for point-of-care diagnostics, at-home health monitoring, plant biology, STEM education, environmental studies, etc.


2015 ◽  
Vol 9 (4) ◽  
Author(s):  
Liting Yi ◽  
Jingjing Li ◽  
Cangran Guo ◽  
Lei Li ◽  
Jing Liu

Pervasive detection of blood glucose is rather critical for the real-time disease diagnosis which would provide valuable guidance for treatment planning. Here, we established a health care platform for this purpose through incorporating the glucose detection with liquid metal printed sensor and the smart phone monitoring system together. The liquid metal ink composed of bismuth indium stannic (BIS) alloy was identified as an appropriate sensor material to be quickly written or printed on polyvinyl chloride (PVC) substrate at around 59 °C to form desired electrodes. It thus eliminated the complicated procedures as usually required in conventional sensor fabrication strategies. The alloy electrodes were characterized via cyclic voltammetry to demonstrate their practical functionality. Further, unlike using the commonly adopted glucometer, a smart phone was developed as the data acquisition and display center to help improve the portability and ubiquitous virtue of the detection system. Glucose solution in different concentrations was assayed via this platform. It was shown that there is a good linear relationship between the concentration and the integral value of the curve recorded by the mobile phone, which confirms the feasibility of the present method. This quantitative point-of-care system has pervasive feature and is expected to be very useful for future low-cost electrochemical detection.


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