Using Collision Cross Section Distributions to Assess the Distribution of Collision Cross Section Values
Keyword(s):
In this study we explore the use of collision cross section distributions to allow comparability of IM-MS data for proteins on different instruments. We present measurements on seven standard proteins across three IM-MS configurations, namely an Agilent 6560 IM QToF, a Waters Synapt G2 possessing a TWIMS cell and a modified Synapt G2 possessing an RF confining linear field drift cell. Mobility measurements were taken using both He and N<sub>2</sub> as the drift gases. To aid comparability across instruments and best assess the corresponding gas-phase conformational landscapes of the protein ‘standards’ we present the data in the form of averaged collision cross section distributions.
2017 ◽
2014 ◽
Vol 14
(4)
◽
pp. 543-546
◽
Keyword(s):
2011 ◽
Vol 308
(1)
◽
pp. 18-25
◽
2015 ◽
Vol 17
(39)
◽
pp. 25676-25688
◽
Keyword(s):
2017 ◽
Vol 421
◽
pp. 150-155
◽
2020 ◽
Vol 31
(10)
◽
pp. 2102-2110
Keyword(s):