scholarly journals A case of granulomatous tubulointerstitial nephritis in a patient with pulmonary sarcoidosis

2020 ◽  
Vol 92 (6) ◽  
pp. 81-83
Author(s):  
Leonid I. Dvoretsky ◽  
Sergei A. Krivushkin ◽  
Ekaterina S. Stolyarevich ◽  
Elizaveta A. Skrynnikova ◽  
Andrey P. Stepanchenko ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Biopsy ◽  
Replacement Therapy ◽  
Clinical Observation ◽  
Tubulointerstitial Nephritis ◽  
Pulse Therapy ◽  
Pulmonary Sarcoidosis ◽  
Interstitial Tissue ◽  
Extrapulmonary Manifestation

A clinical observation is presented of a patient with pulmonary sarcoidosis, who was diagnosed with kidney damage after three years with the development of chronic renal failure and the need for replacement therapy. A histological examination of the renal biopsy revealed a granulomatous process in the interstitial tissue, which was regarded as an extrapulmonary manifestation of sarcoidosis. Pulse therapy with glucocorticoids was prescribed and an attempt was made to reduce hemodialysis sessions.

Circulating Concentrations of Soluble Interleukin 6 Receptors gp80 and gp130 in Chronic Renal Failure and Effects ofRenal Replacement Therapy

1999 ◽  
Vol 19 (5) ◽  
pp. 571-575 ◽  
Author(s):  
Johan T.M. Frieling ◽  
Henk W. van Hamersvelt ◽  
John Wijdenes ◽  
Thijs Hendriks ◽  
Robert W. Sauerwein ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Replacement Therapy ◽  
Interleukin 6

scholarly journals Preeclampsia, HELLP Syndrome, and Postpartum Renal Failure with Thin Basement Membrane Nephropathy: Case Report and a Brief Review of Postpartum Renal Failure

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
K. C. Janga ◽  
Pavani Chitamanni ◽  
Shraddha Raghavan ◽  
Kamlesh Kumar ◽  
Sheldon Greenberg ◽  
...  
Keyword(s):  
Renal Failure ◽  
Basement Membrane ◽  
Renal Biopsy ◽  
Hellp Syndrome ◽  
Tubulointerstitial Nephritis ◽  
Laboratory Evaluation ◽  
High Dose ◽  
Acute Tubulointerstitial Nephritis ◽  
Thin Basement Membrane Nephropathy ◽  
First Case

A 36-year-old primigravida female from a birthing center was referred for elevated blood pressure to the hospital two days after normal spontaneous vaginal delivery with nausea, vomiting, and diarrhea. During this two-day period, she was experiencing persistent vaginal bleeding and lower abdominal pains for which she took six doses of 600 mg ibuprofen. Further laboratory evaluation reflected leukocytosis, anemia, thrombocytopenia, elevation of liver enzymes, and renal failure with hyperkalemia requiring emergent hemodialysis once in the Medical Intensive Care Unit (MICU). She was diagnosed with HELLP syndrome with underlying preeclampsia. A week later, due to hypertension controlled with medications and nonoliguric renal failure with no active urine sediments, a renal biopsy was indicated to direct management. The renal biopsy supported the diagnosis of diffuse severe acute tubulointerstitial nephritis with hypereosinophilia and thin basement membrane nephropathy (see figures). She was subsequently treated with high-dose steroids which resulted in the normalization of blood pressures and renal function returning to baseline. We report the first case of acute tubulointerstitial nephritis in an individual with thin basement membrane nephropathy secondary to postpartum complications.

Value of renal biopsy in chronic renal failure

1988 ◽  
Vol 20 (1) ◽  
pp. 77-83 ◽  
Author(s):  
M. Sobh ◽  
F. Moustafa ◽  
M. Ghoniem
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Biopsy

A tubulointerstitial nephritis antigen gene defect causes childhood-onset chronic renal failure

2010 ◽  
Vol 25 (7) ◽  
pp. 1349-1353 ◽  
Author(s):  
Yutaka Takemura ◽  
Machiko Koshimichi ◽  
Keisuke Sugimoto ◽  
Hidehiko Yanagida ◽  
Shinsuke Fujita ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Tubulointerstitial Nephritis ◽  
Gene Defect ◽  
Childhood Onset ◽  
Antigen Gene

The immune status of uraemic children/adolescents with chronic renal failure and renal replacement therapy

1989 ◽  
Vol 3 (3) ◽  
pp. 305-308 ◽  
Author(s):  
Raphael Drachman ◽  
Menahem Schlesinger ◽  
Hava Shapira ◽  
Alfred Drukker
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Immune Status ◽  
Uraemic Children

scholarly journals LOW OXYGENATION STATUS INCREASES NAUSEA-VOMITING INCIDENCE IN HEMODIALYSIS PATIENTS

2017 ◽  
Vol 2 (1) ◽  
pp. 21
Author(s):  
Cornelia DY Nekada ◽  
Mohamad Judha
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Oxygen Saturation ◽  
Respiratory Rate ◽  
Replacement Therapy ◽  
Nausea And Vomiting ◽  
Bivariate Analysis ◽  
P Value ◽  
Research Subjects ◽  
Oxygenation Status

Background and Objective: Data from Indonesia Basic Health Research (2013) states that the chronic renal failure in Indonesia is increasing, especially in Yogyakarta with the prevalence of chronic renal failure of 0,3%. If the patients of chronic renal failure are in End Stage Renal Disease (ESRD), the kidney needs replacement therapy to help its function. This therapy is called Continuous Renal Replacement Therapy (CRRT) or Hemodialysis (HD). Hemodialysis therapy may influence to the imbalance of oxyhemoglobin in the blood. Patients undergoing hemodialysis may experience intradialytic nausea and vomiting. The objective of this study is to identify whether there is a relationship between pre-dialysis oxygenation status through oxygen saturation (SpO2) and respiratory rate (RR) examination and the intradialytic nausea-vomiting occurrence. Method: This research is a comparative research with analytical cross sectional design. This research was conducted in hemodialysis room in Public Hospital of Panembahan Senopati Bantul. The subject of the research was taken using total sampling, by paying attention to research ethics. The total research subjects are 183 respondents. The researchers measured the oxygen saturation and patients’ respiratory rate and examined the intradialytic nausea and vomiting complaints. Result: The analysis result of Fisher’s exact in this research shows p value of 0,000 both in bivariate analysis of oxygen saturation to the nausea and vomiting occurrence and in bivariate analysis of the respiratory rate to the nausea and vomiting occurrence. The multivariate analysis employing regression logistic shows that the OR of oxygen saturation is 73,57, this means that the measurement of the abnormal oxygen saturation has the chance of seventy three times more to the nausea and vomiting occurrence, if compared to the patients with normal oxygen saturation. Conclusion and Suggestion: Intradialytic nausea and vomiting is one of the causes of the imbalance of oxyhemoglobin. The readiness of pre-dialysis oxygenation status needs to be noticed so that the nausea and vomiting complaints can be anticipated earlier.

scholarly journals Nutrition and Outcome on Renal Replacement Therapy of Patients with Chronic Renal Failure Treated by a Supplemented Very Low Protein Diet

2000 ◽  
Vol 11 (4) ◽  
pp. 708-716 ◽  
Author(s):  
MICHEL APARICIO ◽  
PHILIPPE CHAUVEAU ◽  
VALÉRIE DE PRÉCIGOUT ◽  
JEAN-LOUIS BOUCHET ◽  
CATHERINE LASSEUR ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Nutritional Status ◽  
Replacement Therapy ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Nutritional Parameters ◽  
Low Protein ◽  
Very Low Protein Diet

Abstract. Protein-restricted diets are prescribed in patients with chronic renal failure (CRF) to alleviate uremic symptoms and to slow the progression of CRF. The potential deleterious effects of protein restriction on nutritional status and clinical outcome of patients with CRF have raised concern. In this study, data were collected from 1985 to 1998 on 239 consecutive patients (age 50.2 ± 15.6 yr) with advanced CRF (GFR 13.1 ± 4.8 ml/min) to whom a supplemented very low protein diet (SVLPD) providing 0.3 g protein, 35 kcal, and 5 to 7 mg of inorganic phosphorus per kg per day was administered for a mean duration of 29.6 ± 25.1 mo. The diet was supplemented with essential amino acids and ketoanalogs, calcium carbonate, iron, and multivitamins. During SVLPD, protein intake decreased from 0.85 ± 0.23 to 0.43 ± 0.11 g/kg per d, and body mass index and serum albumin concentration remained unchanged overall. Fourteen patients died during SVLPD; death was unrelated to nutritional parameters. Hemodialysis was initiated after SVLPD in 165 patients at a mean GFR of 5.8 ± 1.5 ml/min. During an average of 54 mo on hemodialysis, mortality was low (2.4% after 1 yr) and correlated to age only, not to nutritional parameters observed at the end of SVLPD. Similar results were obtained in 66 transplanted patients (12 were not dialyzed before transplantation). SVLPD can be safely used in patients with CRF without adverse effects on the clinical and nutritional status of the patients. Due to the preservation of nutritional status and the correction of uremic symptoms, the initiation of dialysis was deferred in these patients. The outcome of patients on renal replacement therapy is not affected by prior treatment with SVLPD during the predialysis phase of CRF.

scholarly journals Can Renal Replacement Be Deferred by a Supplemented Very Low Protein Diet?

1999 ◽  
Vol 10 (1) ◽  
pp. 110-116
Author(s):  
MACKENZIE WALSER ◽  
SYLVIA HILL
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Diabetic Patients ◽  
Renal Survival ◽  
Low Protein ◽  
Very Low Protein Diet

Abstract. Patients with chronic renal failure are commonly started on renal replacement therapy (RRT) as soon as (or, in some centers, before) the usual criteria for severity are met,i.e., GFR <10 ml/min for nondiabetic patients and <15 ml/min for diabetic patients. To determine whether RRT can safely be deferred beyond this point, adults with all types of chronic renal failure who met these criteria on presentation (23 patients) or who reached these levels of severity during treatment (53 patients) were managed conservatively until RRT was judged necessary by their chosen dialysis or transplantation team, without input into this decision from the present authors. Patients were prescribed a very low protein diet (0.3 g/kg) plus supplemental essential amino acids and/or ketoacids and followed closely. The intervals between the time at which GFR became less than 10 ml/min (15 ml/min in diabetic patients) and the date at which renal replacement therapy was started were used as estimates of renal survival on nutritional therapy. Kaplan—Meier analysis showed median renal survival of 353 d. Acidosis and hypercholesterolemia were both predictive of shorter renal survival. Signs of malnutrition did not develop. Final GFR averaged 5.6 ± 1.9 ml/min. Two patients died; thus, annual mortality was only 2.5%. Hospitalizations totaled 19 in 93 patient-years of treatment, or 0.2 per year. Thus, these well motivated patients with GFR <10 ml/min (<15 ml/min in diabetic patients) were safely managed by diet and close follow-up for a median of nearly 1 yr without dialysis. It is concluded that further study of this approach is indicated.

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