scholarly journals Level of abstinence mediates heart-rate response to cue-elicited craving in smokers

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Jared T. Kelly ◽  
Sean P. Barrett ◽  
Robert O. Pihl ◽  
Alain Dagher
Keyword(s):  
Heart Rate ◽  
Negative Reinforcement ◽  
Cue Reactivity ◽  
Incentive Motivation ◽  
Critical Determinant ◽  
Autonomic Responses ◽  
Reinforcing Value ◽  
Neutral Material ◽  
Cigarette Craving ◽  
Physiologic Responses

The subjective and autonomic components of nicotine craving were examined in abstinent and non-abstinent smokers using a cue reactivity paradigm. A cigarette abstinent condition was used to examine how smoking deprivation mediates the activity of positive and negative reinforcement mechanisms. Levels of craving and physiologic responses were monitored during the presentation of videotaped neutral and smoking stimuli. Relative to the neutral material, smoking stimuli increased several indices of subjective craving in both abstinent and non-abstinent smokers. Autonomic responses to the smoking stimuli however, appeared to be mediated by the level of abstinence. Non-deprived smokers showed an increase in heart rate during the first minute of the smoking stimuli presentation relative to the first minute of the control video, while abstinent smokers showed no change. The autonomic responses of cigarette craving may be dependent on the perceived reinforcing value of cigarettes, which can be modulated by cigarette abstinence. These findings are consistent with the hypothesis that increased heart rate may be a marker for incentive motivation, but also strongly support a multi-dimensional model of nicotine craving. Furthermore, they stress the importance of recognising the condition of the smoker as a critical determinant in craving responses.

Age dependency of cardiovascular autonomic responses to head-up tilt in healthy subjects

2004 ◽  
Vol 96 (6) ◽  
pp. 2333-2340 ◽  
Author(s):  
Tomi Laitinen ◽  
Leo Niskanen ◽  
Ghislaine Geelen ◽  
Esko Länsimies ◽  
Juha Hartikainen
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
High Frequency ◽  
Healthy Subjects ◽  
Baroreflex Sensitivity ◽  
Low Frequency ◽  
Upright Position ◽  
Vascular Responses ◽  
Autonomic Responses ◽  
Head Up Tilt

In elderly subjects, heart rate responses to postural change are attenuated, whereas their vascular responses are augmented. Altered strategy in maintaining blood pressure homeostasis during upright position may result from various cardiovascular changes, including age-related cardiovascular autonomic dysfunction. This exploratory study was conducted to evaluate impact of age on cardiovascular autonomic responses to head-up tilt (HUT) in healthy subjects covering a wide age range. The study population consisted of 63 healthy, normal-weight, nonsmoking subjects aged 23–77 yr. Five-minute electrocardiogram and finger blood pressure recordings were performed in the supine position and in the upright position 5 min after 70° HUT. Stroke volume was assessed from noninvasive blood pressure signals by the arterial pulse contour method. Heart rate variability (HRV) and systolic blood pressure variability (SBPV) were analyzed by using spectral analysis, and baroreflex sensitivity (BRS) was assessed by using sequence and cross-spectral methods. Cardiovascular autonomic activation during HUT consisted of decreases in HRV and BRS and an increase in SBPV. These changes became attenuated with aging. Age correlated significantly with amplitude of HUT-stimulated response of the high-frequency component ( r = -0.61, P < 0.001) and the ratio of low-frequency to high-frequency power of HRV ( r = -0.31, P < 0.05) and indexes of BRS (local BRS: r = -0.62, P < 0.001; cross-spectral baroreflex sensitivity in the low-frequency range: r = -0.38, P < 0.01). Blood pressure in the upright position was maintained well irrespective of age. However, the HUT-induced increase in heart rate was more pronounced in the younger subjects, whereas the increase in peripheral resistance was predominantly observed in the older subjects. Thus it is likely that whereas the dynamic capacity of cardiac autonomic regulation decreases, vascular responses related to vasoactive mechanisms and vascular sympathetic regulation become augmented with increasing age.

scholarly journals Heart Rate Variability (HRV) and Pulse Rate Variability (PRV) for the Assessment of Autonomic Responses

2020 ◽  
Vol 11 ◽  
Author(s):  
Elisa Mejía-Mejía ◽  
Karthik Budidha ◽  
Tomas Ysehak Abay ◽  
James M. May ◽  
Panayiotis A. Kyriacou
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Pulse Rate ◽  
Pulse Rate Variability ◽  
Autonomic Responses

Assessment of Autonomic Responses to Different Driving and Road Conditions

2000 ◽  
Vol 44 (37) ◽  
pp. 679-679
Author(s):  
Byung-Chan Min ◽  
Soon-Cheol Chung ◽  
Sang-Gyun Kim ◽  
Byung-Woon Min ◽  
Chul-Jung Kim ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Skin Temperature ◽  
Galvanic Skin Response ◽  
Physiological Responses ◽  
Mean Value ◽  
Autonomic Responses ◽  
Skin Response ◽  
Curved Road

The purpose of this study was to compare changes in autonomic responses due to different driving and road conditions. We measured physiological responses of the 10 health subjects such as Heart Rate Variability (HRV), Galvanic Skin Response (GSR) and skin temperature in rest and stimulation conditions. The ratio of LF/HF significantly increased and averaged R-R interval decreased on the abrupt stopping and starting and abruptly curved road conditions, compared to other conditions. Mean value of GSR increased and mean value of skin temperature decreased in the abrupt stopping and starting and abruptly curved road conditions, compared to other conditions.

scholarly journals Greater effort boosts the affective taste properties of food

2010 ◽  
Vol 278 (1711) ◽  
pp. 1450-1456 ◽  
Author(s):  
Alexander W. Johnson ◽  
Michela Gallagher
Keyword(s):  
Foraging Behaviour ◽  
Incentive Motivation ◽  
Separate Experiment ◽  
Schedules Of Reinforcement ◽  
Initial Experiment ◽  
Training Environment ◽  
Causal Factors ◽  
Reinforcing Value ◽  
Directed Action ◽  
The Relationship

Actions can create preferences, increasing the value ascribed to commodities acquired at greater cost. This behavioural finding has been observed in a variety of species; however, the causal factors underlying the phenomenon are relatively unknown. We sought to develop a behavioural platform to examine the relationship between effort and reinforcer value in mice trained under demanding or lenient schedules of reinforcement to obtain food. In the initial experiment, expenditure of effort enhanced the value of the associated food via relatively lasting changes in its hedonic attributes, promoting an acquired preference for these reinforcers when tested outside of the training environment. Moreover, otherwise neutral cues associated with those reinforcers during training similarly acquired greater reinforcing value, as assessed under conditioned reinforcement. In a separate experiment, expenditure of effort was also capable of enhancing the value of less-preferred low-caloric reinforcers. Analysis of licking microstructure revealed the basis for this increased valuation was, in part, due to increased palatability of the associated reinforcer. This change in the hedonic taste properties of the food can not only serve as a basis for preference, but also guide decision-making and foraging behaviour by coordinating a potentially adaptive repertoire of incentive motivation, goal-directed action and consumption.

A genetic polymorphism of the α2-adrenergic receptor increases autonomic responses to stress

2004 ◽  
Vol 96 (6) ◽  
pp. 2231-2239 ◽  
Author(s):  
J. Clayton Finley ◽  
Michael O'Leary ◽  
Derin Wester ◽  
Steven MacKenzie ◽  
Neil Shepard ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Individual Differences ◽  
Lower Body Negative Pressure ◽  
Lower Body ◽  
Gene Encoding ◽  
Autonomic Responses ◽  
Sweat Sodium

We hypothesized that individual differences in autonomic responses to psychological, physiological, or environmental stresses are inherited, and exaggerated autonomic responsiveness may represent an intermediate phenotype that can contribute to the development of essential hypertension in humans over time. α2-Adrenergic receptors (α2-ARs), encoded by a gene on chromosome 10, are found in the central nervous system and also mediate release of norepinephrine from the presynaptic nerve terminals of the peripheral sympathetic nervous system and the exocytosis of epinephrine from the adrenal medulla. We postulated that, because this receptor mediates central and peripheral autonomic responsiveness to stress, genetic mutations in the gene encoding this receptor may explain contrasting activity of the autonomic nervous system among individuals. The restriction enzyme Dra I identifies a polymorphic site in the 3′-transcribed, but not translated, portion of the gene encoding the chromosome 10 α2-AR. Southern blotting of genomic DNA with a cDNA probe after restriction enzyme digestion results in fragments that are either 6.7 kb or 6.3 kb in size. Transfection studies of these two genotypes resulted in contrasting expression of a reporter gene, and it is suggested from these findings that this is a functional polymorphism. In a study of 194 healthy subjects, we measured autonomic responses to provocative motion, a fall in blood pressure induced by decreasing venous return and cardiac output, or exercise. Specifically, we measured reactions to 1) Coriolis stress, a strong stimulus that induces motion sickness in man; 2) heart rate responses to the fall in blood pressure induced by the application of graded lower body negative pressure; and 3) exercise-induced sweat secretion. In all of these paradigms of stress, subjective and objective evidence of increased autonomic responsiveness was found in those individuals harboring the 6.3-kb allele. Specifically, volunteers with the 6.3-kb allele had greater signs and symptoms of motion sickness mediated by the autonomic nervous system after off-axis rotation at increasing velocity (number of head movements a subject could complete during rotation before emesis ± SE: 295 ± 18 vs. 365 ± 11; P = 0.001). They also had greater increases in heart rate in responses to the lower body negative pressure-induced fall in blood pressure (increase in heart rate ± SE: 3.0 ± 0.4 vs. 1.8 ± 0.3; P = 0.012), and the 6.3-kb group had higher sweat sodium concentrations during exercise (mean sweat sodium concentration in meq/l over 30 min of exercise ± SE: 43.2 ± 7.1 vs. 27.6 ± 3.4; P < 0.05). This single-nucleotide polymorphism may contribute to contrasting individual differences in autonomic responsiveness among healthy individuals.

Sensitivity of the Yo-Yo Intermittent Recovery Test and Cardiac Autonomic Responses to Training in Futsal Players

2015 ◽  
Vol 10 (5) ◽  
pp. 553-558 ◽  
Author(s):  
Victor H. de Freitas ◽  
Lucas A. Pereira ◽  
Eberton A. de Souza ◽  
Anthony S. Leicht ◽  
Maurizio Bertollo ◽  
...  
Keyword(s):  
Heart Rate ◽  
Efficient Method ◽  
Recovery Test ◽  
Autonomic Responses ◽  
Training Adaptations ◽  
Maximal Performance ◽  
Highly Sensitive ◽  
Monitoring Training ◽  
Induced Changes

Purpose:This study examined the sensitivity of maximal (Yo-Yo Intermittent Recovery [IR] 1 and 2) and submaximal (5’-5’) tests to identify training adaptations in futsal players along with the suitability of heart-rate (HR) and HR-variability (HRV) measures to identify these adaptations.Methods:Eleven male professional futsal players were assessed before (pretraining) and after (posttraining) a 5-wk period. Assessments included 5’-5’ and Yo-Yo IR1 and IR2 performances and HR and HRV at rest and during the IR and 5’-5’ tests. Magnitude-based-inference analyses examined the differences between pre- and posttraining, while relationships between changes in variables were determined via correlation.Results:Posttraining, Yo-Yo IR1 performance likely increased while Yo-Yo IR2 performance almost certainly increased. Submaximal HR during the Yo-Yo IR1 and Yo-Yo IR2 almost certainly and likely, respectively, decreased with training. HR during the 5’-5’ was very likely decreased, while HRV at rest and during the 5’-5’ was likely increased after training. Changes in both Yo-Yo IR performances were negatively correlated with changes in HR during the Yo-Yo IR1 test and positively correlated with the change in HRV during the 5’-5’.Conclusions:The current study has identified the Yo-Yo IR2 as more responsive for monitoring training-induced changes of futsal players than the Yo-Yo IR1. Changes in submaximal HR during the Yo-Yo IR and HRV during the 5’-5’ were highly sensitive to changes in maximal performance and are recommended for monitoring training. The 5’-5’ was recommended as a time-efficient method to assess training adaptations for futsal players.

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