scholarly journals Factors affecting health-related quality of life and its association with the Xmn1-Gγ polymorphism among adolescents with transfusion-dependent beta thalassemia and HbE/β-thalassemia in East Coast Malaysia

2020 ◽  
Vol 5 (2) ◽  
pp. 30-36
Author(s):  
Wardah Yusof ◽  
Maryam Mohd Zulkifli ◽  
Nurul Fatihah Azman ◽  
Siti Azrin Ab Hamid ◽  
Azizah Othman ◽  
...  
Author(s):  
Kisook Kim ◽  
Hyohyeon Yoon

The study aimed to identify and compare the factors affecting health-related quality of life (HRQoL) depending on the occupational status of cancer survivors. This study was a secondary data analysis from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2014 to 2018. Hierarchical multivariate linear regression was used to investigate the factors affecting the HRQoL of each group. Non-working cancer survivors had significantly lower HRQoL than working cancer survivors (p < 0.001). A hierarchical multiple regression model showed that demographic, health-related, and psychological characteristics explained 62.0% of non-working cancer survivors’ HRQoL (F = 4.29, p < 0.001). Among the input variables, health-related characteristics were the most influential factors (ΔR2 = 0.274, F = 9.84, p < 0.001). For working cancer survivors, health-related characteristics were the only variable that was statistically associated with HRQoL (F = 5.556, p < 0.001). It is important to enhance physical activities and manage the chronic disease to improve the HRQoL of working cancer survivors. Further, managing health-related characteristics, including depressive symptoms and suicidal ideation, is necessary for non-working cancer survivors. Regarding working survivors, psychological factors such as depressive symptoms and suicidal tendencies did not affect HRQoL. Therefore, an early and effective return to work program should be developed for the improvement of their HRQoL.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1889-1894
Author(s):  
Setareh Dastyar Haghighi ◽  
Vandhita Nair ◽  
Vas Sonali Maria ◽  
Gopika K S ◽  
Divya Mol E C ◽  
...  

Alcohol induced cirrhosis prevalence has increased worldwide of late and has added markedly to the global burden of diseases. However, research involving quality of life as treatment outcome for alcoholic liver disease is limited. The primary objective of the study was to evaluate the health related quality of life and factors affecting it in alcoholic liver disease patients. Secondary objective was to analyze mental health status and prescription pattern in alcoholic liver disease patients. Patients, eligible to participate, were briefed regarding the purpose of the study and informed consent was obtained. Self-designed case report form and validated questionnaires were used to record information on physical, mental and emotional functioning of the patient. The study included 51 patients. It was found that majority had low quality of life scores with role limitation due to physical health (5.39 ± 16.9) domain being the most affected. It was also found that the symptom fatigue caused the most hindrance to patient’s daily activities (1.31± 1.20). Most of the patients reported having mild depression (50.98%). Prescription analysis showed that diuretics (74.50%) and drugs for hepatic encephalopathy were the most commonly used drugs. The present study found that alcoholic liver disease considerably impaired health related quality of life and identified the contributing factors as presence of complication, age, severity of disease and symptoms like fatigue and abdominal pain. Hence, evaluating factors affecting quality of life and prescription patterns help identify targets for novel treatment strategies.


2016 ◽  
Vol 20 (6) ◽  
pp. 738-746 ◽  
Author(s):  
J. Y. Yoo ◽  
Y. S. Kim ◽  
S. S. Kim ◽  
H. K. Lee ◽  
C. G. Park ◽  
...  

2015 ◽  
Vol 3 (4) ◽  
pp. 360-366 ◽  
Author(s):  
Emre Acaroglu ◽  
Umit O. Guler ◽  
Z. Deniz Olgun ◽  
Yalcin Yavuz ◽  
Ferran Pellise ◽  
...  

2020 ◽  
Author(s):  
Kil-Yong Jeong ◽  
Hyun Jung Lee

Abstract Background: The purpose of this study was to analyze the risk factors affecting the prevalence of osteoarthritis and the health-related quality of life (HRQoL) of stroke patients from various angles, including demographic factors, socioeconomic factors, comorbidities, and lifestyle factors.Methods: A total of 13,959 patients ≥40 years of age (stroke group n = 416, non-stroke group n = 13,535) were identified from the 2016–2018 Korean National Health and Nutrition Examination Survey for analysis. The European quality of life-5 dimensions questionnaire was used to compare the differences in stroke patient’s HRQoL according to the presence or absence of osteoarthritis. Multiple regression analysis was performed to determine the factors affecting the HRQoL of the stroke group.Results: The prevalence of osteoarthritis was 21.72% in the stroke group and 12.49% in the non-stroke group. The prevalence of osteoarthritis in female patients who had strokes was 35.95% and was significantly higher than that of male patients who had strokes (10.23%). The European quality of life-5 dimensions index indicating HRQoL was significantly lower in stroke group with osteoarthritis. Factors that significantly influenced the HRQoL in the stroke group were the presence of osteoarthritis, aerobic exercise, drinking status, types of health insurance, and educational levels.Conclusions: This study confirmed that the HRQoL was significantly lower in stroke group with osteoarthritis. Findings were taken to suggest that the active management of osteoarthritis in stroke patients are important.


2021 ◽  
Author(s):  
Abdullah Ali Gafer ◽  
Nabil Ahmed Al-Rabeei ◽  
Mohammed Sadeg Al-Awar

Abstract Background: Identifying and understanding the variables that influence health-related quality of life (HRQoL) in patients with thalassemia is critical to creating more appropriate clinical, counseling, and social support programs to develop treatment results for these individuals. The purpose of this investigation is to investigate the variables that are related with HRQOL in thalassemic patients in Yemen. Methods: From July to September 2020, a descriptive, cross-sectional investigation was carried out among Thalassemia patients who attended the Yemen Society for Thalassemia. a total of 344 individuals with Thalassemia between the ages of 5 and 18 years old. Data were gathered by utilizing the Pediatric Quality of Life 4.0 as face to face interview with children and their parents. The scale consisted of four domains (Physical, emotional, social, and school functioning) and other related demographic and clinical characteristics of the patients. coefficient tests as appropriate. Two-tailed, p-value <0.05 was regarded statistically considerable.Results:The findings of the investigation displayed that the Thalassemia patients were males with a percentage of (54.9%)Thetotal HRQoL mean score was found to be (50.6±16.5) with the highest mean scores in the social (69.3±20.2) and emotional (55.9±20.7) functioning domains. There was correlation between age, education, residency, and total HRQoL scores, which was statistically significant (P-value<0.05). There was correlation between iron overload complications, pre-transfusion Hb level, received iron chelation, and total HRQoL scores (P-value<0.05).Conclusions:Appropriate programs focused at providing psychological support to thalassemia patients are needed to improve their HRQoL. The results also supported the significance of keeping a pretransfusion hemoglobin level of at least 9-10.5 g/dL prior to the transfusion procedure.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 971
Author(s):  
Atta Ur Rehman ◽  
Rubeena Zakar ◽  
Muhammad Zakria Zakar ◽  
Ume Hani ◽  
Florian Fischer

Background: Pakistan served as a host for more than 1.4 million Afghan refugees for more than 40 years. Access to health care is the most important issue faced by refugees, because they might be at a higher risk for certain diseases. This risk can be attributed to a lack of awareness of health care facilities, health beliefs, inadequate hygiene, cultural differences, and malnutrition. Health of individuals is closely associated with their quality of life. Quality of life over the whole lifespan is pivotal to overall life satisfaction. It includes physical wellbeing, mental health, education, occupation, income, personal safety, as well as (religious) freedom. Until now, the health status of Afghan refugees has never been comprehensively investigated in Pakistan. Therefore, an assessment in this regard is needed to explore their health-related quality of life, for securing their human right to health. Methods: A cross-sectional study has been designed to describe and explain the health-related quality of life of Afghan refugees in Pakistan. Multistage cluster sampling was applied for selection of study participants. The number of respondents from two regions in Pakistan was drawn through a proportionate sampling technique. A quantitative research method using pre-validated questionnaires was used for data collection. The questionnaire included items to assess well-being, mental health, health literacy, and factors affecting health and health care. Descriptive analysis was used, whereas inferential statistical tests (binary logistic regression model) was also performed. The study received ethically permission by the Advanced Studies and Research Board of the University of the Punjab, Lahore, Pakistan. Discussion: The assessment of Afghan refugee’s quality of life in Pakistan should lead to recommendations disseminated to public and health care officials. This evidence is needed for policymaking related to adequate measures for improving health conditions of Afghan refugees in Pakistan.


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