scholarly journals Paraganglioma of the nasal cavity. case report

2020 ◽  
Keyword(s):  
Nasal Cavity ◽  
Abdominal Cavity ◽  
Fibrous Tissue ◽  
Malignant Neoplasm ◽  
The Body ◽  
Surgical Removal ◽  
Morphological Examination ◽  
Diagnostic Measures ◽  
Eosinophilic Cytoplasm ◽  
The Right

Paraganglioma is one of the tumors that is rarely found in the practice of an otorhinolaryngologist. Approximately 90% of tumors from nonchromaffin paraganglia occur in the adrenal glands. Nevertheless, 5 – 10 % of paragangliomas have different localization: 85 % - in the abdominal cavity, 12 % - in the chest, 3 % - on the head and neck. Paraganglioma grows slowly, but there is a risk of its degeneration into a malignant neoplasm. Diagnosis of paraganglioma includes CT, MRI; Ultrasound scintigraphy, arteriography, biopsy, histological examination. The main treatment for this education is surgical. As this tumor occurs rather rarely, we present a clinical observation of a paraganglioma of the nasal cavity. Purposes. The purpose of this article is to describe a rare clinical case of paraganglioma of the nasal cavity to determine diagnostic measures and treatment tactics to help a practical doctor. Materials and methods. On 01/18/2019 patient M., 52 years old, with complaints of recurrent nosebleeds, difficulty breathing in the right half of the nose was received at the ENT Center «V. T. Lisovets Dynasty». Bleeding from the nasal cavity has been disturbing the patient twice a week for 6 months, for no apparent reason. An increase in the frequency of bleeding up to 4–5 times a week has been noticed for the last month. On a series of MRI tomograms dated 12.24.2019, in the front sections of the nasal concha, on the right, a volumetric pathological formation with dimensions of about 10 × 12 mm, with tuberous contours, an inhomogeneous MR structure was determined. Bone structures were not affected. The neoplasm narrowed the lumen of the nasal cavity on the right. Conclusion: MR-picture of the pathological volumetric formation (of blastomatous nature) of the nasal cavity on the right. Results. On 01/21/2019 the patient underwent surgical removal of the neoplasm within healthy tissues using a radioknife. An anterior nasal tamponade with a hemostatic preparation was performed. The postoperative period was without complications. A morphological examination of surgical material N 330/2019 yielded the following results: a microscopic examination determined a tumor with the same histological picture in the form of alveolar and solid areas, a branched network of blood vessels of capillary type, fibrous tissue of various thicknesses. Tumor parenchyma was represented by epithelioid morphology cells with pronounced eosinophilic cytoplasm, a large nucleus with granular chromatin. Cells with a weakly expressed eosinophilic cytoplasm, with small monomorphic nuclei were also found. Conclusions. The patient was diagnosed with a rare tumor of neuroectodermal nature, which in most cases has a benign nature, slow growth and develops from nonchromaffin ganglia, which are scattered throughout the body. As the formation grows, the arterial and venous network of vessels develops. The clinical picture of a neoplasm of the nasal cavity is often masked by the symptoms of chronic polypousrhinosinusitis, vasomotor and chronic hypertrophic rhinitis. Based on the foregoing, this clinical cases valuable for the practitioner in terms of the features of localization, diagnosis and these lection of the correct therapy for this category of patients.

scholarly journals Granular cell tumor that originated in a posterior ethmoid sinus

2017 ◽  
Vol 3 (3) ◽  
pp. 721
Author(s):  
Myung Woo Kim ◽  
Sun Hee Chang ◽  
Ick Soo Choi
Keyword(s):  
Nasal Cavity ◽  
Nasal Polyp ◽  
Granular Cell Tumor ◽  
Neuron Specific Enolase ◽  
Granular Cell ◽  
Ethmoid Sinus ◽  
Cell Tumor ◽  
The Body ◽  
Eosinophilic Cytoplasm ◽  
The Right

<p class="abstract"><span lang="EN-US">A granular cell tumor (GCT) is a rare neoplasm. It grows slowly, presumably originates from a Schwann cell, and is typically benign. Histopathologically, GCTs are composed of loosely infiltrating sheets of large, pale, polyhedral cells with abundant granular eosinophilic cytoplasm and a pale, centrally situated nucleus. Immunohistochemically, GCTs express the S-100 protein and neuron-specific enolase. A GCT can occur anywhere in the body. Half of all GCTs occur in the head and neck regions, especially on the tongue, but they are rarely found in the nasal cavity. A GCT usually arises as a solitary tumor and can be confirmed only by a histologic examination. The appropriate treatment is excision of the lesion. </span>Here, we present a rare case of a GCT originating in the right posterior ethmoid sinus in the nasal cavity. A GCT originating in a posterior ethmoid sinus has not been reported thus far. In our case, a simple nasal polyp was found in the left ethmoid sinus of the patient. Thus, we initially misjudged the GCT in the right nasal cavity as a simple nasal polyp.</p>

Myiasis in Bufo regularis caused by a Tabanid Larva

Parasitology ◽  
1924 ◽  
Vol 16 (1) ◽  
pp. 111-112
Author(s):  
Edward Hindle
Keyword(s):  
Fibrous Tissue ◽  
Dorsal Surface ◽  
Body Cavity ◽  
The Body ◽  
Careful Examination ◽  
Large Female ◽  
Considerable Time ◽  
Ventral Region ◽  
Cylindrical Structure ◽  
The Right

In December, 1922, whilst dissecting a large female example of Bufo regularis, one of my students noticed a cylindrical structure extending along the ventral region of the body-cavity. A careful examination showed that this structure consisted of an elongated sac-like diverticulum of the right lung, containing an almost full-grown specimen of a dipterous larva, which could be seen through the membraneous wall of the diverticulum. The base of the latter, in addition to its point of origin from the lung, was also connected to the dorsal surface of the liver by strands of fibrous tissue, suggesting that the growth had been in existence some considerable time in order to cause such adhesions. Posteriorly, the diverticulum hung freely in the body cavity and extended to the extreme hinder end. Its dimensions were 5·5 cm. in length, by 0·5 cm. in diameter, but tapering towards each extremity.

scholarly journals Inverted Papilloma of Nasal Septum

2012 ◽  
Vol 27 (2) ◽  
pp. 39-40
Author(s):  
Min Han Kong ◽  
Bee See Goh
Keyword(s):  
Nasal Cavity ◽  
Endoscopic Resection ◽  
Nasal Septum ◽  
Surgical Techniques ◽  
Inverted Papilloma ◽  
Surgical Removal ◽  
Lateral Nasal Wall ◽  
Endoscopic View ◽  
The Right

Dear Editor,   Papillomas are primary benign epithelial neoplasms producing finger–like projections that typically cover fibrous stalks.1 The term Inverted Papilloma (IP) describes the endophytic projection of epithelium into the stroma. Also known as Schneiderian papillomas, IPs predominantly affect males in the 6th decade.2 They usually arise from the lateral nasal wall and seldom involve the frontal or sphenoid sinuses.2 The frequency of IP on the nasal septum is even less.3 We report a case of IP of the nasal septum and the role of endoscopic resection of the IP without any sign of recurrence.   CASE REPORT A 52-year-old man who was a chronic smoker and worked as a cook presented with a 1-year history of progressively worsening unilateral nasal blockage and hyposmia. Rigid nasoendoscopy revealed a reddish grape-like mass filling the right nasal cavity. The mass extended posteriorly to the posterior nasal space and crossed to the left side and had a broad-based attachment to the posterosuperior part of the nasal septum. Computed tomography (CT) scan showed a heterogeneously-enhanced soft tissue density mass in the right nasal cavity and a soft tissue density in the right ethmoid and sphenoid sinus most likely representing retained secretions. The patient underwent endoscopic excision of the mass using Integrated Power Console (IPC®) system coupled to Straightshot® M4 microdebrider (Medtronic, Minneapolis MN, USA) under general anaesthesia. After induction, each nostril was packed with five rayon neuro-patties (Ray-cot®, American Surgical Company, Lynn MA, USA) soaked with 2mls cocaine 10%, 2mls adrenaline 1:1000 and 6mls of water, carefully placed along the septum, floor and turbinate region. This method reduces the bleeding significantly and prevents blood from impairing the endoscopic view. During the operation, a septal perforation was found at the origin of the mass. No further removal of nasal septum was performed. Histopathological examination (HPE) confirmed the diagnosis of Inverted Papilloma. He has been under our follow-up for the past 5 years and remains well and symptom-free with no evidence of recurrence detected on endoscopic examination.   DISCUSSION Inverted Papilloma (IP) poses many clinical, pathological and even management challenges. There are various surgical techniques advocated for treating IP. Radical transfacial approaches like lateral rhinotomy, minimally invasive endoscopic techniques and even midfacial degloving procedures are among some of the surgical techniques  advocated.4 Most authors agree that complete surgical removal is the hallmark in treating IP.1, 2, 4, 5 Traditionally, en bloc excision of the lateral nasal wall via lateral rhinotomy approach is the standard surgical option for IP arising from the lateral nasal wall. This approach provides good access to the tumor. Despite achieving complete surgical removal, IP tends to recur.1 Recurrence rates of IP when treated surgically are as high as 71%.2 Persistent disease is unacceptable especially with the possibility of malignant transformation.1, 2 It is reported that malignancy in IP is particularly high at 10 to 15%.1                With regard IP of the  nasal septum, Lawson et al. in 1995 reported 5 of 112 IP patients (4%) with isolated septal lesions that were treated by septectomy.6 Our patient underwent transnasal endoscopic resection of the tumor without further need of posterior septectomy. The tumor was removed using a microdebrider. Using the microdebrider for septal surgery usually involves a lateral (PNS and nasal cavity) to medial (septum) process, and posterior inferior to anterior superior shaving technique, also minimizes blood from impairing the endoscopic view. Any visible tumor at the margins was also removed. Unlike conventional polypectomy, complete removal of the tumor and sterilization of the margins is the hallmark in treating IP. Removal of IP without sterilization of the margins should be avoided. Sterilization of the margin is not necessarily by microdebrider only;  other authors have reported debulking tumor completely and sterilizing the margins and underlying bone using a diamond burr.5               Transnasal endoscopic surgery avoided aggressive surgery and facial scarring in this patient. We observed no evidence of recurrence on follow up to date using this method. Although this tumor has the ability to destroy bone, tends to recur, and is associated with malignancy, we demonstrated that transnasal endoscopic resection of IP limited to nasal septum may be safely performed without the need for further septectomy. However, we do not advocate this technique in cases of large tumor or when malignancy is suspected. Endoscopic surgery would not adequately visualize the whole tumor and risk recurrence of tumor.2 Larger series and better study design are required to support our observation and establish an acceptable and safe technique indicated for IP on the nasal septum.         

scholarly journals OPERATION STRESS AND ITS INFLUENCE ON THE SYSTEM CHANGES IN CASE OF ABDOMINAL COMBINED TRAUMA (EXPERIMENTAL RESEARCH)

2018 ◽  
Vol 17 (2) ◽  
pp. 31-36
Author(s):  
V. O. Krylyuk ◽  
V. K. Hrodetsʹkyy ◽  
S. O. Sokolʹnyk ◽  
O. V. Fedosyeyeva ◽  
H. Yu. Tsymbalyuk
Keyword(s):  
Superoxide Dismutase ◽  
Abdominal Cavity ◽  
The Body ◽  
Control Group ◽  
Systemic Response ◽  
Antioxidant Protection ◽  
Operational Stress ◽  
Experimental Animals ◽  
Ischemic Reperfusion ◽  
The Right

The aim of the study was to study the possibility of using a hemostatic biological haemostatic to stop bleeding from the parenchymal organs of the abdominal cavity using the surgical method of Damage control. The experiment was performed on laboratory rats that were divided into three groups: a control group, a group where, after injury, the liver wound was sutured with standard sutures and a group where the wound was plastered with a biological hemostatic agent. In order to determine the operational stress, we studied the enzymatic link of antioxidant protection - the level of catalase and superoxide dismutase. To study the indices in all experimental animals, the following tissues were taken: the lower lobe of the right lung, the proportion of the liver where the wounds were applied, the gastrocnemius muscle below the harness and the right kidney. The control points of the study were 1, 3 and 7 days after injury. During working with experimental animals, they adhered to all ethical norms established by international rules. The effect of operational stress on the enzymatic component of antioxidant protection in the tissues of the kidneys, liver, lungs and muscles was studied in the study of the combined trauma of the abdominal cavity complicated by massive bleeding and ischemic-reperfusion syndrome of the extremity. The changes in the indices of superoxide dismutase and catalase were studied. The following result was obtained: tamponing the liver wound with chitosan was a quick and effective means of temporary bleeding stop. At the same time, the duration of the operation was reduced from 19.8 to 12.5 minutes (by 36.8%) (p <0.05). Also, the level of catalase and superoxide dismutase was significantly lower in the group where the chitosan of the liver injury was used in comparison with the study group where standard stitches were applied. The deviations, which are determined in lung, liver, kidney and muscle tissues in RG-1 are evidence of the depth of their lesion and dysfunction, is a favorable factor for the further development of the triggering mechanisms of the systemic response of the body to inflammation and multiple organ failure. In contrast to the RG-2 rapid development of the systemic response was avoided. We can assume that ischemic-reperfusion syndrome is a stimulating factor in the development of systemic changes, although this statement requires further proof. It is also important to further prospective study of this topic in terms of the following questions: what effect has chitosan on liver tissue with prolonged exposure (more than 2 days) and what effect does additional injection of infusion solutions have as an agent for the treatment of hypovolemic shock.

scholarly journals Lateral nasal wall haemangioma in a young female: a rare case

2020 ◽  
Vol 6 (11) ◽  
pp. 2139
Author(s):  
Ashfaque Ansari ◽  
Sanjana U. Nair
Keyword(s):  
Nasal Cavity ◽  
Head And Neck ◽  
Neck Region ◽  
Young Female ◽  
The Body ◽  
Lateral Nasal Wall ◽  
Vascular Structures ◽  
Benign Tumours ◽  
The Right ◽  
Mixed Types

<p class="abstract">Hemangiomas are benign tumours originating from vascular structures in the body. Histologically they are divided into capillary, cavernous and mixed types. Although it is very commonly seen in head and neck region, it is very rarely seen in the nasal cavity, nasopharynx and paranasal sinuses and it accounts for only 10% of all head and neck haemangiomas. In this patient the haemangioma was seen arising from the lateral nasal wall, of the right nasal cavity. So far in the literature very few such cases have been reported till date.  </p>

scholarly journals Nasal Cryptococcosis Caused by Cryptococcus gattii in Sheep in Bahia, Northeastern Brazil

2020 ◽  
Vol 48 ◽  
Author(s):  
Alan Greison Costa Macêdo ◽  
Tiago Da Cunha Peixoto ◽  
Vitor Santiago De Carvalho ◽  
Luciano Nakazato ◽  
Iris Daniela Santos De Meneses ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
The State ◽  
Northeastern Brazil ◽  
Surgical Removal ◽  
Nasal Discharge ◽  
Soap Bubble ◽  
Cryptococcus Spp ◽  
The Right ◽  
First Time ◽  
Irregular Mass

Background: Cryptococcosis is a potentially fatal systemic mycosis that can affect several animal species. The disease is caused by the yeast species Cryptococcus neoformans and C. gattii and is usually associated with immunosuppressive diseases or debilitating factors. In Brazil, cryptococcosis in ruminants has been described in several states, but there have been only two instances of infection in sheep. Until the present, cryptococcosis caused by C. gattii has only been reported in goats. The objective of this study was to describe, for the first time, a case of nasal cryptococcosis caused by C. gattiiin a sheep in the state of Bahia.Case: The disease affected a 4-year-old Santa Inês sheep, created in extensive system in the municipality of Ribeira do Pombal, Bahia, Brazil. The animal presented weight loss, with an asymmetric volume increase in the right nasal cavity, accompanied by dyspnea and bloody nasal discharge. Samples of the tumor mass were collected for cytological analysis of yeast structures compatible with Cryptococcus spp. After cytological diagnosis, the sheep was sent to the Livestock Development Center of the Federal University of Bahia. On physical examination, there was a large and firm irregular mass, strongly adhering to the right nasal cavity and causing facial asymmetry. Surgical removal was attempted, but a marked infiltrative character of the lesion was observed, with extensive tissue destruction. Owing to the unfavorable prognosis, euthanasia was carried out followed by necropsy, in which a large irregular mass was observed that almost completely obliterated the right nasal cavity. Resorption of the right nasal bone and the dorsal and middle nasal turbinates was also observed. Fragments of the nasal lesion were collected, fixed in 10% formalin, routinely processed for histopathology, and stained with hematoxylin and eosin (HE) and Mayer's mucicarmine. Samples of this lesion were sent for molecular characterization of the etiologic agent by polymerase chain reaction (PCR). The histopathological evaluation showed hundreds of generally colorless rounded yeasts cells composed of a clear halo, surrounding a slightly basophilic structure, giving the tissue a vacuolated aspect, known as a “soap bubble lesion” There was also intense inflammatory infiltration and extensive areas of necrosis and hemorrhage, which allowed the morphological diagnosis of diffuse granulomatous rhinitis marked with intralesional yeasts compatible with Cryptococcus spp. Additionally, PCR was positive for C. gattii.Discussion: A case of nasal cryptococcosis caused by C. gattii in sheep in the state of Bahia is described for the first time, diagnosed using clinical-epidemiological, cytological, anatomopathological, and molecular data. Airborne infection occurs by inhaling encapsulated spores present in organic matter, such as decomposing vegetables and bird and bat excreta as observed on the farm where the outbreak occurred. It is important to highlight that sheep and goats affected by cryptococcosis can contaminate the environment, and it is prudent to consider animals with the disease as a risk to public health and eliminate them from the herd, given the costs of the few therapeutic options available on the market. It should be noted that in cases of tumor lesions, which are common in cryptococcosis, cytological examination should be recommended, mainly for screening and distinguishing neoplastic and inflammatory lesions. However, anatomopathological and molecular evaluations are essential for the differential diagnosis of other mycotic rhinitis, in particular,  conidiobolomycosis and nasal pythiosis.

Adrenal Cortical Adenoma in the Spinal Canal: A Case Report and Review of the Literature

2019 ◽  
Vol 81 (01) ◽  
pp. 071-074
Author(s):  
Jakob Nemir ◽  
Martina Štenger ◽  
Antonia Jakovčević ◽  
Ivan Domazet ◽  
Niko Njirić ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Canal ◽  
Traumatic Injury ◽  
Spinal Tumor ◽  
Surgical Removal ◽  
Adrenal Cortical Adenoma ◽  
Mri Features ◽  
Eosinophilic Cytoplasm ◽  
Abundant Eosinophilic Cytoplasm ◽  
The Right

AbstractEctopic adrenal cortical neoplasms of the spinal cord are extremely rare. To date only 10 such cases have been described. We present a case of a 46-year-old woman with lower back pain radiating to the right gluteal and posterior femoral regions, without a history of traumatic injury. Magnetic resonance imaging (MRI) of the thoracic and lumbar spine showed an intradural, extramedullary, well-circumscribed, contrast-enhancing lesion located in the T12–L1 region, hypo- to isointense on T2-weighted imaging, and isointense on T1. Complete surgical removal of the lesion, measuring 3 × 2.5 × 1 cm, was performed. The histopathologic findings revealed the lesion was an ectopic adrenal cortical adenoma, with sheets and nests of round and polygonal cells, mostly round regular nuclei, abundant eosinophilic cytoplasm, 1 mitosis per 10 high-power fields, and without necrosis. These tumors have nonspecific MRI features and therefore can be easily confused with other common spinal tumor types such as ependymoma, schwannoma, meningioma, and metastasis. Although rare, ectopic adrenal spinal cord adenomas should be taken into account in the differential diagnosis of spinal canal intradural neoplasms.

Teratocarcinosarcoma of the nasal cavity and ethmoid

1998 ◽  
Vol 112 (7) ◽  
pp. 682-686 ◽  
Author(s):  
Hari Shankar Sharma ◽  
Jafri Malin Abdullah ◽  
Nor Hayati Othman ◽  
Mahayidin Muhamad
Keyword(s):  
Nasal Cavity ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Malignant Neoplasm ◽  
Intracranial Extension ◽  
Local Destruction ◽  
Sinonasal Teratocarcinosarcoma ◽  
Rare Malignancy ◽  
The Right ◽  
Epithelial Element

AbstractSinonasal teratocarcinosarcoma is very unusual malignant neoplasm histologically consisting of an epithelial element and one or more mesenchymal components. This is a report of teratocarcinosarcoma, in a 74-year-old male, involving the right nasal cavity and ethmoids with intracranial extension. The tumour was totally resected via the craniofacial approach and the patient was given post-operative chemotherapy. Extensive tumour necrosis, rapid growth and local destruction are the prominent features of this tumour. The clinical presentation, pathological features and clinical course of this rare malignancy are discussed with a review of the literature.

Conservative surgical management of a supernumerary tooth in the nasal cavity

2020 ◽  
Vol 13 (7) ◽  
pp. e235718
Author(s):  
Vineet Kumar ◽  
Akhilesh Bhaskar ◽  
Roohi Kapoor ◽  
Pratima Malik
Keyword(s):  
Foreign Body ◽  
Nasal Cavity ◽  
General Anaesthesia ◽  
Surgical Management ◽  
Nasal Congestion ◽  
Surgical Removal ◽  
Supernumerary Tooth ◽  
Ectopic Tooth ◽  
Foreign Body Obstruction ◽  
The Right

A 9-year-old girl presented with a foreign body obstruction inside her nose. The condition led to pain and nasal congestion. CT showed the presence of a radiopaque mass similar to a tooth in the right nasal cavity. Diagnosis of a supernumerary intranasal tooth was made and extraction was performed under general anaesthesia. An ectopic tooth in the nasal cavity is rare and surgical removal is recommended to eliminate the symptoms.

scholarly journals Metachronous Colon Metastasis to the Thyroid: A Case Report and Literature Review

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Dvir Froylich ◽  
Eitan Shiloni ◽  
David Hazzan
Keyword(s):  
Thyroid Gland ◽  
Colon Carcinoma ◽  
Malignant Neoplasm ◽  
Colon Resection ◽  
The Body ◽  
Thyroid Lobe ◽  
Carcinoma Metastasis ◽  
Thyroid Metastases ◽  
The Right ◽  
Metastatic Colon Carcinoma

The thyroid gland is a known site for metastatic tumors from various primary sites. Thyroid metastases are not an exceptional finding at autopsy, and they are encountered in 2% to 9% of the patients with malignant neoplasm. The most frequent tumors to metastasize are breast, lung, melanoma, and kidney carcinomas. Despite the fact that it is one of the largest vascular organs in the body, clinical and surgical cases have given an incidence of 3% of secondary malignances of this organ. Metastatic colon carcinoma to the thyroid gland has been reported, and it is not as rare as one might think. We present a very unique case of colon carcinoma metastasis to the right thyroid lobe and lung five years after colon resection, with reoccurrence two years later in the contralateral thyroid lobe. The literature regarding colon cancer metastasizing to the thyroid gland was reviewed with an attempt to disclose features of this presentation regarding patient’s prognosis.

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