scholarly journals Mortality forecast from gastroduodenal ulcer disease for different gender and age population groups in Ukraine.

2016 ◽  
Vol 21 (1) ◽  
pp. 134-139
Author(s):  
I. D. Duzhiy ◽  
S. O. Muntyan ◽  
V. Yu. Dubnitskiy ◽  
S. V. Kharchenko ◽  
V. A. Smianov
Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5084
Author(s):  
Javier P. Gisbert

H. pylori infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. Fluoroquinolones such as levofloxacin, or more recently moxifloxacin or sitafloxacin, are efficacious alternatives to standard antibiotics for H. pylori eradication. The aim of the present review is to summarize the role of quinolone-based eradication therapies, mainly focusing on the optimization strategies aimed to increase their efficacy. Several meta-analyses have shown that, after failure of a first-line eradication treatment, a levofloxacin-containing rescue regimen is at least equally effective, and better tolerated, than the generally recommended bismuth quadruple regimen. Compliance with the levofloxacin regimens is excellent, and the safety profile is favourable. Higher cure rates have been reported with longer treatments (>10–14 days), and 500 mg levofloxacin daily is the recommended dose. Adding bismuth to the standard triple regimen (PPI-amoxicillin-levofloxacin) has been associated with encouraging results. Unfortunately, resistance to quinolones is easily acquired and is increasing in most countries, being associated with a decrease in the eradication rate of H. pylori. In summary, a quinolone (mainly levofloxacin)-containing regimen is an encouraging second-line (or even third-line) strategy, and a safe and simple alternative to bismuth quadruple therapy in patients whose previous H. pylori eradication therapy has failed.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1668 ◽  
Author(s):  
Katsumi Iizuka ◽  
Daisuke Yabe

Conventional recommendations for dietary intervention have been generally based on population groups divided by gender and age [...]


2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Javier P. Gisbert

Helicobacter pyloriinfection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After 30 years of experience inH. pyloritreatment, however, the ideal regimen to treat this infection has still to be found. Nowadays, apart from having to know well first-line eradication regimens, we must also be prepared to face treatment failures. In designing a treatment strategy, we should not only focus on the results of primary therapy alone but also on the final—overall—eradication rate. The choice of a “rescue” treatment depends on which treatment is used initially. If a first-line clarithromycin-based regimen was used, a second-line metronidazole-based treatment (quadruple therapy) may be used afterwards, and then a levofloxacin-based combination would be a third-line “rescue” option. Alternatively, it has recently been suggested that levofloxacin-based “rescue” therapy constitutes an encouraging 2nd-line strategy, representing an alternative to quadruple therapy in patients with previous PPI-clarithromycin-amoxicillin failure, with the advantage of efficacy, simplicity and safety. In this case, quadruple regimen may be reserved as a 3rd-line “rescue” option. Even after two consecutive failures, several studies have demonstrated thatH. pylorieradication can finally be achieved in almost all patients if several “rescue” therapies are consecutively given.


2007 ◽  
Vol 54 (1) ◽  
pp. 165-167
Author(s):  
S.N. Krstic ◽  
T. Alempijevic ◽  
M.N. Krstic ◽  
Z.D. Lausevic ◽  
A. Sijacki ◽  
...  

Introduction: Acute bleeding from the upper gastrointestinal tract remains the commonest emergency in gastroenterology, and is most often caused by gastroduodenal ulcer disease. Despite introduction of novel endoscopic techniques and pharmacological treatment, 6-15% patients have to be operated. The aim of our investigation is analyze data of patients treated for gastrointestinal ulcer bleeding in our institution, their treatment options and outcome. Patients and methods: We included 2237 patients admitted in the Department for Emergency medicine of Clinical center of Serbia during the period from January 1999 until December 2003. because of gastroduodenal ulcer bleeding. We analyzed age, gender treatment option, hospital stay and mortality. Results: The mean age of our patients was 61.58 years, 1346 male and 891 female. The majority of patients were conservatively treated (84.5%). Operated patients mostly undergo Billroth II resection (57.8%). The mean hospital stay was 7.3 days. Average mortality was 14.4% Conclusions: Despite adequate endoscopic management of bleeding gastroduodenal ulcer, surgeons will continue to treat this patients for emergency surgery.


Author(s):  
Wolfgang Fischbach ◽  
Peter Malfertheiner ◽  
Jörg C. Hoffmann ◽  
Wolfgang Bolten ◽  
Manfred Kist ◽  
...  

2020 ◽  
Author(s):  
Faisal Aziz ◽  
Yasmeen Taj ◽  
Shahana Urooj Kazmi

AbstractHelicobacter pylori is a causative agent of gastritis, gastroduodenal ulcers and gastric adenocarcinoma. Gastric patient’s serums were screened for H. pylori infection by thin layer immunoassay. A polystyrene plate coated with H. pylori sonicate whole cell antigen (10 μg/ml). Two fold-diluted patient’s serum was allowed to react at 37 °C, incubated at 60 °C for 1 min over water bath and recorded water condensation pattern for H. pylori antibody. Gastric patient’s blood samples (62% male and 6% female) were tested positive for H. pylori, while agewise 15–25 years males (36%) and 65–75 years females (50%) showed highest number of H. pylori infection. Thin layer immunoassay showed sensitivity (72–67%), specificity (100%), accuracy (94–69%) and κ value (0.493–0.357) in comparison with wELISA, sELISA and kELISA. We conclude thin layer immunoassay was reliable, low cost, quick, simple and clinically useful method for H. pylori diagnosis in patients of Pakistan.


Curationis ◽  
2004 ◽  
Vol 27 (2) ◽  
Author(s):  
A. Le Roux

Many young people today are lonely and hopeless, and feel that life has no meaning. The existing literature indicates that this phenomenon is taking on near-epidemic proportions in industrialised Western countries. A considerable amount of cross-cultural investigations have already been conducted overseas between different population groups, in order to determine what the causes of this phenomenon are and whether culture plays an important role in the development of loneliness. As far as this type of research is concerned South Africa is currently far behind the rest of the world. Serious efforts shall have to be made to determine whether loneliness is taking on the same proportions locally and if certain population groups are more vulnerable than others, because it could have far-reaching consequences on their physical as well as psychological health. South Africa has a rich population variety which could enable researchers to investigate emotional constructs like loneliness that could contribute to the unravelling of this multifaceted phenomenon. The purpose of this investigation was therefore to determine whether students from different cultural backgrounds at the University of the Free State differ from each other, as far as their experience of loneliness is concerned. Questionnaires were distributed among students and 270 respondents, of which 122 were white and 148 black, took part in this study. A factorial analysis of variance was applied on the data, with loneliness as dependent variable, and cultural background, gender and age as independent variables. The results firstly show that cultural background is a very important variable as far as loneliness is concerned. Black students are significantly more lonely than white students while no gender and age differences between the groups were found.


2000 ◽  
Vol 24 (3) ◽  
pp. 321-327 ◽  
Author(s):  
Teruaki Aoki ◽  
Sumio Takayama ◽  
Hiroshi Nimura ◽  
Jun Tsutsumi

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