ASSESSMENT OFTHE SEVERITY OF ACUTE OBSTRUCTIVE BRONCHITIS AND BRONCHIOLITIS IN EARLY CHILDREN DEPENDING ON THE LEVEL OF OXIPROLIN IN THE BLOOD

2021 ◽  
Vol Special issue (1) ◽  
pp. 5-10
Author(s):  
Makhzuna Mukhsinova ◽  
◽  
Rano Yunusova ◽  
Khilola Ilkhamova

The article presents data on the state of collagen metabolism in terms of oxyproline in the blood, its clinical significance for assessing the severity and outcome of the disease, the criterion for the effectiveness of therapy in children of early age withacute obstructive bronchitis and bronchiolitis. The author recommends to determine the level of free and protein-bound oxyproline in blood plasma, an increase in which reflects the degree of destruction in the bronchopulmonary apparatus. The inclusion of immunomodulin into the basic treatment contributes to an increase in the effectiveness of therapy, a reduction of treatment duration.Keywords: oxyproline, bronchitis and bronchiolitis, immunomodulin, treatment, children

2021 ◽  
Vol 25 (3 (99)) ◽  
pp. 97-101
Author(s):  
V. Ratsa ◽  
O. Fedіv

Changes in oxidative-antioxidant homeostasis is one of the pathogenetic links in the onset and progression of many nosologies, including chronic pancreatitis (CP) and hypothyroidism (HТ), however, data on the development of oxidative stress (OS) with a combination of CP and HP are insufficient, therefore, determining the role of these systems with a comorbid course of these pathologies is an urgent issue of our time.The aim of the work is to study the state of the oxidative and antioxidant system in patients with CP and CP combined with HT.Material and methods. 96 people were examined, including 26 patients with chronic pancreatitis (group 1), 24 patients with hypothyroidism (group 2), 26 patients with chronic pancreatitis on the background of hypothyroidism (group 3), 20 almost healthy individuals (group 4). Evaluation of the oxidative-antioxidant system and lipid peroxidation was assessed by determining the content of malonic aldehyde in blood plasma (MA pl.) And erythrocytes (MA er.), The level of reduced glutathione, glutathione peroxidase (GP) and glutathione-S-trans-ion (GT). Enzyme activity was calculated per 1 g of hemoglobin (HB).Research results. The analysis of the obtained results revealed clear patterns of changes in the state of the oxidative-antioxidant system and lipid peroxidation in patients with chronic pancreatitis on the background of hypothyroidism. Namely, violation of lipid peroxidation in patients with comorbid pathology, accompanied by an increase in the content of MA er. by 44.87% and the content of MA in blood plasma by 46.42%; oxidative-antioxidant system: decrease in HF in the blood by 51,61%, combined of a compensatory increase in BP - by 48.03% and HT - by 34.76%.Conclusion. Under the conditions of comorbidity of CP and HT, there is a violation of the oxidative-antioxidant system and the state of lipid peroxidation, which is characterized by a significant increase in MA in erythrocytes and MA in plasma against a decrease in glutathione and which complicates the course of the underlying disease, its diagnosis and treatment.


1953 ◽  
Vol 46 (2) ◽  
pp. 443-453 ◽  
Author(s):  
Isaac Feldman ◽  
Jean R. Havill ◽  
W.F. Neuman

2019 ◽  
Vol 166 (3) ◽  
pp. 373-376 ◽  
Author(s):  
N. E. Kushlinskii ◽  
E. S. Gershtein ◽  
A. A. Ivannikov ◽  
M. M. Davydov ◽  
V. L. Chang ◽  
...  

Biorheology ◽  
1979 ◽  
Vol 16 (6) ◽  
pp. 397-402 ◽  
Author(s):  
A. Ganssen ◽  
H. Schmid-Schönbein ◽  
H. Malotta ◽  
R. Schneider

Author(s):  
A. V. Lizarev ◽  
V. A. Pankov

When exposed to noise and vibration in experimental animals there was a decrease in the content of threeiodinethyronine, thyroxin and adrenocorticotropic hormone in blood plasma after 15 and 30 days of experience. An increase in loads led to an increase in the level of threeiodinethyronine and thyroxin under vibration exposure and was normalized with noise. The content of adrenocorticotropic hormone leveled in both cases.


1950 ◽  
Vol 162 (1) ◽  
pp. 182-188 ◽  
Author(s):  
J. H. Meyer ◽  
R. R. Grunert ◽  
Marie T. Zepplin ◽  
R. H. Grummer ◽  
G. Bohstedt ◽  
...  

Talanta ◽  
2021 ◽  
Vol 225 ◽  
pp. 121900
Author(s):  
Lukasz Oldak ◽  
Anna Sankiewicz ◽  
Beata Żelazowska-Rutkowska ◽  
Bogdan Cylwik ◽  
Zenon Lukaszewski ◽  
...  

1953 ◽  
Vol 204 (1) ◽  
pp. 147-152 ◽  
Author(s):  
Shirley F. McCann ◽  
M. Laskowski

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