Gambaran Hasil Pemeriksaan Sitologi Cairan Asites di Instalasi Patologi Anatomi RSUD Arifin Achmad Provinsi Riau Periode Januari 2013 – Desember 2017

Ascites is abnormal accumulation fluid in the peritoneal cavity. Many underlying disease can be responsiblefor causing ascites. Peritoneal fluid cytology remains the gold standard for detection of malignant cells inascites which is useful in determining staging, treatment and prognosis. This aim of this study is to describethe characteristic of the result ascitic cytology examination at Anatomical Pathology Department of ArifinAchmad Hospital Period January 2013 – December 2018. This study reviewed the anatomy pathology data.A total of 171 cases consisted of 91.8% were females and males were 8.2%. The highest number caseswere in the age group of 41-50 years (26.9%). Most ascitic fluid came from Department of Obstetric andGynecology (81.9%). The more frequent clinical diagnosis were ovarian carcinoma (19.3%) and ovariancyst (18.7%). Most ascitic cytology examination results was positive cytology (64,9%). Adenocarcinomawas commonest positive cytology (46,2%).

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Ascitic Fluid Cytology Seen in a Tertiary Hospital in Nigeria

Journal of BioMedical Research and Clinical Practice ◽

10.46912/jbrcp.161 ◽

2020 ◽

pp. 345-350

Author(s):

CC Nwafor ◽

K Obioha ◽

TO Akhiwu

Keyword(s):

Sex Ratio ◽

Patient Care ◽

Ascitic Fluid ◽

Age Groups ◽

Tertiary Hospital ◽

Age Group ◽

Malignant Cells ◽

Female Ratio ◽

Male To Female ◽

Fluid Cytology

Ascites is a symptom that can originate due to diverse pathologies. A lot of investigations including ascitic fluid cytology (AFC) can be done on it to help determine its origin. The aim of this study, is to document the findings and highlight the importance of AFC in patient care in Uyo. All AFC reports and slides in the Department of Histopathology, University of Uyo were retrieved, reviewed and used for this study. The age ranged from 1.5 – 80 years with mean age, 41.79 (±17.23) years. About 71.8% of the ascitic fluid (AF) specimens were from patients between the 3rd and 6th decade. Females predominated in all age groups expect 10-19 year's group, with a male to female sex ratio of 1:2.4. Malignant cells were seen in 28.7% of all the samples, while 51.2% were negative for malignant cells. Malignant cells were seen in 4 (6.7%), 11 (18.3%) and 6 (10%) of the AFC performed due to various liver pathologies, ovarian malignancies and intra-abdominal malignancies respectively. Malignant cells were found more in females with a male to female ratio of 1: 3.6. Age group 40-49 years accounted for most of the malignant cases (26.6%). The pattern of AFC in Uyo is similar to the pattern in other parts of Nigeria

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Diagnostic Utility of Cyfra 21-1 and Cea Assays in Pericardial Fluid for the Recognition of Neoplastic Pericarditis

The International Journal of Biological Markers ◽

10.1177/172460080502000107 ◽

2005 ◽

Vol 20 (1) ◽

pp. 43-49 ◽

Cited By ~ 13

Author(s):

M. Szturmowicz ◽

W. Tomkowski ◽

A. Fijalkowska ◽

W. Kupis ◽

A. Cieślik ◽

...

Keyword(s):

Pericardial Effusion ◽

Gold Standard ◽

Pericardial Fluid ◽

Optimal Cutoff ◽

Positive Cytology ◽

Cytological Examination ◽

Malignant Pericardial Effusion ◽

Negative Tumor ◽

Cytology Result ◽

Fluid Cytology

A positive cytology result in pericardial fluid is the gold standard for recognition of malignant pericardial effusion. Unfortunately, in 30–50% of patients with malignant pericardial effusion cytological examination of the pericardial fluid is negative. Tumor marker assessment in pericardial fluid may help to recognize malignant pericardial effusion. The aim of our study was to estimate the value of CYFRA 21-1 and CEA measurement in pericardial fluid for the recognition of malignant pericardial effusion. To our knowledge this is the first study on CYFRA 21-1 assessment in pericardial effusion. The examined group consisted of 50 patients with malignant pericardial effusion and 34 patients with non-malignant pericardial effusion. Median CEA concentrations in malignant pericardial effusion and non-malignant pericardial effusion were 80 ng/mL (0–317) and 0.5 ng/mL (0–18.4), respectively (p<0.001). Median CYFRA 21-1 concentrations in malignant pericardial effusion and non-malignant pericardial effusion were 260 ng/mL (5.3–10080) and 22.4 ng/mL (1.87–317.6), respectively (p<0.001). The optimal cutoff value for CYFRA 21-1 in pericardial effusion was 100 ng/mL. CYFRA 21-1 >100 ng/mL or CEA >5 ng/mL were found in 14/15 patients with malignant pericardial effusion and negative pericardial fluid cytology. We therefore strongly recommend the use of CYFRA 21-1 and/or CEA in addition to pericardial fluid cytology for the recognition of malignant pericardial effusion.

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Cytomorphological study of peritoneal fluid in suspected cases of malignancy

IP Archives of Cytology and Histopathology Research ◽

10.18231/j.achr.2021.046 ◽

2021 ◽

Vol 6 (3) ◽

pp. 206-213

Author(s):

Anchan Vidyashree V ◽

Kanabur Deepak R

Keyword(s):

Predictive Value ◽

Peritoneal Fluid ◽

Descriptive Analysis ◽

Malignant Lesion ◽

Good Method ◽

Accurate Diagnosis ◽

Malignant Cells ◽

Diagnostic Modality ◽

Peritoneal Effusion ◽

Fluid Cytology

Cytology of body fluid is one of the oldest methods that is widely accepted. Though the pleural fluid cytology is well documented, data on peritoneal fluid cytology is sparse. It has a distinct value in confirming or disapproving malignant lesion. Most of the laboratories use cytospin smears for cytological study. While cytospin smears without doubt is a good method for cytodiagnosis, it can be complemented with cellblock for a more accurate diagnosis. Cellblock is a diagnostic modality which can help in pointing the cause for effusion and also in staging, prognosis and therapy of many malignant conditions. The aim of this study is to (1) analyse the cytomorphology of peritoneal fluid using cytospin and cellblock technique and (2) to assess the utility of cellblock method in identifying malignant cells in peritoneal effusion and wash samples. A total of 53 ascitic fluid and peritoneal wash samples that were clinically suspected of malignancy were studied. Each of the samples were processed by cytospin smear and cell block method. The results were interpreted by descriptive analysis. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of the cytological test was 96.15%, 100%, 100%, 96.42% and 98.11% respectively. Cellular yield for malignancy was 3.85% more by the cellblock method. Cellblock can provide an additional information which can aid in increasing the sensitivity of cellblock. It can complement cytospin smears, especially to detect malignant cells in peritoneal fluid. A combined approach of cytospin and cellblock can help in a more accurate diagnosis.

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Significance of cell proliferation markers (Minichromosome maintenance protein 7, topoisomerase IIα and Ki-67) in cavital fluid cytology: Can we differentiate reactive mesothelial cells from malignant cells?

Diagnostic Cytopathology ◽

10.1002/dc.21190 ◽

2009 ◽

pp. NA-NA ◽

Cited By ~ 1

Author(s):

Fumikazu Kimura ◽

Jumpei Kawamura ◽

Jun Watanabe ◽

Shingo Kamoshida ◽

Kenji Kawai ◽

...

Keyword(s):

Cell Proliferation ◽

Mesothelial Cells ◽

Malignant Cells ◽

Minichromosome Maintenance ◽

Topoisomerase Iiα ◽

Ki 67 ◽

Proliferation Markers ◽

Minichromosome Maintenance Protein ◽

Fluid Cytology

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Peritoneal fluid cytology associated with benign neoplastic ovarian tumors in women

American Journal of Obstetrics and Gynecology ◽

10.1016/0002-9378(72)90665-5 ◽

1972 ◽

Vol 113 (7) ◽

pp. 961-966 ◽

Cited By ~ 6

Author(s):

Larry McGowan ◽

Bill Bunnag ◽

Luis B. Arias

Keyword(s):

Peritoneal Fluid ◽

Ovarian Tumors ◽

Fluid Cytology

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A correlation of hysterolaparoscopic findings and BACTEC culture in infertility

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20171404 ◽

2017 ◽

Vol 6 (4) ◽

pp. 1430 ◽

Cited By ~ 1

Author(s):

Mahesweta Guru ◽

Prasad Yeshwant Deshmukh

Keyword(s):

Health Problem ◽

Gold Standard ◽

Semen Analysis ◽

Age Group ◽

Genital Tuberculosis ◽

Infertile Women ◽

Dilatation And Curettage ◽

Important Health ◽

To Come ◽

Sensitive Method

Background: Infertility is agonising condition. Tuberculosis is an important health problem worldwide. One third of the world’s population is currently affected with tuberculosis. Hysterolaparoscopy is a well-recognized procedure for the diagnosis of infertility. Culture for TB bacilli is the gold standard for diagnosis of genital TB.Methods: Infertile women undergoing dilatation and curettage with hysterolaparoscopy with normal husband semen analysis as a part of their infertility workup at M. G. M. Medical Hospital, Kalamboli. Sample size: 30.Results: Incidence of GTB=22.85%, 25-29 year followed by 35-40 years’ age group was the most common age group was observed. In our study, 74.3% infertility pattern was primary, 25.7% were secondary only 2.85 % (n =1) of the cases of GTB were diagnosed by using TB BACTEC. Laparoscopic findings su0ggested that 18 cases had normal findings and 8 cases had laparoscopic features suggestive of GTB. On chromo pertubation, delayed and absent spillage of the dye was seen in 2 cases. On Hysteroscopy, 29 cases (82.9%) of the patients had normal findings and 3 cases had Hysteroscopic features suggestive of GTB.Conclusions: Genital tuberculosis remains an important under diagnosed cause of infertility. Though culture is considered as gold standard for diagnosis of genital tuberculosis, since GTB is paucibacillary there is an urgent need for more research to come to conclusion whether culture is still gold standard. Further research is required to detect the most sensitive method for diagnosis.

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Panoramic radiographs for detecting osteopenia: A pilot study

Clinics and Practice ◽

10.4081/cp.2017.973 ◽

2017 ◽

Vol 7 (4) ◽

Author(s):

Vivek Velayudhan Nair ◽

Sunila Thomas ◽

Jincy Thomas ◽

Cucoo Mariam Mathew

Keyword(s):

Pilot Study ◽

Bone Mass ◽

Gold Standard ◽

Age Group ◽

Low Bone Mass ◽

Panoramic Radiographs ◽

Cortical Index ◽

Mandibular Cortical Index

Osteoporosis characterized by low bone mass/osteopenia can be identified using radiomorphometric indices in routine panoramic radiographs. This study estimates the prevalence of osteopenia in 50-80 years age group, using panoramic mandibular index (PMI), mental index (MI) and mandibular cortical index (MCI). PMI, MI and MCI were applied on 36 panoramic radiographs; MI and MCI were compared with PMI. The prevalence of osteopenia was 11.1% with PMI and 44.4% with MCI. Using MI, the prevalence was 2.8% and 33.3% with 3mm and 4.77mm threshold respectively. The prevalence of osteopenia detected was highest using MCI (44.4%). Considering PMI as gold standard, MI with 4.77 mm threshold showed better agreement with PMI.

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