scholarly journals Symptomatic primary HIV infection in a 49-year-old man who has sex with men: beware of the window phase

2009 ◽  
Vol 14 (48) ◽  
Author(s):  
H E van Oosten ◽  
M Damen ◽  
H JC de Vries

A 49-year-old man with a history of receptive unprotected anal intercourse with multiple anonymous men presented with a symptomatic primary HIV infection. Upon his initial visit the rapid HIV antibody screening test was negative but a p24 antigen test suggested a highly infectious phase in the HIV infection. An immunoblot assay confirmed the HIV diagnosis only 14 days later. Recent infections are characterised by a highly infectious phase and, if gone unnoticed, can have a large contribution to the ongoing transmission of HIV. Healthcare providers should be aware of primary HIV infection and the pitfalls in its diagnosis.

2006 ◽  
Vol 43 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Lydia N Drumright ◽  
Susan J Little ◽  
Steffanie A Strathdee ◽  
Donald J Slymen ◽  
Maria Rosario G Araneta ◽  
...  

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Julian Triebelhorn ◽  
Stefanie Haschka ◽  
Felix Hesse ◽  
Johanna Erber ◽  
Simon Weidlich ◽  
...  

Abstract Background Symptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people following COVID-19 vaccination, can make the diagnosis of acute HIV infection even more challenging. Case presentation A 26-year-old man presented with fever and headache following COVID-19 vaccination. The symptoms were initially thought to be vaccine side effects. A diagnostic workup was conducted due to persisting fever and headache > 72 h following vaccination, and he was diagnosed with Fiebig stage II acute HIV infection, 3 weeks after having unprotected anal intercourse with another man. Conclusion Thorough anamnesis is key to estimating the individual risk of primary HIV infection, in patients presenting with flu-like symptoms. Early diagnosis and initiation of antiretroviral therapy is associated with better prognosis and limits transmission of the disease.


Sexual Health ◽  
2007 ◽  
Vol 4 (3) ◽  
pp. 195 ◽  
Author(s):  
Rebecca Guy ◽  
Megan S. C. Lim ◽  
Yung-Hsuan J. Wang ◽  
Nicholas Medland ◽  
Jonathan Anderson ◽  
...  

Objectives: To establish a new mechanism for monitoring patterns of HIV infection, in the context of a sustained increase in HIV diagnosis among men who have sex with men (MSM) in Victoria. Methods: Between April 2004 and August 2005, a linked voluntary HIV sentinel surveillance system was implemented at five medical clinics with a high case load of MSM. Using a questionnaire, doctors collected HIV testing history, demographic and sexual risk behaviour information from all clients undergoing voluntary HIV testing. Questionnaires were linked with HIV test results. Logistic regression analysis was conducted to determine factors associated with HIV infection. Results: Of 3435 MSM tested for HIV at participating sites, 1.7%, (95% CI = 1.2–2.2) were newly diagnosed with HIV; between 2004 and 2005 the proportion increased from 1.3% (95% CI = 1.2–1.5) to 2.0% (95% CI = 1.8–2.2), P = 0.107. There was no significant change in the number of HIV tests conducted per month or in demographic characteristics, testing history and sexual behaviour characteristics between time periods. In multivariate analysis, reporting unprotected anal intercourse (UAI) with any partner, UAI with a HIV-positive partner/s and being aged 30–39 years or 40 years or greater were significantly associated with HIV infection. Conclusion: This new surveillance mechanism, based on linked testing at participating clinics, indicates that the increase in HIV notifications in 2005 was unrelated to changes in testing and data from a Melbourne sexual behavioural survey suggests the increase was more likely to be attributed to increases in transmission within the past few years. The sentinel system highlighted UAI, especially with HIV positive partner/s are important transmission factors.


2012 ◽  
Vol 6 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Travis Sanchez ◽  
Amanda Smith ◽  
Damian Denson ◽  
Elizabeth DiNenno ◽  
Amy Lansky

Background: Internet-based sampling methods may reach men who have sex with men (MSM) who don’t attend physical venues frequented by MSM and may be at higher risk of HIV infection. Methods: Multivariate logistic regression was used to examine characteristics of adult MSM participants in 2 studies conducted in the same 5 U.S. cities: the 2003-2005 National HIV Behavioral Surveillance System (NHBS) which used sampling from physical MSM venues (e.g., bars, clubs) and the 2007 Web-based HIV Behavioral Surveillance (WHBS) pilot which used sampling through online banner advertisements. Results: Among 5024 WHBS MSM, 95% attended a physical MSM venue in the past 12 months, and 75% attended weekly. WHBS MSM who were black, aged 18-21 years, not college educated, bisexual- or heterosexual-identifying, and reported unknown HIV serostatus were less likely to have attended a physical MSM venue in the past 12 months (all p<0.01). Compared to NHBS MSM, WHBS MSM were more likely to be white, younger, college-educated, report unknown HIV serostatus, report unprotected anal intercourse with a casual partner, and have first met that partner online (all p<0.0001). WHBS MSM were less likely to have been under the influence of drugs during most recent sex (p=0.01) or not know their sex partner’s HIV serostatus (p<0.0001). Conclusions: Many MSM recruited online also attended physical venues, but attendance varied by sub-group. Participants in WHBS and NHBS differed, and WHBS may represent a group of MSM at higher risk of HIV infection. These findings suggest that an internet-based method may be a useful supplement to NHBS.


2021 ◽  
Author(s):  
Julian Triebelhorn ◽  
Stefanie Julia Haschka ◽  
Felix Andreas Hesse ◽  
Johanna Erber ◽  
Simon Weidlich ◽  
...  

Abstract BackgroundSymptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people following COVID-19 vaccination, can make the diagnosis of acute HIV infection even more challenging.Case PresentationA 26-year-old man presented with fever and headache following COVID-19 vaccination. The symptoms were initially thought to be vaccine side effects. A diagnostic workup was conducted due to persisting fever and headache > 72 hours following vaccination, and he was diagnosed with Fiebig stage II acute HIV infection, 3 weeks after having unprotected anal intercourse with another man.ConclusionThorough anamnesis is key to estimating the individual risk of primary HIV infection, in patients presenting with flu-like symptoms. Early diagnosis and initiation of antiretroviral therapy is associated with better prognosis and limits transmission of the disease.


2019 ◽  
Vol 2 (3) ◽  
pp. 32-38
Author(s):  
Lussy Afriyanti ◽  
Agung Waluyo

The current trend of HIV infection shows an increase in cases among men who have sex with men (MSM). Risk behavior in MSM has shown a high prevalence of moderate and worrying risk behaviors for HIV infection, including unprotected anal intercourse (UAI) and drug use. This literature review aims to explore the effectiveness of Personalized Cognitive Counseling (PCC) interventions in reducing risk behaviors for HIV transmission to MSM. Articles discussed in this literature study were obtained from several databases using the keywords “personalized cognitive counseling," “men who have sex with men," and "risk behavior." Cognitive counseling interventions are effective in reducing episodes of anal intercourse. Adapted Personalized Cognitive Counseling (PCC) intervention also has been effective in reducing sexual risk behavior in drug users MSM. This intervention is possible and essential to developing in dealing with risk behavior in MSM that tends to increase in its population.   Keywords: cognitive counseling, personalized cognitive counseling, men who have sex with men (MSM), risk behavior


2007 ◽  
Vol 34 (6) ◽  
pp. 401-407 ◽  
Author(s):  
Lydia N. Drumright ◽  
Steffanie A. Strathdee ◽  
Susan J. Little ◽  
Maria Rosario G. Araneta ◽  
Donald J. Slymen ◽  
...  

2014 ◽  
Vol 44 (2) ◽  
pp. 375-387 ◽  
Author(s):  
Heng Zhang ◽  
Hongyan Lu ◽  
Stephen W. Pan ◽  
Dongyan Xia ◽  
Yuejuan Zhao ◽  
...  

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