scholarly journals Radiologic and clinical features of infection related cytotoxic lesions of corpus callosum splenium in adults

2021 ◽  
Vol 5 (12) ◽  
pp. 1188-1192
Author(s):  
Mehmet Ali İKİDAĞ
2017 ◽  
Vol 47 (6) ◽  
pp. 568-578 ◽  
Author(s):  
Alessia Giuliano ◽  
Irene Saviozzi ◽  
Paolo Brambilla ◽  
Filippo Muratori ◽  
Alessandra Retico ◽  
...  

1997 ◽  
Vol 99 ◽  
pp. S94
Author(s):  
Tetsuhiko Asakura ◽  
Shunichi Yokoyama ◽  
Masaki Nakayama ◽  
Hirofumi Hirano ◽  
Wataru Hirakawa ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Zhiyong Zhang ◽  
Xiufeng Meng ◽  
Wei Liu ◽  
Zunjing Liu

As the largest subcortical commissural fiber, the corpus callosum plays an important role in cerebral functions and has abundant blood supply from bilateral circulation. Isolated corpus callosum infarction (ICCI) may have specific characteristics. The aim of the study is to evaluate the clinical features, etiology, and 6-month prognosis of ICCI. Consecutive patients with acute ICCI treated at the China-Japan Friendship Hospital between June 2012 and June 2016 were retrospectively assessed for clinical and imaging findings. These cases were compared with patients suffering from other isolated supratentorial subcortical infarctions, matched for age, sex, and infarction size (n=60; control group). ICCI etiology and 6-month prognosis were further analyzed. ICCI cases accounted for 2.9% (33/1125) of all acute ischemic strokes and 30 patients were included. Most patients (n=28, 93.3%) presented nonspecific clinical symptoms, and only two (6.7%) with diffuse infarction developed callosal disconnection syndrome (CDS). The splenium was the most frequent site (37.5%). Large artery atherosclerosis (LAA) (n=16, 53.3%) was the most common etiology. Only four (13.3%) patients developed transient ischemic attacks (n=1, 3.3%) or cerebral infarction (n=3, 10%) during the 6-month follow-up. The frequency of good prognosis (modified Rankin score of 1-2 and without cardiovascular events) was higher in patients with ICCI compared with controls (P=0.024). Poor prognosis was associated with multiple cerebrovascular stenosis, diffuse/large infarction, and diabetes (all P<0.05). ICCI is a rare stroke type, frequently involving the splenium; its common etiology is likely LAA. Most patients show nonspecific symptoms, with only a few developing CDS. ICCI generally shows favorable short-term outcome.


1992 ◽  
Vol 34 (5) ◽  
pp. 384-388 ◽  
Author(s):  
D. B. Mendelsohn ◽  
H. S. Levin ◽  
H. Harward ◽  
D. Bruce

2010 ◽  
Vol 68 (1) ◽  
pp. 98-102 ◽  
Author(s):  
Rafael Fabiano Machado Rosa ◽  
Carla Graziadio ◽  
Rene Lenhardt ◽  
Ronnie Peterson Marcondes Alves ◽  
Giorgio Adriano Paskulin ◽  
...  

OBJECTIVE: To describe the central nervous system (CNS) alterations present in a sample of oculo-auriculo-vertebral spectrum (OAVS) patients, trying to correlate them with other clinical features. METHOD: Seventeen patients with diagnosis of OAVS were evaluated. All presented radiological evaluation of the CNS, normal GTG-Banding karyotype and clinical features involving at least two from the four following areas: oro-cranio-facial, ocular, auricular and vertebral. RESULTS: CNS alterations were verified in eight from seventeen patients (47%). Diffuse cerebral hypoplasia, dilated lateral cerebral ventricles (asymptomatic hydrocephalus), corpus callosum dysgenesis and frontal hypodensities were the most frequent abnormalities. Presence of ophthalmologic abnormalities was the only clinical association observed, being significantly more frequent among patients with cerebral alterations (63% versus 11%). CONCLUSION: CNS abnormalities are frequent in patients with OAVS, especially in carriers of ophthalmologic alterations. However, the absence of detectable cerebral abnormalities did not exclude the possibility that these subjects will subsequently present neurological symptoms.


2020 ◽  
Author(s):  
Yun Zhang ◽  
Bin Qin ◽  
Longlun Wang ◽  
Ke Zhang ◽  
Cui Song ◽  
...  

Abstract Background: Gender differences in clinical features is a prominent feature of autism spectrum disorder (ASD), and the corpus callosum (CC) is the largest commissural tract connecting the left and right hemispheres associated with autism symptoms. This study aimed to analyze the relationship between gender-associated clinical features and CC size in children aged 2-4 years.Methods: A prospective study of 100 children aged 2-4 years, including 50 cases with ASD (ASD group) and 50 cases with typically developing (TD group) who were matched with equivalent samples of ASD, were recruited with assessments of demographic data (gender, age, and body mass index [BMI]), clinical features (full-scale/verbal/performance IQ, ADOS, and ADI-R), and CC size measured by Structural Magnetic Resonance Imaging. SPSS version 22 was used to analyze the data.Results: The mid-posterior CC (MPCC), anterior-middle CC (AMCC), and total CC (TCC) volumes in ASD were higher than that in TD, and the significance these sub-regions volumes between ASD-Females and ASD-Males was existed in ASD group (all P < 0.05). Analogously, the mean of verbal IQ score in ASD-Males was significantly higher than in ASD-Females, but the scores of ADOS communication (AC) and ADOS total (AT) were lower in ASD-Males (all P < 0.05). AC and AT scores were significantly and positively related to MPCC, AMCC and TCC volumes (all P < 0.05), but verbal IQ score was significantly and negatively associated with MPCC, AMCC and TCC volumes (all P < 0.05). In ASD-Males and -Females, both AC and AT scores increase with the change of MPCC, AMCC and TCC volumes, but VIQ decline.Conclusion: The language ability, including communication and verbal IQ, of ASD aged 2-4 years old has gender differences, which may be related to the CC size, especially the MPCC and AMCC.


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