Conventional and Microwave Assisted Synthesis with Antimicrobial Evaluation of Novel Pyrrolidine Molecule: An Approach to Easy Synthetic Pathway

2018 ◽  
Vol 8 (2) ◽  
pp. 298-303
Author(s):  
K Sreekanth ◽  
Anjali Jha
2018 ◽  
Vol 55 (12) ◽  
pp. 2744-2759 ◽  
Author(s):  
Serap Basoglu Ozdemir ◽  
Neslihan Demirbas ◽  
Ahmet Demirbas ◽  
Faik Ahmet Ayaz ◽  
Nesrin Çolak

2011 ◽  
Vol 8 (1) ◽  
pp. 305-311 ◽  
Author(s):  
Priyanka Kamaria ◽  
N. Kawathekar ◽  
Prerna Chaturvedi

In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by takingDMFas solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized byIR,1HNMRand mass spectral analysis. All compounds were tested against five gram positive and five gram negative bacterial strains and one fungal strain. All compounds exhibited better activity against gram positive strains than against gram negative strains and the compounds were found more active againstS.aureusandB.subtilis.


2017 ◽  
Vol 22 (1) ◽  
pp. 57-70 ◽  
Author(s):  
Dongamanti Ashok ◽  
Srinivas Gundu ◽  
Vikas Kumar Aamate ◽  
Mohan Gandhi Devulapally

2018 ◽  
Vol 63 (2) ◽  
pp. 3918-3923
Author(s):  
S Pazhinivel Sakthinathan ◽  
Ramamoorthy Suresh ◽  
Dakshnamoorthy Kamalakkannan ◽  
Veerandiran Mala ◽  
Kaliyan Sathiyamoorthi ◽  
...  

2019 ◽  
Vol 70 (9) ◽  
pp. 3094-3099 ◽  
Author(s):  
Emilian Georgescu ◽  
Florea Dumitrascu ◽  
Florentina Georgescu ◽  
Constantin Draghici ◽  
Denisa Dumitrescu

A library of new pyrrolo[1,2-c]quinazoline derivatives was obtained by the one-pot, three-component microwave-assisted synthesis, starting from quinazolines, 2-bromoacetyl derivatives and electron-deficient alkynes in 1,2-epoxybutane via 1,3-dipolar cycloaddition of quinazolinium N-ylides. This synthetic pathway offers a simple and rapid access to a large range of pyrrolo[1,2-c]quinazoline derivatives.


2019 ◽  
Vol 84 (3) ◽  
pp. 237-244
Author(s):  
Dongamanti Ashok ◽  
Rangu Kavitha ◽  
Srinivas Gundu ◽  
Madderla Sarasija

A new series of 6-[3-aryl-1-phenyl-4?,5?-dihydro[4,5?-bi-1H-pyrazol]-3?-yl]-2H-chromen-5-ol derivatives was synthesized by Michael addition of chalcones 5a?j with hydrazine hydrate in presence of sodium acetate under conventional heating and microwave irradiation. Structural assignment of the products was confirmed based on IR, 1H-NMR, 13C-NMR, MS and analytical data. All the synthesized compounds 6a?j were screened for their antimicrobial activity against various bacterial and fungal strains. Most of the compounds exhibited variable range of antimicrobial activity and compounds 6c?f and 6i showed promising antimicrobial potency.


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