THE ROLE OF ?-HEMOLYTIC STREPTOCOCCUS GROUP B IN PRETERM MEMBRANE RUPTURE

Radicular cysts are, most often, oral tissue cysts. The basis for their development are the remains of Hertwig's epithelial sheath, which is stimulated to proliferate by infectious agents, mostly periapical granuloma or pulp necrosis. The cyst contents can be liquid, either clear or milky-white, or thick and yellowish-caseous pus. Bacteriological and histopathological researches have shown that development of radicular cysts from periapical lesions is a consequence of penetration of normal bacterial flora of the oral cavity. Material and methods The study has bacteriologically examined contents of 50 radicular cysts. They were operated between 1993 and 1995 at the Department of Oral Surgery of the Outpatient Health Care Centre Banjaluka. Pathological substrate of the cyst was punctured by a sterile needle and bacteriologically examined at the Microbiological Laboratory of the Clinical Centre in Banjaluka. Discussion and conclusion Radicular cysts contents most often consisted of alpha-hemolytic streptococcus, Streptococcus pneumoniae, Staphyilococcus epidermidis, Streptococcus group B and alpha-hemolytic Streptococcus. It is concluded that normal oral cavity flora is present in the cysts contents the infection penetrated through the root canal to periapex, where, due to the course of time, radicular cyst develops from periapical granuloma.

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Bacterial Infection in Newborns with Respiratory Distress: The Role of Group B β-Hemolytic Streptococcus (GBS) in Brazilian Newborns. 1333

Pediatric Research ◽

10.1203/00006450-199704001-01352 ◽

1997 ◽

Vol 41 ◽

pp. 225-225

Author(s):

Rivianny A. Nobre ◽

Marisa M. Mussi-Pinhata ◽

Francisco E. Martinez ◽

Salim M. Jorge ◽

Arthur L. Goncalves ◽

...

Keyword(s):

Respiratory Distress ◽

Bacterial Infection ◽

Hemolytic Streptococcus ◽

Group B

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Skin Lesions in Association With β-Hemolytic Streptococcus Group B

PEDIATRICS ◽

10.1542/peds.58.6.859 ◽

1976 ◽

Vol 58 (6) ◽

pp. 859-861

Author(s):

Juan B. Lopez ◽

Paul Gross ◽

Thomas R. Boggs

Keyword(s):

Caesarean Section ◽

Male Infant ◽

Skin Lesions ◽

In Utero ◽

Full Term ◽

Hemolytic Streptococcus ◽

Streptococcus Group ◽

Healing Phase ◽

Group B ◽

Amniotic Membranes

A full-term male infant delivered by caesarean section following a prolonged rupture of the amniotic membranes of 30 hours' duration manifested peculiar skin lesions at the time of birth consistent with the healing phase of bullous impetigo. He was colonized with β-hemolytic Streptococcus group B that was also cultured from the mother's cervix. It is possible this infant became infected in utero since the healing stage of the lesions suggest that they were present sometime before birth.

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Group B Streptococcal Infection in Infancy: A Case Report and Review

PEDIATRICS ◽

10.1542/peds.38.4.659 ◽

1966 ◽

Vol 38 (4) ◽

pp. 659-661

Author(s):

ERNEY MAHER ◽

ROBERT C. IRWIN

Keyword(s):

Case Report ◽

Pregnant Women ◽

Successful Treatment ◽

Low Birthweight ◽

Streptococcal Infection ◽

Neonatal Morbidity ◽

Hemolytic Streptococcus ◽

Streptococcus Group ◽

Initial Symptoms ◽

Group B

A case of meningitis and septicemia due to hemolytic streptococcus group B in a 42-day-old, low birthweight infant has been presented. The increasing evidence of danger to the newborn from this organism has been discussed. The fulminant progression of the meningitic infection from initial symptoms to death leaves little hope for successful treatment. The practice of eradicating asymptomatic streptococcal B organisms from birth canals of pregnant women is proposed as a possible measure for reducing neonatal morbidity and mortality.

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Beta hemolytic streptococcus Group B associated with problems of the perinatal period

American Journal of Obstetrics and Gynecology ◽

10.1016/s0002-9378(16)36146-4 ◽

1961 ◽

Vol 82 (4) ◽

pp. 809-818 ◽

Cited By ~ 148

Author(s):

Marion Hood ◽

Ailleen Janney ◽

George Dameron

Keyword(s):

Perinatal Period ◽

Hemolytic Streptococcus ◽

Streptococcus Group ◽

Beta Hemolytic Streptococcus ◽

Group B

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Tissue Ki67 proliferative index expression and pathological changes in hemodialysis arteriovenous fistulae: Preliminary single-center results

The Journal of Vascular Access ◽

10.1177/11297298211015495 ◽

2021 ◽

pp. 112972982110154

Author(s):

Raffaella Mauro ◽

Cristina Rocchi ◽

Francesco Vasuri ◽

Alessia Pini ◽

Anna Laura Croci Chiocchini ◽

...

Keyword(s):

Morphological Changes ◽

Hot Spot ◽

Wall Thickening ◽

Proliferating Cells ◽

Ki 67 ◽

Group A ◽

The Mean ◽

Set Up ◽

Group B

Background: Arteriovenous fistula (AVF) for hemodialysis integrates outward remodeling with vessel wall thickening in response to drastic hemodynamic changes. Aim of this study is to determine the role of Ki67, a well-established proliferative marker, related to AVF, and its relationship with time-dependent histological morphologic changes. Materials and methods: All patients were enrolled in 1 year and stratified in two groups: (A) pre-dialysis patients submitted to first AVF and (B) patients submitted to revision of AVF. Morphological changes: neo-angiogenesis (NAG), myointimal thickening (MIT), inflammatory infiltrate (IT), and aneurysmatic fistula degeneration (AD). The time of AVF creation was recorded. A biopsy of native vein in Group A and of arterialized vein in Group B was submitted to histological and immunohistochemical (IHC) analysis. IHC for Ki67 was automatically performed in all specimens. Ki67 immunoreactivity was assessed as the mean number of positive cells on several high-power fields, counted in the hot spots. Results: A total of 138 patients were enrolled, 69 (50.0%) Group A and 69 (50.0%) Group B. No NAG or MIT were found in Group A. Seven (10.1%) Group A veins showed a mild MIT. Analyzing the Group B, a moderate-to-severe MIT was present in 35 (50.7%), IT in 19 (27.5%), NAG in 37 (53.6%); AD was present in 10 (14.5%). All AVF of Group B with the exception of one (1.4%) showed a positivity for Ki67, with a mean of 12.31 ± 13.79 positive cells/hot spot (range 0–65). Ki67-immunoreactive cells had a subendothelial localization in 23 (33.3%) cases, a myointimal localization in SMC in 35 (50.7%) cases. The number of positive cells was significantly correlated with subendothelial localization of Ki67 ( p = 0.001) and with NA ( p = 0.001). Conclusions: Native veins do not contain cycling cells. In contrast, vascular cell proliferation starts immediately after AVF creation and persists independently of the time the fistula is set up. The amount of proliferating cells is significantly associated with MIT and subendothelial localization of Ki67-immunoreactive cells, thus suggesting a role of Ki-67 index in predicting AVF failure.

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High Basal Maximal Standardized Uptake Value (SUVmax) in Follicular Lymphoma Identifies Patients with a Low Risk of Long-Term Relapse

Cancers ◽

10.3390/cancers13122876 ◽

2021 ◽

Vol 13 (12) ◽

pp. 2876

Author(s):

Giovanni Manfredi Assanto ◽

Giulia Ciotti ◽

Mattia Brescini ◽

Maria Lucia De Luca ◽

Giorgia Annechini ◽

...

Keyword(s):

Risk Factors ◽

Follicular Lymphoma ◽

Standardized Uptake Value ◽

Metabolic Tumor Volume ◽

Late Relapse ◽

Prognostic Role ◽

Pet Ct ◽

Group A ◽

Group B

Background: Despite that the unfavorable prognostic role of a high Total Metabolic Tumor Volume (TMTV) in Follicular Lymphoma has been demonstrated, the role of SUVmax alone at baseline PET/CT could have a different prognostic role. Patients and Methods: We performed a retrospective observational monocentric cohort study. All patients affected by FL who underwent a basal PET/CT were included. Two subgroups were identified and compared in terms of PFS and OS: (A) Basal SUVmax ≤ 6; and (B) Basal SUVmax > 6. Results: Ninety-four patients were included, 34 in group A (36.2%) and 60 in group B (63.8%). The PFS at two years was comparable in the two groups (97%). The five-year PFS was 73.5% for group A and 95% for group B (p 0.005). The five-year PFS in the whole cohort was 87.5%. A clear advantage was confirmed in group A in the absence of other risk factors. Patients with SUVmax ≤ 6 and no risk factors showed a 5-year PFS of 73% against 83% for patients with SUVmax > 6 and at least two risk factors. Conclusion: A high FDG uptake favorably correlated with PFS. A low basal SUVmax reflected a higher rate of late relapse requiring a prolonged follow-up. The basal SUVmax is an approachable parameter with prognostic implications.

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