scholarly journals Adenoid cystic carcinoma of the breast: case report

Mastology ◽  
2021 ◽  
Vol 31 ◽  
Author(s):  
Matheus Lavigne Marinho ◽  
Alexandre Tafuri ◽  
Carlos Alberto da Silva Ramos ◽  
Antônio Alexandre Lisbôa Ladeia ◽  
Luciana de Carvalho Azevedo
Keyword(s):  
Breast Cancer ◽  
Adenoid Cystic Carcinoma ◽  
Triple Negative ◽  
Breast Conserving Surgery ◽  
Genetic Alterations ◽  
Good Prognosis ◽  
Carcinoma Of The Breast ◽  
Adenoid Cystic ◽  
Molecular Aspects ◽  
Peculiar Behavior

Adenoid cystic carcinoma (AdCC) of the breast is an uncommon invasive lobular neoplasm whose morphology is similar to the homonymous tumor of salivary glands and with a peculiar behavior toward the “triple-negative” (TN) profile. Tumors belonging to this family do not immunohistochemically express three of the main prognostic biomarkers and tend to show a more aggressive behavior. However, this rare histological pattern of breast cancer is generally associated with good prognosis. In this study, the authors describe the case of a 49-year-old woman diagnosed with this rare malignant tumor and who underwent breast-conserving surgery. Recent studies have aimed to understand the genes, genetic alterations, and etiological aspects related to the still obscure etiopathogenesis of AdCC. Thus, morphological and molecular aspects relevant to AdCC and reported in the literature will be discussed.

Adenoid cystic carcinoma of the breast: a triple negative breast cancer with a special guideline

The Breast ◽  
2019 ◽  
Vol 44 ◽  
pp. S117-S118
Author(s):  
A.-S. Rotsaert ◽  
K. Watty ◽  
C. Inge ◽  
K. Schotte ◽  
W. Tjalma
Keyword(s):  
Breast Cancer ◽  
Adenoid Cystic Carcinoma ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Carcinoma Of The Breast ◽  
Adenoid Cystic

scholarly journals Adenoid cystic carcinoma: triple negative breast cancer with good prognosis

2016 ◽  
pp. bcr2015213704 ◽  
Author(s):  
Daniel Romeira ◽  
Débora Cardoso ◽  
Helena Miranda ◽  
Ana Martins
Keyword(s):  
Breast Cancer ◽  
Adenoid Cystic Carcinoma ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Good Prognosis ◽  
Adenoid Cystic

scholarly journals Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer

2016 ◽  
Vol 29 (11) ◽  
pp. 1292-1305 ◽  
Author(s):  
Nicola Fusco ◽  
Felipe C Geyer ◽  
Maria R De Filippo ◽  
Luciano G Martelotto ◽  
Charlotte K Y Ng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adenoid Cystic Carcinoma ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
High Grade ◽  
Carcinoma Of The Breast ◽  
Adenoid Cystic ◽  
Genetic Events

scholarly journals Adenoid cystic carcinoma of the breast: case report and review of literature

2012 ◽  
Vol 94 (4) ◽  
pp. e137-e138 ◽  
Author(s):  
R Veeratterapillay ◽  
S Veeratterapillay ◽  
E Ward ◽  
H Khout ◽  
T Fasih
Keyword(s):  
Case Report ◽  
Adenoid Cystic Carcinoma ◽  
Rare Condition ◽  
Good Prognosis ◽  
Treatment Modalities ◽  
Review Of Literature ◽  
Breast Lump ◽  
Carcinoma Of The Breast ◽  
Adenoid Cystic

We report the case of a patient who presented with a painful breast lump that turned out to be an adenoid cystic carcinoma of the breast. The literature is reviewed, highlighting the good prognosis associated with this rare condition and the current preferred treatment modalities.

scholarly journals Discovery of Biomarkers Predictive of GSI Response in Triple-Negative Breast Cancer and Adenoid Cystic Carcinoma

2014 ◽  
Vol 4 (10) ◽  
pp. 1154-1167 ◽  
Author(s):  
Alexander Stoeck ◽  
Serguei Lejnine ◽  
Andrew Truong ◽  
Li Pan ◽  
Hongfang Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adenoid Cystic Carcinoma ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Adenoid Cystic

MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas

2013 ◽  
Vol 154 (25) ◽  
pp. 963-968 ◽  
Author(s):  
Orsolya Kiss ◽  
Anna-Mária Tőkés ◽  
Sándor Spisák ◽  
Anna Szilágyi ◽  
Norbert Lippai ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Clinical Outcome ◽  
Adenoid Cystic Carcinoma ◽  
Mirna Expression Profile ◽  
Good Prognosis ◽  
Normal Breast ◽  
Carcinoma Of The Breast ◽  
Adenoid Cystic ◽  
Tumor Tissues ◽  
Post Transcriptional Regulation

Introduction: Adenoid cystic carcinoma is a salivary gland-derived malignant tumor, but rarely it can originate from the breast, too. The salivary gland-derived form shows a very aggressive clinical outcome, while adenoid cystic carcinoma of the breast has mostly a very good prognosis. Aim: The aim of the authors was to compare the miRNA-expression profile of breast- and salivary gland-derived cases. Method: The miRNA-profiles of two salivary gland derived and two breast-derived adenoid cystic carcinoma tissues as well as one normal breast and one salivary gland tissues were analysed using the Affymetrix® Gene Chip. Results: The expression of some miRNAs differed in the tumor tissues compared to their controls: the let-7b was overexpressed in salivary gland-derived adenoid cystic carcinoma, while decreased in breast-derived adenoid cystic carcinoma. In addition, the miR-24 was decreased in salivary gland-derived but overexpressed in breast-derived adenoid cystic carcinomas. The miR-181a-2* was only detected in salivary gland-derived adenoid cystic carcinomas. Conclusions: Through post-transcriptional regulation of the genes, the diverse expression of some miRNAs may partially explain the diverse clinical outcome of salivary gland-derived and breast-derived adenoid cystic carcinomas. Orv. Hetil., 2013, 154, 963–968.

scholarly journals Adenoid Cystic Carcinoma of the Breast: A Rare Histopathology- Good Prognosis

2013 ◽  
Vol 46 (1) ◽  
pp. 39-41
Author(s):  
Onur Esbah ◽  
Ahmet Siyar Ekinci ◽  
Emine Benzer ◽  
Tahsin Ozatli ◽  
Berna Oksuzoglu
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Good Prognosis ◽  
Carcinoma Of The Breast ◽  
Adenoid Cystic

Breast Cancer in Young Women

2019 ◽  
Author(s):  
Lisa A Newman
Keyword(s):  
Breast Cancer ◽  
Young Women ◽  
Triple Negative ◽  
Breast Conserving Surgery ◽  
The United States ◽  
Population Based ◽  
Incidence Rates ◽  
Disease Stage ◽  
Locoregional Therapy ◽  
Key Words Breast

The perception that breast cancer in young women is a growing problem in the United States is based on the fact that young women represent a demographic that has enlarged substantially over the past few decades. Population-based data actually reveal relatively stable incidence rates for breast cancer among women in the premenopausal age range. Young women are more likely to be diagnosed with biologically aggressive phenotypes such as triple-negative and HER2/neu-overexpressing breast cancer. Outcomes are optimized by treatment plans focusing on disease stage and targeted to phenotype. Locoregional therapy for breast cancer in young women should be based on patient preferences and disease pattern (as in older patients); young women with breast cancer can be managed safely with breast-conserving surgery. This review contains 3 figures, 2 tables, and 50 references. Key Words: breast cancer, fertility, ovarian suppression, premenopausal, young women; triple negative breast cancer

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