A late diagnosis of secondary hemochromatosis was made to a 38-year-old man with chronic hepatitis B, who after poisoning with alcohol surrogate (which was a year ago) had episodes of macrohematuria with signs of acute kidney damage, which required treatment in the ICU and hemodialysis sessions, after which kidney function was restored. In August 2020, the patient had a contact with a COVID-19 patient, but upon admission to the hospital, the results of tests for COVID-19 were negative. During the examination in our department, after the exclusion of the urological disease, the diagnosis of interstitial nephritis of toxic etiology, hemolytic anemia, chronic viral hepatitis B was made. Then in-depth study of iron metabolism, bone marrow, and MRI of parenchymal organs revealed secondary hemochromatosis.