scholarly journals URINARY TRACT INFECTION

2011 ◽  
Vol 18 (03) ◽  
pp. 466-469
Author(s):  
GHULAM HUSSAIN BALOCH ◽  
MUKHTIAR HUSSAIN JAFFERY ◽  
CHANDRA MADHUDAS ◽  
Bikha Ram Devrajani ◽  
Syed Zulfiquar Ali Shah

Objective: To determine the frequency and pattern of urinary tract infection in patients with diabetes mellitus. Design: Descriptive case series study. Period: February 2009 to July 2009. Setting: Department of medicine at Liaquat University Hospital). Patients and methods: All patients ≥18 years of age, of either gender were known diabetes for ≥ 2 years duration. The infection was labeled when >5/hpf leukocyte in urine and growth of organism on urine for C/S. The blood sugar and hemoglobin A1C (HbA1C) was also advised to evaluate the status of their diabetes i.e. control or poorly control. Result: During study period total 150 diabetic patients were evaluated for urinary tract infection, of which 92(61%) had UTI. Out of ninety two 80(87%) had diabetes type 2 and 12(13%) were diabetes type 1. The female gender was predominant. The mean ± SD for age of patients with type 2 and type 1 diabetes mellitus was 53.52±10.74 and 20.77±1.65 whereas the mean random blood sugar level in patients with type 2 and 1 diabetes was 232.85±5.87 and 288.99 ± 7.87. The mean ± SD for duration of diabetes type 2 and 1 was 4.77±2.31 and 2.56±1.42. The isolated microorganism were Staphylococcus aureus, Escherichia coli, Proteus, Pseudomonas aeruginosa, Klebsiella, Enterobacteriaceae and C.albicans. Conclusions: The urinary tract infection is more prevalent in patients with diabetes mellitus.

2014 ◽  
Vol 18 (2 (70)) ◽  
Author(s):  
O. A. Olenovych

According to the results of complex assessment of integral haematological coefficients the development of endogenous intoxication was revealed in case of diabetes mellitus, whose intensity depends on the type of the disease and causes immune system disorganization. The decrease of functional activity of specific immunity as well as nonspecific one in case of diabetes mellitus leads to deregulation of cellular and humoral reactions and depends on diabetes type: in diabetes type 1 the reduction of nonspecific immunoresistance is contributed by microphages, in diabetes type 2 – by macrophages, accompanied by the deficiency of specific immune defense, reliably more significant in diabetes type 2.


2022 ◽  
pp. 138-142
Author(s):  
N. V. Sturov ◽  
S. V. Popov ◽  
I. Yu. Shmelkov

Introduction. In recent years, the role of fungal infection in inpatient and outpatient patients has been increasing. At the same time, there are currently no recommendations on the duration of treatment of outpatient patients with fungal urinary tract infection (UTI). Aim of the study. Optimization of methods of diagnosis and treatment of outpatient patients with fungal UTI.Materials and methods. To detect fungi in urine, the E. Koneman et al. (1997) method was improved. 56 patients with fungal UTI were examined. The efficacy of fluconazole in the treatment of fungal UTI was studied in 53 patients.Results. Candida albicans was detected in 37% of cases of fungal UTI in outpatient patients. Risk factors for fungal UTI in outpatient patients include: antibacterial therapy, infravesical obstruction, type 2 diabetes mellitus and the presence of urinary drainage. The microbiological efficacy of fluconazole therapy for 7, 10 and 14 days was 83.0%, 94.3% and 96.2%, respectively. The growth of fungi in the urine a month after treatment was absent in 86.7% of patients. In outpatient patients with fungal UTI without type 2 diabetes mellitus, the efficacy of fluconazole at a dose of 150 mg per day for 7 days was 94.9%. In patients with type 2 diabetes mellitus after 7 days of therapy, the efficacy was 50.0%.Conclusions. The most common causative agent of fungal UTI in outpatient patients is Candida albicans. To detect fungi in urine, samples should be seeded on selective media, while increasing the seeding volume to 0.1 ml and extending the incubation time to 96 hours. Fluconazole is a highly effective treatment for fungal UTI at a dose of 150 mg per day for 7 days, however, in patients with diabetes mellitus, therapy should last at least 10 days.


2001 ◽  
Vol 53 (3) ◽  
pp. 181-186 ◽  
Author(s):  
R. Goswami ◽  
C.S. Bal ◽  
S. Tejaswi ◽  
G.V. Punjabi ◽  
A. Kapil ◽  
...  

2012 ◽  
Vol 77 (01) ◽  
pp. 40-48 ◽  
Author(s):  
Reinhard Fünfstück ◽  
Lindsay E. Nicolle ◽  
Markolf Hanefeld ◽  
Kurt G. Naber

2020 ◽  
Vol Volume 13 ◽  
pp. 1961-1970
Author(s):  
Fatemeh Saheb Sharif-Askari ◽  
Narjes Saheb Sharif-Askari ◽  
Adnane Guella ◽  
Ali Alabdullah ◽  
Hour Bashar Al Sheleh ◽  
...  

2020 ◽  
Vol 41 (10) ◽  
pp. 1181-1189
Author(s):  
Felix W. A. Waibel ◽  
Martin C. Berli ◽  
Viviane Gratwohl ◽  
Kati Sairanen ◽  
Dominik Kaiser ◽  
...  

Background: The contralateral foot in Charcot arthropathy or neuroarthropathy (CN) is subject to increased plantar pressure. To date, the clinical consequences of this pressure elevation are yet to be determined. The aim of this study was to evaluate ulcer and amputation rates of the contralateral foot in CN. Methods: We abstracted the medical records of 130 consecutive subjects with unilateral CN. Rates of contralateral CN development and recurrence, contralateral ulcer development, and contralateral amputations were recorded. Statistical analysis was performed to identify possible risk factors for contralateral CN and ulcer development, and contralateral amputation. Mean follow-up was 6.2 (SD 4) years. Results: After a mean of 2.5 years, 19.2% patients developed contralateral CN. Female gender was associated with contralateral CN development (odds ratio 3.13, 95% confidence interval 1.27, 7.7). Overall, 46.2% patients developed a contralateral ulcer. Among the patients who developed contralateral CN, 60% developed an ulcer. Sanders type 2 at the index foot (midfoot CN) was significantly associated with contralateral ulcer development. Ulcer-free survival (UFS) differed significantly between patients with diabetes type 1 (median UFS 5131 days) and patients with diabetes type 2 (median UFS 2158 days). A total of 25 amputations had to be performed in 22 (16.9%) patients. Three of those 22 patients (2.3%) needed major amputation. Conclusion: Almost 20% of patients developed contralateral CN. Nearly half of people with CN developed a contralateral foot ulceration. Patients with type 2 diabetes had significantly shorter UFS than patients with diabetes type 1. Every sixth patient needed an amputation, with the majority being minor amputations. The contralateral foot should be monitored closely and included in the treatment in patients with CN. Level of Evidence: Level IV, retrospective study.


Author(s):  
Amin Kordi yoosefinejad ◽  
Farzaneh Moslemi Haghighi

Background: Diabetes is a highly significant public health problem inIran with a prevalence of 5 to 8%. Proprioception plays an important role in the orientation and limb movement in space. Diabetic neuropathy decreases sensory function and causes gait instabilities.Objective: The present study evaluated knee proprioception and kinesthesia in patients with type 2 diabetes with and without neuropathy and compared the results with those of healthy people. Methods: The subjects were ten type 2 diabetes mellitus patients with diabetes type 2 associated with neuropathy, ten patients with diabetes without neuropathy and ten healthy people as the control group. Data were collected in a physical examination and using a questionnaire. Special tests included manual muscle testing of the knee musculature, Achilles and patellar reflexes, and knee proprioception and kinesthesia. Data were analyzed using one-way ANOVA and the Tukey test.Results: the results show that knee proprioception and kinesthesia were significantly decreased in patients with diabetes mellitus type 2 in comparison with healthy people and there was a greater decline in patients with diabetes associated with neuropathy than in patients with diabetes without neuropathy. Also, knee musculature strength was significantly lower in patients with diabetes in comparison with healthy people and the attenuation was greater in neuropathic patients than in non-neuropathic ones. Conclusions: Patients with diabetes type 2 especially those with neuropathy suffer from proprioception deficits. Proprioception training may prevent secondary problems occurring as a result of proprioception impairment in patients with diabetes type2.


2017 ◽  
Vol 69 (3) ◽  
pp. 2133-2136 ◽  
Author(s):  
Faisal Abdullah Alrwithey ◽  
Abdullah Eid Ayyadah Alahmadi ◽  
AliMohammed Fayez Alshehri

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