scholarly journals Factors affecting In-patient stay in patients operated for peptic ulcer perforation.

2020 ◽  
Vol 27 (10) ◽  
pp. 2076-2080
Author(s):  
Talha Kareem ◽  
Ali Rabbani ◽  
Sana Ahmad Khan ◽  
Muhammad Hamid Chaudhary ◽  
Muhammad Farrukh Aftab ◽  
...  
Keyword(s):  
Risk Factors ◽  
Peptic Ulcer ◽  
Hospital Stay ◽  
Cross Sectional Study ◽  
Pulmonary Complications ◽  
Peptic Ulcer Perforation ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Ulcer Perforation ◽  
Patient Stay

Objectives: Recognizing the risk factors affecting the in-hospital stay of the patients operated for peptic ulcer perforation. Study Design: Cross Sectional study. Setting: General Surgical Wards, Nishtar Hospital Multan. Period: From 15th November 2018 to 5th of March 2019. Material & Methods: A total of 100 patients of all ages who had a peptic ulcer perforation were included. Patients with a perforation that wasn't attributable to a peptic ulcer e.g. malignancy or gastrinoma were excluded. Patients were asked about their smoking and drinking habits. Data was collected about various risk factors of peptic ulcer, their co-morbidities and the medications. Results: Gender, smoking, alcohol intake, H-pylori infection, size & site of perforation did not have a significant effect on hospital stay days. In patient stay days differed in groups based on comorbidities and medication. A weak correlation was found among age and stay days. Conclusion: Patients with complain of COPD and other pulmonary complications have a longer hospital stay in the hospital. The association of arthritis and hypertension could not be demonstrated comprehensively.

scholarly journals Correlation Between Candidiasis And Mortality In Gastric Ulcer Perforation Patients

2021 ◽  
Vol 5 (11) ◽  
pp. 1037-1041
Author(s):  
Faradina Sulistiyani ◽  
Vicky Sumarki Budipramana ◽  
Pepy Dwi Endraswari
Keyword(s):  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
General Hospital ◽  
Gastrointestinal Disease ◽  
Perforated Peptic Ulcer ◽  
Cross Sectional Study ◽  
Peptic Ulcer Perforation ◽  
Cross Sectional ◽  
Ulcer Disease ◽  
Ulcer Perforation

Background: Gastric ulcer disease remains the most common gastrointestinal disease. This affects about 4 million people every year worldwide with an incidence of 1.5%-3% and 2-14% of these will progress to perforation. Mortality is reported in 30% of cases and caused morbidity in 50% of patients. Some studies have suggested that mortality in patients with peritonitis accompanied by candidiasis ranges from 20%-75%, whereas others have argued that the presence of fungal isolates in patients with perforated peptic ulcer does not affect the outcome. A recent study reported an incidence of 45% of patients peptic ulcer perforation cases accompanied by candidiasis in Dr. Soetomo General Hospital Surabaya in 2019.Methods: This was a cross sectional study based on medical record data of patients with gastric ulcer perforation accompanied by candidiasis who underwent laparotomy and gastric repair surgery at Dr. Soetomo General Hospital Surabaya from January 2019 to December 2020.Results: There was no significant correlation between candidiasis and mortality in gastric ulcer perforation patients (p=0.989).Conclusion: Candidiasis does not increase mortality in patients with gastric ulcer perforation.

scholarly journals Correlation Between Candidiasis And Mortality In Gastric Ulcer Perforation Patients

2021 ◽  
Vol 5 (4) ◽  
pp. 947-952
Author(s):  
Faradina Sulistiyani ◽  
Vicky Sumarki Budipramana ◽  
Pepy Dwi Endraswari
Keyword(s):  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
General Hospital ◽  
Gastrointestinal Disease ◽  
Perforated Peptic Ulcer ◽  
Cross Sectional Study ◽  
Peptic Ulcer Perforation ◽  
Cross Sectional ◽  
Ulcer Disease ◽  
Ulcer Perforation

Background: Gastric ulcer disease remains the most common gastrointestinal disease. This affects about 4 million people every year worldwide with an incidence of 1.5%-3% and 2-14% of these will progress to perforation. Mortality is reported in 30% of cases and caused morbidity in 50% of patients. Some studies have suggested that mortality in patients with peritonitis accompanied by candidiasis ranges from 20%-75%, whereas others have argued that the presence of fungal isolates in patients with perforated peptic ulcer does not affect the outcome. A recent study reported an incidence of 45% of patients peptic ulcer perforation cases accompanied by candidiasis in Dr. Soetomo General Hospital Surabaya in 2019.Methods: This was a cross sectional study based on medical record data of patients with gastric ulcer perforation accompanied by candidiasis who underwent laparotomy and gastric repair surgery at Dr. Soetomo General Hospital Surabaya from January 2019 to December 2020.Results: There was no significant correlation between candidiasis and mortality in gastric ulcer perforation patients (p=0.989).Conclusion: Candidiasis does not increase mortality in patients with gastric ulcer perforation.

scholarly journals Analysis of risk factors affecting the development of peptic ulcer perforation: case-control study

2020 ◽  
Author(s):  
Sami Akbulut ◽  
Ali Caliskan ◽  
Hasan Saritas ◽  
Khaled Demyati ◽  
Yilmaz Bilgic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Peptic Ulcer ◽  
Case Control Study ◽  
Case Control ◽  
Peptic Ulcer Perforation ◽  
Factors Affecting ◽  
Ulcer Perforation ◽  
Control Study

RISK FACTORS AFFECTING PEPTIC ULCER PERFORATION

2021 ◽  
pp. 11-14
Author(s):  
Ketan Patel ◽  
Harshit Agarwal ◽  
Jitendra K. Mangtani ◽  
Neelkamal Gupta
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Peptic Ulcer ◽  
Posterior Wall ◽  
Peptic Ulcer Perforation ◽  
Factors Affecting ◽  
Ulcer Disease ◽  
Ulcer Perforation ◽  
Operative Outcome ◽  
Perforation Peritonitis

Introduction: Peptic ulcer is a sore in the lining of stomach or the rst part of the duodenum. Peptic ulcer perforation with subsequent peritonitis is commonest complication of peptic ulcer disease and is a surgical emergency. It carries with it great morbidity and mortality. AIMS: To study the risk factors associated with peptic ulcer perforation in our setting. Objectives: To Assess the role of various risk factors like age, sex, previous use of NSAIDS, Smoking & other associated illness. To study the risk factors that affect operative outcome in peptic perforation peritonitis. Materials & Methods: All patients of peptic ulcer with perforation peritonitis on laparotomy are included in the study.Patients with peptic ulcer Perforation of age > 14 years. Results: Duodenal perforations were present In 69 cases out of 100 cases (69%). Gastric perforation was present in 31 cases (31%). In gastric cases 30 perforations were present on lesser curvature and pyloric Antrum and one perforation was present on posterior wall of stomach. Discussion: Present clinical study of peptic perforation has been carried out to nd out various risk factor associated with It's occurrence, investigation, clinical picture, preoperative ndings and post operative outcome and recurrence of perforation after taking Anti H. pylori regime was observed. Conclusion:In my study that H.pylori infection, smoking, use of NSAID's is signicant risk factor on peptic perforation

A CROSS-SECTIONAL STUDY TO PREVALENCE OF HELICOBACTER PYLORI IN PEPTIC ULCER PERFORATION AT DMCH, LAHERIASARAI, BIHAR

2021 ◽  
pp. 4-5
Author(s):  
Ravindra Ravindra ◽  
Vijay Shankar Prasad ◽  
Debarshi Jana
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Perforated Peptic Ulcer ◽  
Cross Sectional Study ◽  
Peptic Ulcer Perforation ◽  
Sectional Study ◽  
Cross Sectional ◽  
Ulcer Disease ◽  
Ulcer Perforation ◽  
H Pylori

Background: Helicobacter pylori have an important role in the pathogenesis of peptic ulcer disease. The aim of the present study was to observe the prevalence of H. pylori in peptic ulcer perforation cases and the rationale of H. pylori eradication therapy post operatively and to investigate factors associated with peptic ulcer. Methods: This cross-sectional study was conducted at the Upgraded Department of Surgery, Darbhanga Medical College & Hospital, Laheriasarai, Bihar. A total of 113 patients were participated in the study after meeting inclusion criteria. After getting written consent from the patients with perforated peptic ulcer, resuscitation and laparotomy was performed in the emergency department. H. pylori infection was conrmed by histopathological examination by Giemsa staining. Based on the histopathological report, the prevalence of H. pylori infection in the patients was assessed and was given appropriate H. pylori eradication regimen. Results: The mean age of presentation of the patients was 52.81±14.5 years. Male to female ratio was 4.14:1. Out of 113 cases, 67 cases (59.3%) had duodenal ulcer perforation while 46 cases (40.7%) had gastric ulcer perforation. Of them 53(46.9%) cases were positive H. pylori positive. No signicant association was found between the incidence of H. pylori infection in peptic ulcers with smoking, hypertension, diet intake, NSAIDS intake. In our study association between H. pylori and diabetes mellitus (p=0.02) found to be signicant which can be further investigated. Conclusion: According to our study the prevalence of H. pylori infection in perforated peptic ulcer disease is 47% which must be considered as signicant. Hence all the patients undergoing laparotomy for peptic ulcer perforation should be investigated for H. pylori infection and if positive we must start the anti H. pylori regimen for them, which is more cost effective.

scholarly journals Peptic perforations: comparative study of its closure (omentopexy versus figure of 8 closure)

2019 ◽  
Vol 6 (6) ◽  
pp. 2074
Author(s):  
Sanjay Changole ◽  
Maheshkumar Soni ◽  
Dattatray Thakare
Keyword(s):  
Risk Factors ◽  
Peptic Ulcer ◽  
Hospital Stay ◽  
Recovery Time ◽  
Surgical Techniques ◽  
Postoperative Recovery ◽  
Wound Complications ◽  
Peptic Ulcer Perforation ◽  
Burst Abdomen ◽  
Ulcer Perforation

Background: Peptic ulcer perforation is one the most common and catastrophic maladies that affect mankind. The aim of this study was to compare the surgical techniques of peptic ulcer perforation closure namely omentopexy and figure of 8 stitch with reference to recovery time and complications rate.Methods: Of 80 selected patients, figure of 8 method for closure of peptic perforation was used in 40 patients and 40 by using omentopexy method. Outcomes were compared in view of postoperative recovery time and postoperative complications such as wound complications, respiratory complications, burst abdomen, septicaemia, hospital stay, death.Results: In our study it was noted that age of presentation was in elderly males with risk factors like alcohol, smoking, tobacco chewing, and NSAIDS use in decreasing order. Late presentation was associated with higher complication including one death. In figure of 8 group it was found that RT Removal was early, early oral resumption loss hospital stay in figure of 8 group than in omentopexy group. Complications such as wound complication, burst abdomen , leak, and septicaemia  were more in omentopexy group than figure of 8 group. Only one death occurred in study that was in omentopexy group.Conclusions: We came to conclusion that peptic perforation is more common in males around 50 years with risk factors of smoking and alcohol. Outcomes of surgery with figure of 8 stitch were better than omentopexy with respect to oral resumptions, early discharge, less complications such as wound complications, burst abdomen leak septicaemia and death.

scholarly journals Risk Factors that Affect Morbidity and Mortality in Patients with Perforated Peptic Ulcer Diseases in a Teaching Hospital

2020 ◽  
Vol 30 (4) ◽  
Author(s):  
Nebyou Seyoum ◽  
Daba Ethicha ◽  
Zelalem Assefa ◽  
Berhanu Nega
Keyword(s):  
Risk Factors ◽  
Peptic Ulcer ◽  
Addis Ababa ◽  
Previous History ◽  
Perforated Peptic Ulcer ◽  
Cross Sectional Study ◽  
Morbidity And Mortality ◽  
Delayed Presentation ◽  
Cross Sectional ◽  
Female Ratio

Background: This study was done to identify risk factors that affect the morbidity and mortality of patients operated for a perforated peptic ulcer in a resource-limited setting.Methods: A two years (January 1, 2016 - December 30, 2018) retrospective cross- sectional study was done on patients admitted and operated for PPU at Yekatit 12 Hospital, Addis Ababa,Ethiopia.Results: A total of 93 patients were operated. The median age affected was 29 years (Range 15-75 years). Male to female ratio was 7.5:1. Chewing chat, smoking and alcohol use were seen in 22 (23.6%), 35(37.6%), and 34(36.5%), cases respectively. Only 23.6% gave previous history of dyspepsia. The median duration of illness was 48hours and the duodenal to gastric ulcer perforation ratio was 6.5:1. In majority of the cases (63.3%) the perforation diameter was <10mm (63.3%). Cellan-Jones repair of the perforations was done in 92.5% of cases. A total of 47 complications were seen in 25 cases. The total complications and mortality rates were 25(26.8%) and 6(6.5%) respectively. The most common postoperative complication was pneumonia (13.97%) followed by superficial surgical site infection (10.8%). Mortality rate was highest among patients >50yrs [AOR (95%CI) =2.4(2-30)]. Delayed presentation of >24 hours [AOR (95%CI) =4.3(1.4-13.5)] and a SBP <90mmhg [AOR (95%CI) =4.8(1-24)] were found to be significantly related with higher complication rate.Conclusions: Patients who presented early and immediate corrective measures were instituted had better outcomes while those seen late developed unfavorable out-come with significantly higher complications. Therefore, early detection and treatment of PPU is essential.

scholarly journals Association of Helicobacter Pylori with Peptic Ulcer Perforation

2019 ◽  
Vol 2 (1) ◽  
pp. 4-10
Author(s):  
Sunit Agrawal ◽  
D Thakur ◽  
P Kafle ◽  
A Koirala ◽  
R K Sanjana ◽  
...  
Keyword(s):  
Risk Factors ◽  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Perforated Peptic Ulcer ◽  
Patch Repair ◽  
Peptic Ulcer Perforation ◽  
Ulcer Disease ◽  
Ulcer Perforation ◽  
H Pylori

Background: Helicobacter pylori is found in more than 90% cases of peptic ulcer. This study examines the possibility of association of Helicobacter pylori in perforated peptic ulcer disease and its relation to persisting ulcer as well as the influence of other risk factors; namely: smoking, alcohol, current non-steroidal anti inflammatory drugs (NSAIDs) and steroid use. Materials and Methods: In this prospective study, total of 50 cases of peptic ulcer perforation admitted in College of Medical Sciences and Teaching Hospital, Bharatpur, Nepal were selected on the basis of the non-probability (purposive) sampling method. All patients who presented with suspected peptic ulcer perforation were included in the study and the perforations were repaired by Modified Graham’s Patch and were given triple therapy postoperatively. The age, sex, incidence, mode of presentation, precipitating factors, association with the risk factors and postoperative complications were all evaluated and compared. Results: Of 50 patients studied, the age ranged from 17 to 75 years, mean age being 40.1 years with the peak incidence in the 3rd and 5th decades of life showing a male dominance (92%). H. pylori was seen in ulcer edge biopsy in 29 patients (58%). Most common clinical presentation was pain abdomen, the most common signs of perforation were tenderness, rebound tenderness and absent bowel sounds. The mean duration of stay in hospital in H. pylori positive patients was 12.07±8.15 days as compared with 11.1±5.12 days in H. pylori negative patients. The incidence of peptic ulcer perforation was higher in the patients consuming alcohol (64%) than smokers (48%), followed by NSAIDs user(22%). 20% of the patients with delayed presentation developed complications postoperatively. Perforated peptic ulcer was repaired by Modified Graham’s Patch Repair, followed by anti H. pylori therapy in all of them. Conclusion: Peptic ulcer perforation is quite common among the patients with peptic ulcer disease with history of chronic smoking, alcoholism and analgesic intake, more commonly in males. There is association of H. pylori in 58% of patients with peptic ulcer perforation.

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