scholarly journals The Diverticular Disease Registry (DDR Trial) by the Advanced International Mini-Invasive Surgery Academy Clinical Research Network: Protocol for a Multicenter, Prospective Observational Study

2021 ◽  
Vol 25 (1) ◽  
pp. 194-200
Author(s):  
Matteo Origi ◽  
Pietro Achilli ◽  
Giacomo Calini ◽  
Andrea Costanzi ◽  
Michela Monteleone ◽  
...  
Keyword(s):  
Observational Study ◽  
Clinical Research ◽  
Diverticular Disease ◽  
Invasive Surgery ◽  
Prospective Observational Study ◽  
Network Protocol ◽  
Research Network ◽  
Disease Registry ◽  
Clinical Research Network ◽  
Multicenter Prospective Observational Study

scholarly journals Ultra-Response to Ranibizumab: Improvement by 4 or More Steps in Diabetic Retinopathy Severity in Diabetic Retinopathy Clinical Research Network Protocol S

2020 ◽  
Author(s):  
Allen Chiang ◽  
Sunir J. Garg ◽  
Michael A. Klufas ◽  
Allen C. Ho ◽  
Lauren Hill ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Clinical Research ◽  
Network Protocol ◽  
Research Network ◽  
Clinical Research Network

scholarly journals Creation of a rectal cancer registry in Italy by the Advanced International Mini-Invasive Surgery (AIMS) academy clinical research network

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1736
Author(s):  
Giulio M. Mari ◽  
Pietro Achilli ◽  
Dario Maggioni ◽  
Jacopo Crippa ◽  
Andrea T.M. Costanzi ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Data Collection ◽  
Clinical Research ◽  
Cancer Registry ◽  
Invasive Surgery ◽  
High Volume ◽  
Research Network ◽  
Quality Data ◽  
Curative Intent ◽  
Clinical Research Network

Background: The management of rectal cancer is multimodal and involves a multidisciplinary team of cancer specialists with expertise in medical oncology, surgical oncology, radiation oncology and radiology. It is crucial for highly specialized centers to collaborate via networks that aim to maintain uniformity in every aspect of treatment and rigorously gather patients’ data, from the first clinical evaluation to the last follow-up visit. The Advanced International Mini-Invasive Surgery (AIMS) academy clinical research network aims to create a rectal cancer registry. This will prospectively collect the data of patients operated on for non-metastatic rectal cancer in high volume colorectal surgical units through a well design pre-fashioned database for non-metastatic rectal cancer, in order to take all multidisciplinary aspects into consideration. Methods/Design: The protocol describes a multicenter prospective observational cohort study, investigating demographics, frailty, cancer-related features, surgical and radiological parameters, and oncological outcomes among patients with non-metastatic rectal cancer who are candidates for surgery with curative intent. Patients enrolled in the present registry will be followed up for 5 years after surgery. Discussion: Standardization and centralization of data collection for neoplastic diseases is a virtuous process for patient care. The creation of a register will allow the control of the quality of treatments provided and permit prospective and retrospective studies to be carried out on complete and reliable high quality data. Establishing data collection in a prospective and systematic fashion is the only possibility to preserve the enormous resource that each patient represents.

This month at the NIH: NIDDK forms hepatotoxicity clinical research network

2003 ◽  
Vol 125 (4) ◽  
pp. 1008-1008
Author(s):  
Stephen P. James
Keyword(s):  
Clinical Research ◽  
Research Network ◽  
Clinical Research Network

Endoscope‐assisted transoral accessory parotid mass excision: Multicenter prospective observational study

2019 ◽  
Vol 130 (5) ◽  
pp. 1218-1226 ◽  
Author(s):  
Jin Pyeong Kim ◽  
Dong Kun Lee ◽  
Jeong Hwan Moon ◽  
Jun Sun Ryu ◽  
Seung Hoon Woo
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Multicenter Prospective Observational Study

scholarly journals Eye Tumors in Childhood as First Sign of Tumor Predisposition Syndromes: Insights from an Observational Study Conducted in Germany and Austria

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1876
Author(s):  
Madlen Reschke ◽  
Eva Biewald ◽  
Leo Bronstein ◽  
Ines B. Brecht ◽  
Sabine Dittner-Moormann ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Observational Study ◽  
Ciliary Body ◽  
Prospective Observational Study ◽  
Genetic Data ◽  
Detailed History ◽  
Cancer Early Detection ◽  
Physical Examinations ◽  
Eye Tumors ◽  
Multicenter Prospective Observational Study

Retinoblastoma and other eye tumors in childhood are rare diseases. Many eye tumors are the first signs of a genetic tumor predisposition syndrome and the affected children carry a higher risk of developing other cancers later in life. Clinical and genetic data of all children with eye tumors diagnosed between 2013–2018 in Germany and Austria were collected in a multicenter prospective observational study. In five years, 300 children were recruited into the study: 287 with retinoblastoma, 7 uveal melanoma, 3 ciliary body medulloepithelioma, 2 retinal astrocytoma, 1 meningioma of the optic nerve extending into the eye. Heritable retinoblastoma was diagnosed in 44% of children with retinoblastoma. One child with meningioma of the optic nerve extending into the eye was diagnosed with neurofibromatosis 2. No pathogenic constitutional variant in DICER1 was detected in a child with medulloepithelioma while two children did not receive genetic analysis. Because of the known association with tumor predisposition syndromes, genetic counseling should be offered to all children with eye tumors. Children with a genetic predisposition to cancer should receive a tailored surveillance including detailed history, physical examinations and, if indicated, imaging to screen for other cancer. Early detection of cancers may reduce mortality.

24‐hour fluid administration in emergency department patients with suspected infection; a multicenter, prospective, observational study

2021 ◽  
Author(s):  
Marie Kristine Jessen ◽  
Lars Wiuff Andersen ◽  
Marie‐Louise Holm Thomsen ◽  
Marie Egebjerg Jensen ◽  
Mathilde Emilie Kirk ◽  
...  
Keyword(s):  
Emergency Department ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Fluid Administration ◽  
Suspected Infection ◽  
Multicenter Prospective Observational Study ◽  
Emergency Department Patients
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