Umbilical Artery Blood Acid-Base and Blood Gas Status Following Uncomplicated Term Vaginal Deliveries in Japanese Newborn Infants.

We performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical artery. Based on 1st and 5th minutes Apgar scores, 40 (88.9%) and 21 babies (46.7%}, respectively, had asphyxia. Relation to acid-base balance was determined with the sensitivity of the 5th minute Apgar score in predicting acidotic states. It was found that Apgar score had sensitivity of 57.7% and specificity of 68.4% in predicting the acidotic states. Apgar score of > 7 was unable to. exclude the possible acidosis in 45% of cases (negative predictive value 54.1%). Gestational age had no influence on Apgar Scores. Apgar score was more sensitive to eliminate suspected acidosis in term neonates than in preterms. We recommend to perform umbilical arterial blood gas analysis to determine acidotic state in high risk newborn infants.

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Maternal arterial blood values during delivery: effect of mode of delivery, maternal characteristics, obstetric interventions and correlation to fetal umbilical cord blood

10.1101/2020.02.14.950089 ◽

2020 ◽

Author(s):

Mehreen Zaigham ◽

Sara Helfer ◽

Karl Heby Kristensen ◽

Per-Erik Isberg ◽

Nana Wiberg

Keyword(s):

Vaginal Delivery ◽

Epidural Anesthesia ◽

Umbilical Cord Blood ◽

Mode Of Delivery ◽

Blood Gas ◽

Acid Base ◽

Maternal Characteristics ◽

Arterial Blood ◽

Vaginal Deliveries ◽

Synthetic Oxytocin

AbstractObjectiveTo determine a reference interval for maternal arterial blood values during vaginal delivery and to elucidate the effect of common maternal characteristics and obstetric interventions on maternal acid base values during vaginal and planned cesarean section (CS).DesignProspective, observational study of randomly selected women undergoing vaginal deliveries and planned CS at Skåne University Hospital, Malmö, Sweden.ResultsTwo hundred and fifty women undergoing vaginal delivery (VD) and fifty-eight women undergoing planned CS were recruited. We found significant differences for gestational age, parity, artery pH, pCO2, pO2, sO2 and cord venous pH, pCO2 and lactate between the two study groups (P < 0.005). For women undergoing vaginal delivery, we found significant changes in base deficit, hemoglobin, bilirubin, potassium, glucose and lactate values as compared to women with planned CS (P < 0.02). Maternal characteristics did not significantly affect acid base parameters however, multiple regression showed significant associations for the use of epidural anesthesia on maternal pH (P < 0.05) and pO2 (P < 0.01); and synthetic oxytocin on pCO2 (P = 0.08), glucose (P < 0.00) and lactate (P < 0.02) in maternal blood. Maternal arterial pH, pCO2 and lactate correlated significantly to values in venous umbilical cord blood (P < 0.000).ConclusionsReference values for maternal arterial blood gases in vaginal deliveries for term pregnancies were outlined and we found that most arterial blood gas parameters varied significantly according to mode of delivery. The use of different obstetrical interventions like epidural anesthesia or synthetic oxytocin, resulted in significant changes in blood gas values.

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Interpretation of the impact parameter of acid-base status and electrolytes in blood gas analysis in the pulmonary system using artificial intelligence techniques

Computer Science and Systems Engineering ◽

10.2495/csse140691 ◽

2015 ◽

Author(s):

E. Beganović ◽

Z. Avdagić ◽

S. Omanović

Keyword(s):

Artificial Intelligence ◽

Impact Parameter ◽

Blood Gas Analysis ◽

Gas Analysis ◽

Blood Gas ◽

Acid Base ◽

Artificial Intelligence Techniques ◽

Pulmonary System ◽

Acid Base Status ◽

The Impact

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UMBILICAL VESSEL ANGIOCARDIOGRAPHY IN THE NEWBORN INFANT

PEDIATRICS ◽

10.1542/peds.31.6.946 ◽

1963 ◽

Vol 31 (6) ◽

pp. 946-951

Author(s):

Samuel O. Sapin ◽

Leonard M. Linde ◽

George C. Emmanouilides

Keyword(s):

Newborn Infant ◽

Umbilical Artery ◽

Umbilical Vein ◽

Newborn Infants ◽

Umbilical Vessel ◽

Accurate Interpretation ◽

Sick Newborn

Angiocardiography from an umbilical vessel approach was performed in 10 critically sick newborn infants. The umbilical vein route was successfully employed up to the eighth day of life, while the umbilical artery was safely used as late as age 5 days. This approach has advantages over other methods of catheterization and angiocardiography. Angiocardiographic quality was satisfactory for accurate interpretation.

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Acid-Base Balance and Blood Gas Interpretation

Surgical Intensive Care Medicine ◽

10.1007/978-1-4757-6645-5_8 ◽

2001 ◽

pp. 131-146

Author(s):

M. Fareed Azam ◽

William T. Peruzzi

Keyword(s):

Blood Gas ◽

Acid Base Balance ◽

Acid Base ◽

Base Balance

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Vasomotion induces regular major oscillations in jejunal mucosal tissue oxygenation

AJP Gastrointestinal and Liver Physiology ◽

10.1152/ajpgi.1994.266.6.g978 ◽

1994 ◽

Vol 266 (6) ◽

pp. G978-G986 ◽

Cited By ~ 3

Author(s):

W. Hasibeder ◽

R. Germann ◽

H. Sparr ◽

M. Haisjackl ◽

B. Friesenecker ◽

...

Keyword(s):

Tissue Oxygenation ◽

Jejunal Mucosa ◽

Blood Gas ◽

Acid Base ◽

Oxygen Extraction Ratio ◽

Physiological Basis ◽

Midline Laparotomy ◽

Jejunal Segment ◽

Hemoglobin Saturation ◽

The Mean

The mucosa of the small intestine has some unique microcirculatory features that may result in significant tissue oxygenation changes even under physiological conditions. To prove this hypothesis we investigated mucosal and serosal oxygenation in an autoperfused, innervated jejunal segment in pigs. Eight animals (30-40 kg) were anesthetized, paralyzed, and normoventilated. A small segment of the jejunal mucosa and serosa was exposed by a midline laparotomy and an antimesenteric incision. Mucosal and serosal oxygen tensions were measured using Clark-type surface oxygen electrodes. Mucosal hemoglobin saturation and concentration were determined by tissue reflectance spectrophotometry. Systemic hemodynamics, mesenteric-venous acid base, and blood gas variables, as well as systemic acid-base and blood gas variables and jejunal electromyogenic potentials, were recorded. Measurements were performed after a rest period at 0, 30, 60, and 90 min. All animals remained hemodynamically stable. At time 0 the jejunal oxygen extraction ratio was 0.33 +/- 0.05, the mean serosal PO2 was 60.25 +/- 7.69, the mean mucosal PO2 was 25.47 +/- 4.41 mmHg, and the mean mucosal hemoglobin saturation was 46.36 +/- 6.22%. Mean values did not change with time. In contrast to serosal PO2, mucosal PO2, mucosal hemoglobin oxygen saturation, and hemoglobin concentration showed rhythmic oscillations with a frequency of 3.4-5 cycles/min that were unrelated to systemic hemodynamic parameters, respiratory frequency, and intestinal peristalsis. From this we concluded that the jejunal mucosa demonstrates significant, regular changes in oxygenation parameters that are locally mediated. We speculate that the physiological basis for this phenomenon is the countercurrent arrangement of microvessels in conjunction with vasomotion.(ABSTRACT TRUNCATED AT 250 WORDS)

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Blood-Gas and Acid–Base Parameters in Nontranquilized Arabian Oryx (Oryx leucoryx) in the United Arab Emirates

Journal of Zoo and Wildlife Medicine ◽

10.1638/2006-0025.1 ◽

2008 ◽

Vol 39 (1) ◽

pp. 6-12 ◽

Cited By ~ 7

Author(s):

Conor Kilgallon ◽

Tom Bailey ◽

Barbara Arca-Ruibal ◽

Martha Misheff ◽

Declan O'Donovan

Keyword(s):

United Arab Emirates ◽

Blood Gas ◽

Acid Base ◽

Base Parameters ◽

Arabian Oryx

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Umbilical Cord Blood Gas Analysis, Obstetric Performance and Perinatal Outcome

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0038-1675187 ◽

2018 ◽

Vol 40 (12) ◽

pp. 740-748 ◽

Cited By ~ 1

Author(s):

Cátia Ferreira ◽

Ângela Melo ◽

Ana Fachada ◽

Helena Solheiro ◽

Nuno Nogueira Martins

Keyword(s):

Umbilical Cord Blood ◽

Apgar Score ◽

Umbilical Artery ◽

Blood Gas Analysis ◽

Gas Analysis ◽

Blood Gas ◽

Neonatal Hypoxia ◽

Total Cohort ◽

Group A ◽

Minute Apgar Score

Objective To analyze if umbilical artery pH (pHua) ≤7.00 and umbilical artery blood deficit (BDua) ≥12.00 mmol/L are good predictors of adverse neonatal outcomes. Methods This was an observational, longitudinal and retrospective cohort study, conducted at the department of obstetrics and gynecology of Centro Hospitalar Tondela Viseu between September 2013 and September 2015. Total cohort and subgroup analysis were performed: group A—women with umbilical cord blood gas analysis (UCBGA) performed for non-reassuring fetal cardiotocographic patterns, placental abruption, or shoulder dystocia; and group B—all the others. Assays were made with the software SPSS for Windows, Versions 20.0 and 21.0 (IBM Corp., Armonk, NY, USA). Results A total of 428 UCBGAs met the inclusion criteria. The group analysis revealed an association between group A and pHua ≤7.00, as well as between BDua ≥12.00 mmol/L and 1st minute Apgar score ≤4 (p = 0.011). After the application of the logistic regression models in the total cohort analysis, pHua ≤7.00 had an impact in the occurrence of acute neonatal hypoxia (odds ratio [OR]: 6.71; 95% confidence interval [CI]: 1.21–37.06; p = 0.029); multiparous women had a higher risk of delivering a newborn with first minute Apgar score ≤4 and acute neonatal hypoxia (OR: 5.38; 95% CI: 1.35–21.43; p = 0.017; and OR: 2.66; 95% CI: 1.03–6.89, p = 0.043, respectively); women who had urologic problems during pregnancy had a higher risk of delivering a newborn with 5th minute Apgar score ≤7 (OR: 15.17; 95% CI: 1.29–177.99; p = 0.030); and shoulder dystocia represented a 15 times higher risk of acute neonatal hypoxia (OR: 14.82; 95% CI: 2.20–99.60; p = 0.006). Conclusion The pHua and the BDua are predictors of adverse neonatal outcome, and UCBGA is a useful tool for screening newborns at risk. Universal UCBGA should be considered for all deliveries, as it is an accurate screening test for neonatal hypoxia.

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