iPrevent: Engaging youth as long-acting HIV prevention product co-researchers in Cape Town, South Africa

2021 ◽  
Vol 20 (4) ◽  
pp. 277-286
Author(s):  
Miriam Hartmann ◽  
Alexandra M Minnis ◽  
Emily Krogstad ◽  
Sheily Ndwayana ◽  
Siyaxolisa Sindelo ◽  
...  
Keyword(s):  
South Africa ◽  
Hiv Prevention ◽  
Cape Town ◽  
Long Acting

“It’s natural to look for a source”: A qualitative examination of alternative beliefs about HIV and AIDS in Cape Town, South Africa

2015 ◽  
Vol 26 (3) ◽  
pp. 369-384 ◽  
Author(s):  
Clara Rubincam
Keyword(s):  
South Africa ◽  
Hiv Prevention ◽  
Focus Group ◽  
Scientific Evidence ◽  
Cape Town ◽  
Hiv And Aids ◽  
Men And Women ◽  
Street Level ◽  
Outright Rejection ◽  
Past Experiences

This article highlights how African men and women in South Africa account for the plausibility of alternative beliefs about the origins of HIV and the existence of a cure. This study draws on the notion of a “street-level epistemology of trust”—knowledge generated by individuals through their everyday observations and experiences—to account for individuals’ trust or mistrust of official claims versus alternative explanations about HIV and AIDS. Focus group respondents describe how past experiences, combined with observations about the power of scientific developments and perceptions of disjunctures in information, fuel their uncertainty and skepticism about official claims. HIV prevention campaigns may be strengthened by drawing on experiential aspects of HIV and AIDS to lend credibility to scientific claims, while recognizing that some doubts about the trustworthiness of scientific evidence are a form of skeptical engagement rather than of outright rejection.

scholarly journals Outcomes of a community-based HIV-prevention pilot programme for township men who have sex with men in Cape Town, South Africa

2013 ◽  
Vol 16 ◽  
pp. 18754 ◽  
Author(s):  
Elizabeth Batist ◽  
Benjamin Brown ◽  
Andrew Scheibe ◽  
Stefan D Baral ◽  
Linda-Gail Bekker
Keyword(s):  
South Africa ◽  
Hiv Prevention ◽  
Cape Town ◽  
Community Based ◽  
Pilot Programme ◽  
Sex With Men

The influence of male circumcision for HIV prevention on sexual behaviour among traditionally circumcised men in Cape Town, South Africa

2011 ◽  
Vol 22 (11) ◽  
pp. 674-679 ◽  
Author(s):  
L A Eaton ◽  
D N Cain ◽  
A Agrawal ◽  
S Jooste ◽  
N Udemans ◽  
...  
Keyword(s):  
South Africa ◽  
Hiv Prevention ◽  
Male Circumcision ◽  
Sexual Behaviour ◽  
Risk Perceptions ◽  
Cape Town ◽  
Sexual Partners ◽  
Health Clinic ◽  
Risk Compensation ◽  
Vaginal Sex

We examined the relationship between HIV prevention beliefs related to male circumcision and sexual behaviour/sexually transmitted infection (STI) acquisition among traditionally circumcised men in Cape Town, South Africa. HIV-negative men (n = 304), circumcised for cultural/religious reasons, attending a health clinic in Cape Town, South Africa, completed cross-sectional surveys. Generalized linear models were used to analyse the relationships between unprotected vaginal sex acts, number of female sexual partners, STI diagnoses and male circumcision-related beliefs and risk perceptions. Men who were aware that circumcision offers protection against HIV (relative risk [RR] = 1.19, 95% confidence interval [CI] = 1.06-1.32, P < 0.01), endorsed risk compensation related to male circumcision (RR = 1.15, 95% CI = 1.11-1.12, P < 0.01) and perceived lower risk of HIV infection when circumcised (RR = 1.08, 95% CI = 1.04-1.12, P < 0.01) were more likely to report unprotected vaginal sex acts. Similar patterns were also identified when predicting number of female sexual partners. Men who were more likely to endorse risk compensation related to male circumcision were also more likely to be diagnosed with a chronic STI (odds ratio [OR] = 1.64, 95% CI = 1.06-2.53, P < 0.05). Our findings suggest that we must not overlook the effects of beliefs towards male circumcision for HIV prevention among men traditionally circumcised; doing so may undermine current efforts to reduce HIV transmission through male circumcision.

scholarly journals Adaptation and validation of simple tools to screen and monitor for oral PrEP adherence

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251823
Author(s):  
Seth Zissette ◽  
Elizabeth E. Tolley ◽  
Andres Martinez ◽  
Homaira Hanif ◽  
Katherine Gill ◽  
...  
Keyword(s):  
South Africa ◽  
Clinical Trials ◽  
Factor Analysis ◽  
Hiv Prevention ◽  
Construct Validity ◽  
Screening Tool ◽  
Cape Town ◽  
Original Sample ◽  
Monitoring Tool ◽  
Oral Prep

Introduction Oral, vaginal and other pre-exposure prophylaxis (PrEP) products for HIV prevention are in various stages of development. Low adherence poses a serious challenge to successful evaluation in trials. In a previous study, we developed tools to screen for general adherence and specifically monitor intravaginal ring adherence within the context of HIV prevention clinical trials. This study aimed to further validate the screening tool and to adapt and provide initial psychometric validation for an oral pill monitoring tool. Materials and methods We administered a cross-sectional survey between June and October 2018 at a trial site located near Cape Town, South Africa, and another in Thika, Kenya, with 193 women who had experience using daily oral pills. We fit confirmatory factor analysis models on the screening tool items to assess our previously-hypothesized subscale structure. We conducted an exploratory factor analysis of oral PrEP monitoring items to determine the underlying subscale structure. We then assessed the construct validity of each tool by comparing subscales against each other within the current sample and against our original sample, from a study conducted in four sites in South Africa, including Cape Town. Results The screening tool structure showed moderate evidence of construct validity. As a whole, the tool performed in a similar way to the original sample. The monitoring tool items, which were revised to assess perceptions about and experiences using daily oral PrEP, factored into five subscales that showed moderate to good reliability. Four of the five subscales had a similar structure overall to the vaginal ring monitoring tool from which they were adapted. Conclusions Accurate measurement of HIV-prevention product adherence is of critical importance to the assessment of product efficacy and safety in clinical trials, and the support of safe and effective product use in non-trial settings. In this study, we provide further validation for these measures, demonstrating the screening tool’s utility in additional populations and adapting the monitoring tool’s utility for different HIV-prevention products.

scholarly journals A community-based mobile clinic model delivering PrEP for HIV prevention to adolescent girls and young women in Cape Town, South Africa

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Elzette Rousseau ◽  
Linda-Gail Bekker ◽  
Robin F. Julies ◽  
Connie Celum ◽  
Jennifer Morton ◽  
...  
Keyword(s):  
South Africa ◽  
Hiv Prevention ◽  
Adolescent Girls ◽  
Young Women ◽  
Scale Up ◽  
Cape Town ◽  
Sub Saharan Africa ◽  
Health Clinic ◽  
Community Based ◽  
Depth Interviews

Abstract Background Daily doses of pre-exposure prophylaxis (PrEP) can reduce the risk of acquiring HIV by more than 95 %. In sub-Saharan Africa, adolescent girls and young women (AGYW) are at disproportionately high risk of acquiring HIV, accounting for 25 % of new infections. There are limited data available on implementation approaches to effectively reach and deliver PrEP to AGYW in high HIV burden communities. Methods We explored the feasibility and acceptability of providing PrEP to AGYW (aged 16–25 years) via a community-based mobile health clinic (CMHC) known as the Tutu Teen Truck (TTT) in Cape Town, South Africa. The TTT integrated PrEP delivery into its provision of comprehensive sexual and reproductive health services (SRHS). We analyzed data from community meetings and in-depth interviews with 30 AGYW PrEP users to understand the benefits and challenges of PrEP delivery in this context. Results A total of 585 young women started PrEP at the TTT between July 2017 – October 2019. During in-depth interviews a subset of 30 AGYW described the CMHC intervention for PrEP delivery as acceptable and accessible. The TTT provided services at times and in neighborhood locations where AGYW organically congregate, thus facilitating service access and generating peer demand for PrEP uptake. The community-based nature of the CMHC, in addition to its adolescent friendly health providers, fostered a trusting provider-community-client relationship and strengthened AGYW HIV prevention self-efficacy. The integration of PrEP and SRHS service delivery was highly valued by AGYW. While the TTT’s integration in the community facilitated acceptability of the PrEP delivery model, challenges faced by the broader community (community riots, violence and severe weather conditions) also at times interrupted PrEP delivery. Conclusions PrEP delivery from a CMHC is feasible and acceptable to young women in South Africa. However, to effectively scale-up PrEP it will be necessary to develop diverse PrEP delivery locations and modalities to meet AGYW HIV prevention needs.

scholarly journals Opportunities for technology-based HIV prevention programming among high school students in Cape Town, South Africa

AIDS Care ◽  
2014 ◽  
Vol 26 (12) ◽  
pp. 1562-1567 ◽  
Author(s):  
Michele L. Ybarra ◽  
Kelvin Mwaba ◽  
Tonya L. Prescott ◽  
Nicolette V. Roman ◽  
Bronwyn Rooi ◽  
...  
Keyword(s):  
South Africa ◽  
High School ◽  
High School Students ◽  
Hiv Prevention ◽  
Cape Town ◽  
School Students ◽  
Prevention Programming
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