Low-Field Magnetic Resonance Imaging Findings in Children with Seizures in Ibadan, Nigeria

2020 ◽  
Vol 6 (4) ◽  
pp. 391-401
Author(s):  
JA Akinmoladun ◽  
GI Ogbole ◽  
ID Famosaya ◽  
RU Joel

Background: Seizure is the most common neurological disorder in children and an important cause of paediatric hospital admission with the highest prevalence in the under-five age group. Magnetic Resonance Imaging (MRI) is the neuro-imaging technique of choice in the initial evaluation of children with epilepsy. High-field MRI is the ideal imaging modality for evaluating seizures but this is not readily available in developing countries. Objective: To analyse the spectrum of MRI findings in children presenting with seizures using a low-field (0.36T) MRI. Methods: Children aged ≤18years with seizures, with cranial MRI at the University College Hospital (UCH), Nigeria between January 2013 and June 2015 were retrospectively reviewed. Results: There were a total of 134 patients with 53% as adolescents and most of them (85; 63.4%) had abnormal cranial MRI findings. More male children had abnormal findings (52; 61.2%) and most abnormal findings (42; 49.4%) were reported among adolescents. The most frequent abnormality was hydrocephalus (23.5%) from various causes followed by cerebral tumours (14.1%) and ischaemic cerebral infarcts (11.8%). In the adolescents, intracranial tumours (21.4%) were the most frequent abnormal findings, while hydrocephalus was commoner in children aged less than 10 years, accounting for 33.3% and 36.0% among the 1-5 years and 6-11 years age groups respectively. Conclusion: Low-field MRI, which is more readily available, can provide substantial preliminary findings to aid the management of children with epilepsies. Improved access to high-field MRI through cost reduction and early MR imaging evaluation in the course of illness are desirable.

2017 ◽  
Vol 30 (02) ◽  
pp. 143-152 ◽  
Author(s):  
Charles Ley ◽  
Kerstin Hansson ◽  
Lennart Sjöström ◽  
Martin Rapp

SummaryObjectives: To describe postoperative computed tomography (CT) and magnetic resonance imaging (MRI) findings in dogs with degenerative lumbosacral stenosis (DLSS) treated by dorsal laminectomy and partial discectomy.Methods: Prospective clinical case study of dogs diagnosed with and treated for DLSS. Surgical and clinical findings were described. Computed tomography and low field MRI findings pre- and postoperatively were described and graded. Clinical, CT and MRI examinations were performed four to 18 months after surgery.Results: Eleven of 13 dogs were clinically improved and two dogs had unchanged clinical status postoperatively despite imaging signs of neural compression. Vacuum phenomenon, spondylosis, sclerosis of the seventh lumbar (L7) and first sacral (S1) vertebrae endplates and lumbosacral intervertebral joint osteoarthritis became more frequent in postoperative CT images. Postoperative MRI showed mild disc extrusions in five cases, and in all cases contrast enhancing non-discal tissue was present. All cases showed contrast enhancement of the L7 spinal nerves both pre- and postoperatively and seven had contrast enhancement of the lumbosacral intervertebral joints and paraspinal tissue postoperatively. Articular process fractures or fissures were noted in four dogs.Clinical significance: The study indicates that imaging signs of neural compression are common after DLSS surgery, even in dogs that have clinical improvement. Contrast enhancement of spinal nerves and soft tissues around the region of disc herniation is common both pre- and postoperatively and thus are unreliable criteria for identifying complications of the DLSS surgery.Supplementary Material to this article is available online at https://doi.org/10.3415/VCOT-16-06-0096


2020 ◽  
Vol 27 (3) ◽  
pp. 352-361 ◽  
Author(s):  
Silvanose Biju ◽  
Tatjana N. Parac-Vogt

Paramagnetic Lanthanide ions incorporated into nano- architectures are emerging as a versatile platform for Magnetic Resonance Imaging (MRI) contrast agents due to their strong contrast enhancement effects combined with the platform capability to include multiple imaging modalities. This short review examines the application of lanthanide based nanoarchitectures (nanoparticles and nano- assemblies) in the development of multifunctional probes for single and multimodal imaging involving high field MRI as one imaging modality.


2018 ◽  
Vol 6 (1) ◽  
pp. 62-65
Author(s):  
Bipan Shrestha ◽  
Kishor Man Shrestha ◽  
Alok Pandey

Introduction: Pyogenic sacroiliitis accounts for 12% of all cases of septic arthritis with less than 200 cases reported in the English literature since the beginning of the twentieth century. Considerable delay between presentation and diagnosis is seen because of unusual presentation and diagnostic dilemma. Cultures of joint fluid usually grow Staphylococcus aureus. Magnetic resonance imaging has been found to be the most useful imaging modality in diagnosis. Being very uncommon disease in children, the key to successful management is early diagnosis in which computed tomography (CT), bone scans, and magnetic resonance imaging (MRI) findings play a crucial role. If the diagnosis is established promptly, most patients can be managed successfully with antimicrobial therapy with excellent prognosis. Most reported cases required prolonged antimicrobial therapy of six to nine weeks. Presented here is a child with pyogenic sacroiliitis managed at our hospital (Universal College of Medical Sciences Teaching Hospital-UCMSTH) and review of the literature on this relatively rare diagnosis. Journal of Universal College of Medical SciencesVol. 6, No. 1, 2018, Page: 62-65


RSC Advances ◽  
2017 ◽  
Vol 7 (61) ◽  
pp. 38125-38134 ◽  
Author(s):  
Abhinandan Banerjee ◽  
Barbara Blasiak ◽  
Eva Pasquier ◽  
Boguslaw Tomanek ◽  
Simon Trudel

PEGylated MFe2O4(M = Mn through Zn) spinel ferrite preparedviaa novel one-pot synthesis were evaluated for high-field (B0= 9.4 T) magnetic resonance imaging.


2015 ◽  
Vol 43 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Marie Feletar ◽  
Stephen Hall ◽  
Paul Bird

Objective.To assess the responsiveness of high- and low-field extremity magnetic resonance imaging (MRI) variables at multiple timepoints in the first 12 weeks post-antitumor necrosis factor (anti-TNF) therapy initiation in patients with psoriatic arthritis (PsA) and active dactylitis.Methods.Twelve patients with active PsA and clinical evidence of dactylitis involving at least 1 digit were recruited. Patients underwent sequential high-field conventional (1.5 Tesla) and extremity low-field MRI (0.2 Tesla) of the affected hand or foot, pre- and postgadolinium at baseline (pre-TNF), 2 weeks (post-TNF), 6 weeks, and 12 weeks. A blinded observer scored all images on 2 occasions using the PsA MRI scoring system.Results.Eleven patients completed the study, but only 6 patients completed all high-field and low-field MRI assessments. MRI scores demonstrated rapid response to TNF inhibition with score reduction in tenosynovitis, synovitis, and osteitis at 2 weeks. Intraobserver reliability was good to excellent for all variables. High-field MRI demonstrated greater sensitivity to tenosynovitis, synovitis, and osteitis and greater responsiveness to change posttreatment. Treatment responses were maintained to 12 weeks.Conclusion.This study demonstrates the use of MRI in detecting early response to biologic therapy. MRI variables of tenosynovitis, synovitis, and osteitis demonstrated responsiveness posttherapy with high-field scores more responsive to change than low-field scores.


2009 ◽  
Vol 23 (9) ◽  
pp. 639-641 ◽  
Author(s):  
Michelle Buresi ◽  
Iman Zandieh ◽  
Alexander G Nagy ◽  
Audrey Spielmann ◽  
William C Yee ◽  
...  

A case of a 60-year-old man with recurrent rectal villous adenoma is described. Preoperative staging with endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI) revealed very discordant results. EUS showed a tumour present in the mucosa with no submucosal invasion, while MRI revealed invasion of the muscularis propria consistent with an invasive stage T2 carcinoma. Based on the MRI findings, the patient underwent a low anterior resection of the tumour. The surgical pathology specimen revealed a villous adenoma with low-grade dysplasia but no carcinoma and no extension into the muscularis propria. The present case highlights the uncertainty that currently exists as to which imaging modality provides the greatest accuracy in the staging of rectal cancer and in guiding the type of surgical procedure performed. Two recent meta-analyses and a systematic review of the literature point to EUS as the imaging modality of choice for determining muscularis propria and perirectal tissue invasion, as well as nodal involvement.


Sign in / Sign up

Export Citation Format

Share Document