Long-term effects of the Meniett device in Japanese patients with Meniere's disease and delayed endolymphatic hydrops reported by the Middle Ear Pressure Treatment Research Group of Japan

Objective: To evaluate the therapeutic effects of middle ear tendon resection (METR) on middle ear myoclonic tinnitus (MEMT) and to investigate its long-term effects on hearing and hyperacusis. Materials and Methods: Thirty-seven patients with MEMT with a mean age of 33.2 ± 11.8 years were included in this study. METR was performed on all 37 MEMT patients (41 ears) between November 2004 and August 2016. The mean follow-up period was 16.1 months. We examined changes in tinnitus and accompanying stress and depression in patients after surgery, and examined the hearing changes and the occurrence of complications including hyperacusis. Results: After surgery, 34 (91.9%) patients exhibited complete resolution of MEMT during their follow-up period, and 3 patients showed a partial response. The mean Visual Analog Scale (VAS) scores for tinnitus severity, the Tinnitus Handicap Inventory (THI), and stress index decreased significantly after surgery (p < 0.05, paired t test). No patient developed hearing loss or hyperacusis following surgery. Preexisting hyperacusis even improved in most of the patients with intractable MEMT after surgery. Recurrence of the symptom occurred in only 1 patient, who underwent revision surgery with improvement. We observed 1 case of postoperative delayed facial palsy with complete recovery in 2 weeks. Conclusions: METR seems to be an effective and safe treatment option for intractable MEMT, considering its high control rate of tinnitus and no long-term harmful effects on hearing and hyperacusis.

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Long-term effects on plasma lipids of diet and drugs to treat hypertension. Treatment of Mild Hypertension Study (TOMHS) Research Group

JAMA ◽

10.1001/jama.275.20.1549 ◽

1996 ◽

Vol 275 (20) ◽

pp. 1549-1556 ◽

Cited By ~ 20

Author(s):

R. H. Grimm

Keyword(s):

Research Group ◽

Plasma Lipids ◽

Mild Hypertension ◽

Hypertension Treatment ◽

Long Term Effects

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Speech Therapy for Children Who Stutter

Advances in Psychology, Mental Health, and Behavioral Studies - Handbook of Research on Psychosocial Perspectives of Human Communication Disorders ◽

10.4018/978-1-5225-4955-0.ch017 ◽

2018 ◽

pp. 321-344

Author(s):

Divya Seth ◽

Santosh Maruthy

Keyword(s):

Behavioral Intervention ◽

Speech Therapy ◽

Rating Scales ◽

Evidence Base ◽

Long Term Effects ◽

Popular Approach ◽

Severity Rating ◽

Treatment Research ◽

Age Range

This chapter aims to investigate and evaluate the evidence available for stuttering treatment research in children who stutter (CWS) and provide a qualitative review of the same. Studies were considered for review if (1) they were behavioral intervention of stuttering for children, (2) participants were in the age range of 2-18 years, and (3) the outcomes reported assessed stuttering. Twenty-seven studies were obtained through an electronic search of databases covering two approaches and 10 techniques. The analysis of these studies revealed that direct approaches have a stronger evidence base in comparison to the indirect approaches. The most popular approach with maximum studies is the early intervention Lidcombe program. The commonly used outcome measures included the percentage of syllables stuttered, syllables per minute, and severity rating scales. The conclusion drawn from the review suggest that evidence base to support behavioral intervention of CWS exists for a limited number of intervention techniques and among them very few exploring the long-term effects of the intervention.

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Long-Term Effects of Pioglitazone on Carotid Atherosclerosis in Japanese Patients with Type 2 Diabetes without a Recent History of Macrovascular Morbidity

Journal of Atherosclerosis and Thrombosis ◽

10.5551/jat.4663 ◽

2010 ◽

Vol 17 (11) ◽

pp. 1132-1140 ◽

Cited By ~ 24

Author(s):

Yoshimitsu Yamasaki ◽

Naoto Katakami ◽

Shigetaka Furukado ◽

Kazuo Kitagawa ◽

Kazuyuki Nagatsuka ◽

...

Keyword(s):

Type 2 Diabetes ◽

Carotid Atherosclerosis ◽

Japanese Patients ◽

Recent History ◽

Long Term Effects ◽

History Of

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Long-Term Effects of Silastic?? Sheeting in the Middle Ear

The Laryngoscope ◽

10.1288/00005537-199210000-00002 ◽

1992 ◽

Vol 102 (10) ◽

pp. 1097-1102 ◽

Cited By ~ 26

Author(s):

Matthew Ng ◽

Fred H. Linthicum

Keyword(s):

Middle Ear ◽

Long Term Effects

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Long-term effects of continuous positive airway pressure treatment on subclinical atherosclerosis in obstructive sleep apnoea syndrome

Medicina Clínica (English Edition) ◽

10.1016/j.medcle.2016.03.028 ◽

2016 ◽

Vol 147 (1) ◽

pp. 1-6

Author(s):

Raquel Català ◽

Raimon Ferré ◽

Anna Cabré ◽

Josefa Girona ◽

María Porto ◽

...

Keyword(s):

Continuous Positive Airway Pressure ◽

Airway Pressure ◽

Positive Airway Pressure ◽

Subclinical Atherosclerosis ◽

Sleep Apnoea ◽

Obstructive Sleep Apnoea Syndrome ◽

Pressure Treatment ◽

Long Term Effects ◽

Obstructive Sleep

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Pneumococcal Otitis Media following Middle Ear Deflation

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348948109000119 ◽

1981 ◽

Vol 90 (1) ◽

pp. 72-76 ◽

Cited By ~ 13

Author(s):

William L. Meyerhoff ◽

G. Scott Giebink ◽

Donald Shea

Keyword(s):

Otitis Media ◽

Middle Ear ◽

Endolymphatic Hydrops ◽

Acute Otitis Media ◽

Scala Tympani ◽

Nasopharyngeal Colonization ◽

Normal Morphology ◽

Time Period ◽

Middle Ear Pressure ◽

Histologic Changes

Temporal bone histology has been studied in chinchillas following middle ear deflation in the presence of nasopharyngeal colonization with S pneumoniae. All animals sacrificed within one hour following deflation had similar middle ear hsitology regardless of whether or not the animals had been colonized with S pneumoniae. All animals with negative nasopharyngeal culture for S pneumoniae sacrificed from 3–24 days following − 30 mm Hg negative middle ear pressure had negative middle ear cultures and normal morphology. During the same time period, however, nearly 60% of animals colonized with S pneumoniae developed acute otitis media with positive middle ear cultures for S pneumoniae. Histologic changes in the middle ear included the presence of effusion, leukocytes, granulation tissue, osteoneogenesis, mucosal metaplasia, and hemorrhage. Changes in the inner ear were much less frequent and included some leukocyte infiltration with hyperemia in the scala tympani and endolymphatic hydrops.

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