Urinary Excretion of Iohexol after Enteral Administration in Rats with Radiation Injury of the Small Intestine

1991 ◽  
Vol 26 (10) ◽  
pp. 1097-1106 ◽  
Author(s):  
K. E. Solheim ◽  
F. Lærum ◽  
A. Stordahl ◽  
S. Aase
1992 ◽  
Vol 68 (1) ◽  
pp. 195-207 ◽  
Author(s):  
J. B. Schutte ◽  
J. de Jong ◽  
E. J. van Weerden ◽  
S. Tamminga

The pentose sugar l-arabinose is one of the most abundant components released by complete hydrolysis of non-starch polysaccharides of feed ingredients of vegetable origin. Two studies were conducted to investigate the apparent ileal digestibility and urinary excretion of l-arabinose at dietary inclusion levels of 50 and 100 g/kg, and 25, 50, 75 and 100 g/kg respectively, in pigs. As a reference, d-glucose was included in the studies. Water intake, ileal flow of volatile fatty acids and ileal and faecal digestibilities of dietary nutrients in pigs fed on the different diets were also examined. Castrated pigs were prepared with a post-valvular T-caecum cannula to measure ileal digestibility. Faecal digestibility was measured in non-cannulated pigs. Apparent ileal digestibility of l-arabinose was found to be approximately 70%. The presence of l-arabinose in the diet increased ileal flow of volatile fatty acids and lactic acid, suggesting the occurrence of microbial degradation of l-arabinose in the pig small intestine. l-arabinose was partly excreted in the urine. The extent of this urinary excretion as a percentage of intake increased linearly (P < 0.01) as the dietary level increased. In pigs fed on the 25 g l-arabinose/kg diet, 10.9% of the l-arabinose consumed appeared in the urine. This level was increased to 14.7% when pigs were fed on a diet containing 100 g l-arabinose/kg diet. Faecal digestibility and retention of nitrogen decreased significantly in pigs fed on the l-arabinose diets.


1993 ◽  
Vol 69 (2) ◽  
pp. 455-466 ◽  
Author(s):  
E. J. Van Weerden ◽  
J. Huisman

In a study with twelve pigs of 60–70 kg live weight provided with a re-entrant cannula at the end of the ileum, and twelve intact, non-cannulated pigs, the fate of dietary doses of 100 and 200 g isomalt/kg during gastrointestinal passage was examined. From sugar analyses in ileal chyme it was calculated that 0.43 and 0.30 of the isomalt consumed was digested in the small intestine with the 100 and 200 g/kg doses of isomalt respectively. From findings on ileal energy digestibility it was calculated that, because of a secondary effect of isomalt on the digestion of the basal diet, isomalt digestibility in the small intestine was distinctly lower. In faeces no sugars were found, so faecal digestibility of isomalt was 1.00 for both doses. The bacterial fermentation in the large intestine of the isomalt not digested in the small intestine caused an increase in the faecal excretion of nitrogen and energy. This increased faecal excretion was hardly (nitrogen) or not (energy) compensated by a decreased urinary excretion.


1961 ◽  
Vol 200 (4) ◽  
pp. 794-796 ◽  
Author(s):  
Robert M. Donaldson ◽  
Horacio A. Dolcini ◽  
Seymour J. Gray

The urinary excretion of indican and of free and total indoleacetic acid is significantly increased in the rat in the presence of a localized area of intestinal stasis produced surgically by the creation of a pouch in the small intestine. Tryptamine, serotonin and 5-hydroxyindoleacetic acid excretion in the urine is not altered. Evidence that intestinal stasis and bacterial activity within the pouch are responsible for the increased amounts of indican and indoleacetic acid in the urine is supported by the facts that a) indole compounds are not increased in the urine when the intestinal pouch is formed so that peristalsis keeps it empty, b) removal of the intestinal pouch results in a reduction of indican and indoleacetic acid to normal levels within 24 hours and c) oral administration of neomycin promptly reduces the excretion of these compounds to normal levels.


1998 ◽  
Vol 1998 ◽  
pp. 23-23
Author(s):  
F. Herrera Gomez ◽  
F.D.DeB Hovell ◽  
C.A. Sandoval Castro

The purine derivatives (PD) have been proposed as a non-invasive method to estimate microbial-N supply to the small intestine (Chen et al., 1990a; Verbic et al., 1990). The use of PD urinary excretion has the advantage that it can be used with intact animals thus reducing the concern of animal welfare issues. Although, there are known differences in purine metabolism between cattle (B. taurus), sheep and buffaloes (Bubalis bubalis) (Chen et al., 1990b; Chen et al., 1996), no direct comparison of PD urinary excretion has been made so far between cattle especies, therefore, the objective of the present experiment was to compare PD urinary excretion of B. taurus and B. indicus cattle fed similar diets under tropical conditions.


1990 ◽  
Vol 25 ◽  
pp. S115-S116 ◽  
Author(s):  
FRODE LAERUM ◽  
KIRSTI EVERS SOLHEIM ◽  
ARVID STORDAHL ◽  
STEINAR AASE

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