Traumatic brain injury in Spanish-speaking individuals: Research findings and clinical implications

Brain Injury ◽  
2012 ◽  
Vol 26 (6) ◽  
pp. 801-804 ◽  
Author(s):  
Juan Carlos Arango-Lasprilla
Brain Injury ◽  
2012 ◽  
Vol 26 (6) ◽  
pp. 864-874 ◽  
Author(s):  
A. García-Molina ◽  
J.M. Tormos ◽  
M. Bernabeu ◽  
C. Junqué ◽  
T. Roig-Rovira

2014 ◽  
Vol 2014 ◽  
pp. 1-9
Author(s):  
Elaine de Guise ◽  
Joanne LeBlanc ◽  
Jehane Dagher ◽  
Simon Tinawi ◽  
Julie Lamoureux ◽  
...  

Background. The aim of this study was to compare acute outcome between men and women after sustaining a traumatic brain injury (TBI). Methods. A total of 5,642 patients admitted to the Traumatic Brain Injury Program of the McGill University Health Centre-Montreal General Hospital between 2000 and 2011 and diagnosed with a TBI were included in the study. The overall percentage of women with TBI was 30.6% (n= 1728). Outcome measures included the length of stay (LOS), the Extended Glasgow Outcome Scale (GOSE), the functional independence measure instrument (FIM), discharge destination, and mortality rate. Results. LOS, GOSE, the FIM ratings, and discharge destination did not show significant differences between genders once controlling for several confounding variables and running the appropriate diagnostic tests (P<0.05). However, women had less chance of dying during their acute care hospitalization than men of the same age, with the same TBI severity and following the same mechanism of injury. Although gender was a statistically significant predictor, its contribution in explaining variation in mortality was small. Conclusion. More research is needed to better understand gender differences in mortality; as to date, the research findings remain inconclusive.


2004 ◽  
Vol 56 (1-2) ◽  
pp. 113-125 ◽  
Author(s):  
Ruediger Noppens ◽  
Ansgar M. Brambrink

2006 ◽  
Vol 12 (1) ◽  
pp. 100-110 ◽  
Author(s):  
CARLO ZIINO ◽  
JENNIE PONSFORD

Research findings have suggested that individuals with traumatic brain injury (TBI) show greater psychophysiological and subjective costs associated with performing vigilance tasks, but have not examined relationships with fatigue. The present study aimed to investigate vigilance and its relationship with subjective and objective fatigue measures. Forty-six TBI participants and 46 controls completed a 45-minute vigilance task. They also completed a subjective fatigue scale (the VAS-F) and a selective attention task before and after the vigilance task, and had their blood pressure (BP) monitored. TBI participants performed at a lower level on the vigilance task, but performed at a similar level across the duration of the task. Higher subjective fatigue ratings on the VAS-F were associated with more misses on the vigilance task for TBI participants. TBI participants showed greater increases in diastolic BP, and these were associated with greater increases in subjective fatigue ratings on the VAS-F. A subgroup of TBI participants showed a decline in performance on the vigilance task and also showed disproportionate increases in subjective fatigue. Findings provide support for the coping hypothesis, suggesting that TBI individuals expend greater psychophysiological costs in order to maintain stable performance over time, and that these costs are also associated with subjective increases in fatigue. (JINS, 2006,12, 100–110.)


2010 ◽  
Vol 29 (5) ◽  
pp. E1 ◽  
Author(s):  
Stefano Signoretti ◽  
Roberto Vagnozzi ◽  
Barbara Tavazzi ◽  
Giuseppe Lazzarino

Although numerous studies have been carried out to investigate the pathophysiology of mild traumatic brain injury (mTBI), there are still no standard criteria for the diagnosis and treatment of this peculiar condition. The dominant theory that diffuse axonal injury is the main neuropathological process behind mTBI is being revealed as weak at best or inconclusive, given the current literature and the fact that neuronal injury inherent to mTBI improves, with few lasting clinical sequelae in the vast majority of patients. Clinical and experimental evidence suggests that such a course, rather than being due to cell death, is based on temporal neuronal dysfunction, the inevitable consequence of complex biochemical and neurochemical cascade mechanisms directly and immediately triggered by the traumatic insult. This report is an attempt to summarize data from a long series of experiments conducted in the authors' laboratories and published during the past 12 years, together with an extensive analysis of the available literature, focused on understanding the biochemical damage produced by an mTBI. The overall clinical implications, as well as the metabolic nature of the post-mTBI brain vulnerability, are discussed. Finally, the application of proton MR spectroscopy as a possible tool to monitor the full recovery of brain metabolic functions is emphasized.


Sign in / Sign up

Export Citation Format

Share Document