GE-145, a new low-osmolar dimeric radiographic contrast medium

2010 ◽  
Vol 51 (9) ◽  
pp. 1014-1020 ◽  
Author(s):  
Lars-G. Wistrand ◽  
Astri Rogstad ◽  
Gunnar Hagelin ◽  
Line Roed ◽  
Inger Oulie ◽  
...  
2015 ◽  
Vol 56 (6) ◽  
pp. 702-708 ◽  
Author(s):  
Karoline Meurer ◽  
Michael Laniado ◽  
Norbert Hosten ◽  
Bettina Kelsch ◽  
Barry Hogstrom

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Muhamad Idham Mohamed ◽  
Mohd Khairul Amran Mohammad ◽  
Hairil Rashmizal Abdul Razak ◽  
Khairunisak Abdul Razak ◽  
Wan Mazlina Md Saad

Emerging syntheses and findings of new metallic nanoparticles (MNPs) have become an important aspect in various fields including diagnostic imaging. To date, iodine has been utilized as a radiographic contrast medium. However, the raise concern of iodine threats on iodine-intolerance patient has led to search of new contrast media with lower toxic level. In this animal modeling study, 14 nm iron oxide nanoparticles (IONPs) with silane-polyethylene glycol (SiPEG) and perchloric acid have been assessed for toxicity level as compared to conventional iodine. The nanotoxicity of IONPs was evaluated in liver biochemistry, reactive oxygen species production (ROS), lipid peroxidation mechanism, and ultrastructural evaluation using transmission electron microscope (TEM). The hematological analysis and liver function test (LFT) revealed that most of the liver enzymes were significantly higher in iodine-administered group as compared to those in normal and IONPs groupsP<0.05. ROS production assay and lipid peroxidation indicator, malondialdehyde (MDA), also showed significant reductions in comparison with iodine groupP<0.05. TEM evaluation yielded the aberration of nucleus structure of iodine-administered group as compared to those in control and IONPs groups. This study has demonstrated the less toxic properties of IONPs and it may postulate that IONPs are safe to be applied as radiographic contrast medium.


1987 ◽  
Vol 28 (5) ◽  
pp. 601-602
Author(s):  
A. Alanen ◽  
P. Nummi ◽  
M. Kormano ◽  
K. Irjala

Relaxation times Tl of normal and abnormal urine samples were measured with a 0.02 tesla MRI device in a spectrometric mode. Protein containing urine from patients with glomerulonephritis showed a slight shortening of Tl relaxation time. Radiographic contrast medium, pH, osmolality or glucose in diabetes did not significantly change the Tl relaxation time of urine. Urine can be used as a T1 relaxation reference in MR imaging of the pelvis even if the patient has received radiographic contrast medium or has diabetes or proteinuria for any reason.


1991 ◽  
Vol 84 (1) ◽  
pp. 92-94 ◽  
Author(s):  
CONSTANCE A. JENNINGS ◽  
JOHN DEVEIKIS ◽  
NORIO AZUMI ◽  
HENRY YEAGER

1974 ◽  
Vol 41 (6) ◽  
pp. 688-690
Author(s):  
Edward B. Silberstein ◽  
Alan B. Ashare

✓ The authors report examination of 27 brain scintigraphs performed 1 day following cerebral angiography, and 48 performed within 2 weeks. No artifactual areas of uptake were produced in the scintigraphs by the radiographic contrast medium.


2003 ◽  
Vol 44 (3) ◽  
pp. 265-268
Author(s):  
M. Uhl ◽  
J. Kromeier ◽  
L.-B. Zimmerhackl ◽  
K. Darge

Purpose: To compare the diagnostic accuracy of contrast-enhanced voiding urosonography (VUS) and voiding cystourethrography (VCUG) during simultaneous performance of both examinations. Material and Methods: A total of 24 children, 16 girls and 8 boys, with a mean age of 3.5 years referred for reflux examination were recruited for the study. After transurethral bladder catheterization, radiographic contrast medium, followed directly by the US contrast medium, were administered. Fluoroscopic VCUG and VUS were carried out concurrently in the same patient. When 1 kidney was scanned by ultrasound, fluoroscopy was performed on the contralateral side. Results: In 19 of the 47 kidney-ureter-units (KUU) vesicoureteral reflux (VUR) was detected. In 16 units the reflux was detected by both VCUG and VUS. In 3 KUUs the reflux was detected only at VCUG. All 3 cases were grade 1. Taking the VCUG as the reference standard, VUS had 84% sensitivity, 100% specificity, 100% and 90% positive and negative predictive values, respectively. Conclusion: A dependable comparison could be achieved by performing VCUG and VUS at the same time and under the same conditions. It reconfirmed that VUS is reliable in the exclusion or verification of reflux.


1984 ◽  
Vol 25 (4) ◽  
pp. 337-342 ◽  
Author(s):  
D. H. Carr ◽  
A. C. Walker

The rate of conversion in vitro, of prekallikrein to kallikrein has been measured in 74 reactors to contrast medium and 70 controls. The conversion rate is significantly more rapid in reactors than controls. There was no difference in C1-esterase inhibitor and factor XII levels between reactors and controls. This retrospective investigation suggests that prekallikrein/kallikrein conversion rate may form the basis of a test for differentiating between reactors and non-reactors.


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