Drug Burden Index associated with function in community-dwelling older people in Finland: A cross-sectional study

2011 ◽  
Vol 44 (5) ◽  
pp. 458-467 ◽  
Author(s):  
Danijela Gnjidic ◽  
J. Simon Bell ◽  
Sarah N. Hilmer ◽  
Eija Lönnroos ◽  
Raimo Sulkava ◽  
...  
Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1041 ◽  
Author(s):  
Pilar Pérez-Ros ◽  
Rafael Vila-Candel ◽  
Lourdes López-Hernández ◽  
Francisco Miguel Martínez-Arnau

Objective: This study aims to assess the relationship that frailty has with nutritional status and functional risk factors in community-dwelling older adults. Methods: Cross-sectional study in community-dwelling older people, independent for walking and without impaired cognition. Frailty was assessed by Fried criteria. Nutritional status was analyzed by the Mini Nutritional Assessment Short Form (MNA-SF), biochemical markers (albumin, total proteins, cholesterol, lymphocytes, and hemoglobin); and anthropometric parameters (body mass index [BMI], body fat percentage, handgrip, and perimeters). A comprehensive geriatric assessment analyzed other risk factors: functionality, cognition, falls, comorbidity, polypharmacy, physical activity, and quality of life (QoL). Results: We included 564 elderly people with a mean age of 76.05 (standard deviation 3.97) years; 63.1% (n = 356) were women, and 83.9% (n = 473) were prefrail, and frail. The sample presented high functionality and a nutritional status with a predominance of overweight and obesity. Factors associated with frailty (R2 = 0.43) were age over 75 years (odds ratio [OR] 3.31, 95% confidence interval [CI] 1.76, 6.21; p < 0.001), female gender (OR 2.37, 95% CI 1.24, 4.52; p = 0.009), anemia (OR 2.45, 95% CI 1.19, 5.02; p = 0.015), falls (OR 1.94, 95% CI 1.12, 3.25; p = 0.016) and the fear of falling (OR 4.01: 95% CI 1.76, 9.16; p = 0.001). Performing more than 3 weekly hours of physical activity was found to be a protective factor (OR 0.23, 95% CI 0.15, 0.35; p < 0.001). Conclusions: The relationship between frailty and malnutrition in functionally independent community-dwelling older people is unclear. More studies are needed to know what nutritional markers are related to frailty, cognition, and functionality in order to discriminate the risk factors for community-dwelling older people at risk of malnutrition and dependency.


2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Jeanette Eckerblad ◽  
Kersti Theander ◽  
Anne Ekdahl ◽  
Mitra Unosson ◽  
Ann-Britt Wirehn ◽  
...  

Vaccine ◽  
2020 ◽  
Vol 38 (21) ◽  
pp. 3752-3758
Author(s):  
Ikkoh Yasuda ◽  
Motoi Suzuki ◽  
Bhim Gopal Dhoubhadel ◽  
Mayumi Terada ◽  
Akira Satoh ◽  
...  

2020 ◽  
Vol 138 (6) ◽  
pp. 465-474
Author(s):  
Marcos Kaic Lopes Alves ◽  
Nayara Gomes Nunes Oliveira ◽  
Maycon Sousa Pegorari ◽  
Darlene Mara dos Santos Tavares ◽  
Maria Cristina Soares Rodrigues ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. e014485 ◽  
Author(s):  
Yves Henchoz ◽  
Christophe Büla ◽  
Idris Guessous ◽  
Nicolas Rodondi ◽  
René Goy ◽  
...  

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