A Polymer-Triton X-100 Conjugate Capable of PH-Dependent Red Blood Cell Lysis: A Model System Illustrating the Possibility of Drug Delivery Within Acidic Intracellular Compartments

1994 ◽  
Vol 2 (4) ◽  
pp. 341-347 ◽  
Author(s):  
Ruth Duncan ◽  
Paolo Ferruti ◽  
Dionyssios Sgouras ◽  
Anthony Tuboku-Metzger ◽  
Elisabetta Ranucci ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Lysis ◽  
Model System ◽  
Intracellular Compartments ◽  
Ph Dependent ◽  
Triton X

Haemoglobin-Triton X-100 conjugate as model system for red blood cell lysis

2010 ◽  
Author(s):  
Simona-Florentina Pop ◽  
Rodica-Mariana Ion ◽  
Sanda Doncea
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Lysis ◽  
Model System ◽  
Triton X

Silencing Red Blood Cell Recognition toward Anti-A Antibody by Means of Polyelectrolyte Layer-by-Layer Assembly in a Two-Dimensional Model System†

Langmuir ◽  
2009 ◽  
Vol 25 (24) ◽  
pp. 14071-14078 ◽  
Author(s):  
Sania Mansouri ◽  
Julien Fatisson ◽  
Zhimei Miao ◽  
Yahye Merhi ◽  
Françoise M. Winnik ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Model System ◽  
Layer By Layer ◽  
Cell Recognition ◽  
Two Dimensional ◽  
Dimensional Model ◽  
Polyelectrolyte Layer ◽  
Two Dimensional Model ◽  
Layer Assembly

Does the storage time of human blood have any impact on the outcome of the red blood cell lysis cytotoxicity test?

2006 ◽  
Vol 164 ◽  
pp. S113
Author(s):  
Jens Lichtenberg ◽  
Inge Birgit Jørgensen ◽  
Ninna Willestofte Berg
Keyword(s):  
Blood Cell ◽  
Human Blood ◽  
Red Blood Cell ◽  
Storage Time ◽  
Cell Lysis ◽  
Cytotoxicity Test

scholarly journals Adaptation of red blood cell lysis represents a fundamental breakthrough that improves the sensitivity of S almonella detection in blood

2015 ◽  
Vol 118 (5) ◽  
pp. 1199-1209 ◽  
Author(s):  
M.A. Boyd ◽  
S.M. Tennant ◽  
J.H. Melendez ◽  
D. Toema ◽  
J.E. Galen ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Lysis

Effect of Triton X-100 on Electrophoretic Mobility of Red Blood Cell Ghosts from Normal Individuals and Patients With Tay—Sachs Disease

1971 ◽  
Vol 17 (4) ◽  
pp. 332-334 ◽  
Author(s):  
M Pourfar ◽  
S Levy
Keyword(s):  
Sialic Acid ◽  
Blood Cell ◽  
Cellulose Acetate ◽  
Electrophoretic Mobility ◽  
Red Blood Cell ◽  
Moving Boundary ◽  
Sialic Acid Content ◽  
Tay Sachs Disease ◽  
Nonionic Detergent ◽  
Triton X

Abstract The negative surface charge of red blood cell ghosts and their anodal electrophoretic migration are largely due to their sialic acid moiety. The RBC of patients with Tay—Sachs disease are thought to contain increased amounts of sialic acid. Electrophoretic mobility and ganglioside content of RBC ghosts were compared in four patients with Tay—Sachs disease and eight normal controls. There was no measurable difference in electrophoretic mobility on cellulose acetate or acrylamide gel. The sialic acid content of lyophilized RBC ghosts was about the same for samples from both patients and controls. The nonionic detergent, Triton X-100, interacts with the ghost glycolipoprotein, causing a reversal of migration, both on cellulose acetate and moving-boundary electrophoresis. Acrylamide gel, by its sieving effect, disrupts the complex, which then migrates anodally again.

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