scholarly journals Sex differences in ADHD trajectories across childhood and adolescence

Author(s):  
Aja Louise Murray ◽  
Tom Booth ◽  
Manuel Eisner ◽  
Bonnie Auyeung ◽  
George Murray ◽  
...  

Background: Previous studies have hinted at sex differences in developmental trajectories in ADHD symptoms; however, little is known about the nature or cause of these differences and their implications for clinical practice.Method: We used growth mixture modelling in a community-ascertained cohort of n=1571 participants to study sex differences in ADHD symptom developmental trajectories across the elementary and secondary school years. Participants were measured at ages 7, 8, 9, 10, 11, 12, 13, and 15.Results: We found that females were more likely to show large symptom increases in early adolescence while males were more likely to show elevated symptoms from childhood. For both males and females, early adolescence represented a period of vulnerability characterised by relatively sudden symptom increases. Conclusions: Females affected by hyperactivity/impulsivity may be more likely to be excluded from diagnosis due to current age of onset criteria. More attention should be paid to early adolescence as a period of risk for hyperactivity/impulsivity symptom onset or worsening.

2010 ◽  
Vol 41 (1) ◽  
pp. 47-58 ◽  
Author(s):  
C. J. Mackie ◽  
N. Castellanos-Ryan ◽  
P. J. Conrod

BackgroundResearch suggests that psychotic-like experiences (PLEs) in the general population are common, but can reflect either transitory or persistent developmental phenomena. Using a general adolescent population it was examined whether different developmental subtypes of PLEs exist and whether different trajectories of PLEs are associated with certain environmental risk factors, such as victimization and substance use.MethodSelf-reported PLEs were collected from 409 adolescents (mean age 14 years 7 months) at four time points, each 6 months apart. General growth mixture modelling was utilized to identify classes of adolescents who followed distinct trajectories of PLEs across this period. Predictors of class membership included demographics, personality, victimization, depression, anxiety and substance use.ResultsWe identified the following three developmental subgroups of PLEs: (1) persistent; (2) increasing; (3) low. Adolescents on the persistent trajectory reported frequent victimization and consistent elevated scores in depression and anxiety. Adolescents on the increasing trajectory were engaging in cigarette use prior to any increases in PLEs and were engaging in cocaine, cannabis and other drug use as PLEs increased at later time points.ConclusionsThe findings suggest that different developmental subgroups of PLEs exist in adolescence and are differentially related to victimization and substance use.


2016 ◽  
Vol 29 (3) ◽  
pp. 919-928 ◽  
Author(s):  
Michel G. Nivard ◽  
Gitta H. Lubke ◽  
Conor V. Dolan ◽  
David M. Evans ◽  
Beate St. Pourcain ◽  
...  

AbstractThis study sought to identify trajectories of DSM-IV based internalizing (INT) and externalizing (EXT) problem scores across childhood and adolescence and to provide insight into the comorbidity by modeling the co-occurrence of INT and EXT trajectories. INT and EXT were measured repeatedly between age 7 and age 15 years in over 7,000 children and analyzed using growth mixture models. Five trajectories were identified for both INT and EXT, including very low, low, decreasing, and increasing trajectories. In addition, an adolescent onset trajectory was identified for INT and a stable high trajectory was identified for EXT. Multinomial regression showed that similar EXT and INT trajectories were associated. However, the adolescent onset INT trajectory was independent of high EXT trajectories, and persisting EXT was mainly associated with decreasing INT. Sex and early life environmental risk factors predicted EXT and, to a lesser extent, INT trajectories. The association between trajectories indicates the need to consider comorbidity when a child presents with INT or EXT disorders, particularly when symptoms start early. This is less necessary when INT symptoms start at adolescence. Future studies should investigate the etiology of co-occurring INT and EXT and the specific treatment needs of these severely affected children.


2021 ◽  
Author(s):  
Jasmine Raw ◽  
Polly Waite ◽  
Samantha Pearcey ◽  
Cathy Creswell ◽  
Adrienne Shum ◽  
...  

Background The COVID-19 pandemic has significantly changed the lives of children and adolescents, forcing them into periods of prolonged social isolation and time away from school. Understanding the psychological consequences of the UK’s lockdown for children and adolescents, the associated risk factors, and how trajectories may vary for children and adolescents in different circumstances is essential so that the most vulnerable children and adolescents can be identified and appropriate support can be implemented. Methods Parents and carers (n = 2988) in the U.K. with children and adolescents aged between 4 and 16 years completed an online survey about their child’s mental health. Growth curve analysis was used to examine the changes in conduct problems, hyperactivity/inattention and emotional symptoms between the end of March/beginning of April and July using data from four monthly assessments. Additionally, growth mixture modelling identified mental health trajectories for conduct problems, hyperactivity/inattention and emotional symptoms separately and subsequent regression models were used to estimate predictors of mental health trajectory membership. Results Overall levels of hyperactivity and conduct problems increased over time whereas emotional symptoms remained relatively stable, though declined somewhat between June and July. Change over time varied according to child age, the presence of siblings, and with Special Educational Needs (SEN)/ Neurodevelopmental Disorders (ND). Subsequent growth mixture modelling identified three, four and five trajectories for hyperactivity/inattention, conduct problems and emotional symptoms, respectively. Though many children maintained “stable3low” symptoms, others experienced elevated symptoms by July. These children were more likely to have a parent/carer with higher levels of psychological distress, to have SEN/ND, or to be younger in age. Conclusions The findings support previous literature and highlight that certain risk factors were associated with poorer mental health trajectories for children and adolescents during the pandemic.


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