Chapter 2 sets the compass through a work that seems to have little to say about sampling. 4’33” (four thirty-three) by John Cage is based on no (performed) sounds, no flashy pyrotechnics in its execution, nor reverence for the notion of music as a singular, individual creative act, or performance. The chapter considers Cage’s evocation of “silence” as the sampled material that is at stake in this iconic piece. I consider how silence, and silencing work in the context of censorship and social control given that the timeframe for the inception of 4’33” resonates with post-World War II, mid-twentieth-century United States during the Cold War. Engaging with this work can also tell us something about the role of censorship in public arts life half a century later, in the US shortly after the Al Qaeda attacks on September 11, 2001. As I argue, when regarded as a material of music, and thereby as a source from which to “sample” silence, 4’33”offers both a sonic and “sound-less” baseline for the four case studies to follow. “Silence” as rendered in Cage’s work, its wider connotations and evocation of the sensation of sound-filled stillness also serve as a signal for instances of domination, of how oppression can take place quietly, without fanfare. Considering silence as a geocultural, socio-musicological matter allows us a moment to retune our ears and minds by encountering the broader (in)audible domains through, and from which sampling practices take place.