scholarly journals Uterine Perforation with Omental Prolapse in a Case of Unsafe Abortion

2012 ◽  
Vol 2 (3) ◽  
pp. 145-147 ◽  
Author(s):  
Parinitha S Sangam ◽  
Nirmala M Jayakumar ◽  
Laxmi V Yaliwal
Keyword(s):  
Inflammatory Cell ◽  
Past History ◽  
Termination Of Pregnancy ◽  
Inflammatory Cell Infiltrate ◽  
Emergency Laparotomy ◽  
Uterine Perforation ◽  
Medical Sciences ◽  
Medical Termination ◽  
Physician Patient ◽  
Omental Fat

We report a rare case of prolapsed omentum presenting as mass per vagina in a 24 year old unmarried female following dilatation and curettage for termination of pregnancy by unqualified physician. Patient presented to Obstetrics and gynaecology (OBG) outpatient with bleeding per vagina since 15 days. Per speculum examination showed a greyish yellow mass protruding through cervical os into the vagina. Ultrasonography showed defect in the fundus of uterus. Past history revealed, she had undergone medical termination of pregnancy (MTP) outside at 5th month of gestation by nonallopathic doctor. Emergency laparotomy was done. Histopathologic examination of mass showed omental fat arranged in lobules with mixed inflammatory cell infiltrate. Uterine perforation is a well known complication of induced abortion. Although most uterine perforations at the time of curettage during abortion go unrecognized, serious complications do occur. DOI: http://dx.doi.org/10.3126/ajms.v2i3.4264 Asian Journal of Medical Sciences 2 (2011) 145-147   

Diabetes and Vascular Disease: Is It All About Glycemia?

2019 ◽  
Vol 25 (29) ◽  
pp. 3112-3127 ◽  
Author(s):  
Alessandra Vecchié ◽  
Fabrizio Montecucco ◽  
Federico Carbone ◽  
Franco Dallegri ◽  
Aldo Bonaventura
Keyword(s):  
Vascular Disease ◽  
Inflammatory Cell ◽  
Vascular Dysfunction ◽  
Microvascular Complications ◽  
Coagulation Cascade ◽  
Inflammatory Cell Infiltrate ◽  
Extracellular Traps ◽  
Thrombotic Complications ◽  
Independent Entity ◽  
Complications And Mortality

Background: Diabetes is increasing over time, mainly driven by obesity, aging, and urbanization. Classical macro- and microvascular complications represent the final result of a complex interplay involving atherosclerosis at all stages. Methods: In this review, we aim at focusing on current updates in the pathophysiology of vascular disease in diabetes and discussing how new therapies might influence the management of these patients at high cardiovascular risk. Diabetes shows accelerated atherosclerosis with a larger inflammatory cell infiltrate, thus favoring the development of heart failure. ‘Diabetic cardiomyopathy’ perfectly describes a specific ischemia- and hypertension- independent entity due to diabetes-related metabolic alterations on myocardial function. Moreover, platelets from subjects with diabetes display a typical hyperreactivity explaining the stronger adhesion, activation, and aggregation. Additionally, diabetes provokes an exaggerated stimulation of the endothelium, with an increased release of reactive oxygen species and a reduced release of nitric oxide, both key elements of the endothelial dysfunction. Also, the coagulation cascade and leukocytes activate contributing to this pro-thrombotic environment. Neutrophils have been recently recognized to play a pivotal role by releasing neutrophil extracellular traps. Finally, microparticles from platelets, neutrophils or monocytes are detrimental effectors on the vessel wall and are involved both in vascular dysfunction and in thrombotic complications. Conclusion: In light of these findings, the therapeutic management of diabetes needs to be mostly focused on limiting the progression of complications by targeting precise pathophysiological mechanisms rather than the mere glycemic control, which failed to markedly reduce the risk for macrovascular complications and mortality.

scholarly journals Higher Number of EBI3 Cells in Mucosal Chronic Hyperplastic Candidiasis May Serve to Regulate IL-17-Producing Cells

2021 ◽  
Vol 7 (7) ◽  
pp. 533
Author(s):  
Ailish Williams ◽  
Helen Rogers ◽  
David Williams ◽  
Xiao-Qing Wei ◽  
Damian Farnell ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Oral Lichen Planus ◽  
Inflammatory Cell ◽  
Candida Infection ◽  
Inflammatory Cell Infiltrate ◽  
T Helper ◽  
Cell Infiltrate ◽  
High Prevalence ◽  
Squamous Cell Papilloma ◽  
Oral Lichen

Previous research into the inflammatory cell infiltrate of chronic hyperplastic candidosis (CHC) determined that the immune response is primarily composed of T cells, the majority of which are T helper (CD4+) cells. This present investigation used immunohistochemistry to further delineate the inflammatory cell infiltrate in CHC. Cells profiled were those expressing IL-17A cytokine, EBI3 and IL-12A subunits of the IL-35 cytokine, and FoxP3+ cells. Squamous cell papilloma (with Candida infection) and oral lichen planus tissues served as comparative controls to understand the local immune responses to Candida infection. The results demonstrated that Candida-induced inflammation and immune regulation co-exist in the oral mucosa of CHC and that high prevalence of cells expressing the EBI3 cytokine subunit may play an important role in this regulation. This balance between inflammation and immune tolerance toward invading Candida in the oral mucosa may be critical in determining progress of infection.

Clinical outcomes from a prospective study evaluating the role of ambulation during medical termination of pregnancy

Contraception ◽  
2012 ◽  
Vol 85 (4) ◽  
pp. 398-401 ◽  
Author(s):  
Kamal Ojha ◽  
David J. Gillott ◽  
Patricia Wood ◽  
Elizabeth Valcarcel ◽  
Arti Matah ◽  
...  
Keyword(s):  
Prospective Study ◽  
Clinical Outcomes ◽  
Termination Of Pregnancy ◽  
Medical Termination Of Pregnancy ◽  
Medical Termination ◽  
A Prospective Study

Medical Termination of Pregnancy

2000 ◽  
Vol 342 (13) ◽  
pp. 946-956 ◽  
Author(s):  
Sophie Christin-Maitre ◽  
Philippe Bouchard ◽  
Irving M. Spitz
Keyword(s):  
Termination Of Pregnancy ◽  
Medical Termination Of Pregnancy ◽  
Medical Termination

MEDICAL FALLIBILITY

PEDIATRICS ◽  
1977 ◽  
Vol 60 (2) ◽  
pp. 243-243
Author(s):  
Gorovitz ◽  
MacIntyre ◽  
Keyword(s):  
Medical Error ◽  
Medical Profession ◽  
Medical Science ◽  
Medical Problem ◽  
Medical Sciences ◽  
Physician Patient Relationship ◽  
The Public ◽  
Iatrogenic Illness ◽  
The Individual ◽  
Physician Patient

At present, the typical patient is systematically encouraged to believe that his physician will not make a mistake, even though what the physician does may not achieve the desired medical objectives, and even though it cannot be denied that some physicians do make mistakes. The encouragement of this inflated belief in the competence of the physician is of course reinforced by the practice of not keeping systematic and accessible records of medical error. Yet everyone knows that this is a false confidence . . . the current high incidence of iatrogenic illness constitutes a medical problem of enormous proportions, well recognized within government agencies and segments of the medical profession, but only dimly suspected by the public at large. There is still a relatively high probability of a patient suffering from medical error. What patients and the public have to learn is to recognize, accept, and respond reasonably to the necessary fallibility of the individual physician. The physician-patient relationship has to be redefined as one in which necessarily mistakes will be made, sometimes culpably, sometimes because of the state of development of the particular medical sciences at issue, and sometimes, inevitably, because of the inherent limitations in the predictive powers of an enterprise that is concerned essentially with the flourishing of particulars, of individuals. The patient and the public therefore must also understand that medical science is committed to the patient's prospering and flourishing, and that the treatment of the patient is itself a part of that science and not a mere application of it.

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