scholarly journals Different Types of Breast Lump in Relation to Different Age Groups

2014 ◽  
Vol 8 (2) ◽  
pp. 56-58
Author(s):  
ABM Zafar Sadik ◽  
Md Mahmudul Hasan ◽  
Nur-E-Zannat Afroza Haque ◽  
Farid Uddin Ahmed ◽  
Md Zahidul Kabir
Keyword(s):  
Breast Carcinoma ◽  
Age Groups ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lump ◽  
College Hospital ◽  
Medical College ◽  
Group A ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

This prospective observational study was carried out in the inpatient and outpatient department of surgery at Shaheed Ziaur Rahman Medical College Hospital, Bogra, during the period of 01.07.2008 to 31.12.2008 with a view to find out the incidence of breast carcinoma, fibroadenoma or other pathology in different age group. A total 130 patients with palpable breast lump were included in the study. Age of the patients was between 11 to 70 years. In most of the patients with breast lump Fine Needle Aspiration Cytology and biopsy were done. Sometimes ultrasonography, mammography and other routine investigations were also done. Among the study population 53.85% had benign lesions, Breast carcinoma accounted for 46.15% cases, fibroadenoma for 40.76% and fibroadenosis were in 10% cases. Fibroadenoma was common in second and third decade, while carcinoma of breast was common in third and fourth decade in this study. Here we attempted to find out the age incidence of breast lump and its correlation with clinical features, FNAC findings and histopathological report to improve the accuracy of diagnosis and management of breast disease. DOI: http://dx.doi.org/10.3329/fmcj.v8i2.20369 Faridpur Med. Coll. J. 2013;8(2): 56-58

scholarly journals Correlation between Robinson’s cytological grading with Modiied Bloom-Richardson histopathological grading for breast carcinoma

2015 ◽  
Vol 5 (10) ◽  
pp. 791-797
Author(s):  
S Chalise ◽  
A Jha ◽  
PR Neupane ◽  
SB Pradhan ◽  
R Pathak
Keyword(s):  
Breast Carcinoma ◽  
Relevant Information ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Fine Needle ◽  
Triple Assessment ◽  
Grade Ii ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Grade Iii

Background: Invasive breast carcinoma is the most common carcinoma in women. Fine needle aspiration cytology is the important part of triple assessment of the palpable breast lump. Robinson’s cytological grading can be done in fine needle cytology smears of breast lump. The aim of this study is to grade breast tumor on cytology according to Robinson cytological grading and to correlate with histopathological grading.Materials and methods: This prospective study was done in Department of pathology, Bhaktapur Cancer Hospital from 1st April 2014 to 30thjuly 2015. A total of 58 cases of cytologically confirmed breast carcinoma were included in this study and correlated with histopathological findings. Robinson’s cytological grading was done on cytology smears and modified Bloom-Richardson grading was done on histological sections. Correlation between these two grading was done by using spearman’s correlation coefficient.Results: Cytologically, most common tumor was grade II (62.1%) followed by grade I (19%) and grade III (19%). Histologically, most common tumor was grade II (63.8%) followed by grade III (22.4%) and grade I (13.8%). High concordance rate was found in grade II tumor (80%) with absolute concordance being 65.9%. On cytology, cell dissociation and nuclear margin were determining features (p<0.005). Correlation between cytological grading and histological grading was statistically significant (p<0.005).Conclusion:  Robinson’s cytological grading is the easy grading method that can be done on cytology smears of the breast carcinoma to achieve relevant information regarding aggressiveness of the tumor and to plan for neoadjuvant chemotherapy preoperatively.

scholarly journals Diagnostic Role of Fine Needle Aspiration Cytology in the Breast Lump With its Correlation with Histopathology

1970 ◽  
Vol 14 (2) ◽  
pp. 65-69
Author(s):  
Hazara Khatun ◽  
Suraiya Enam ◽  
Maleeha Hussain ◽  
Monowara Begum
Keyword(s):  
False Negative ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Breast Lump ◽  
Medical College ◽  
False Positive Diagnosis ◽  
Diagnostic Role ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

This study was carried out to evaluate the accuracy of FNAC and its role in palpable breast lumps for the early surgical management in outdoor and indoor patients of Dhaka Medical College during the period of January to December 2000. FNAC was performed on 310 patients who presented with palpable breast lumps. Histopathology was available in 122 cases, among which cytologically diagnosed benign cases were 106 proved so histologically in 105 (99.05%) cases but catagorized correctly in 99 cases. There was false negative diagnosis in one case. All 14 cases diagnosed as malignant in cytological examination were confirmed as such histologically. Two cases reported as suspicious for malignancy in cytological diagnosis, was proved malignant histologically. False positive diagnosis was made in one case. The accuracy of FNAC in the diagnosis of breast lump is quite satisfactory and can be compared with histopathological diagnosis. DOI: http://dx.doi.org/10.3329/taj.v14i2.8388 TAJ 2001; 14(2): 65-69

scholarly journals Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020 ◽  
Vol 7 (5) ◽  
pp. 1452
Author(s):  
Sumedha Laul ◽  
Divish Saxena ◽  
Nitin Wasnik
Keyword(s):  
Final Diagnosis ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Malignant Breast ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclusions: Attributing factors for suspicion of malignant lumps are advanced age, fixity to surrounding structures, presence of ulceration and peau’d orange breast skin appearance. Although for confirmation of malignancy from a suspected breast lump requires either cytology or histopathology of the excised specimen.

scholarly journals Descriptive study of breast problems in women who present to the general outpatient of a tertiary hospital in eastern region of Nepal

2013 ◽  
Vol 11 (1) ◽  
pp. 33-37
Author(s):  
Rajani Giri ◽  
R Bhandari ◽  
I Mahato ◽  
M Poudel ◽  
S Kumari ◽  
...  
Keyword(s):  
Age Groups ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Tertiary Hospital ◽  
Outpatient Department ◽  
Breast Diseases ◽  
Eastern Region ◽  
Breast Abscess ◽  
Imaging Results ◽  
Needle Aspiration Cytology

Background: Breast problems are common among female patient attending general outpatient. Although the problem is expected to have significant morbidity, patients usually hide or present late for breast related problems in Nepal. Objective: To measure the pattern of breast diseases and its frequency and distribution in different age groups among patients attending general outpatient department at BPKIHS, Nepal. Methods: A crosssectional study was conducted in general outpatient department (GOPD) of B.P.Koirala Institute of Health Sciences (BPKIHS) during a period of six months. Women of all age groups presenting with breast problem were included. Clinical assessment, fine needle aspiration cytology (FNAC) and radiology were done. Mammography being unavailable at the hospital, ultrasonography was the preferred method of imaging. Results: Hundred cases of breast diseases were assessed. The benign breast disease (BBD) was the commonest finding (96%). Among BBD, fibroadenoma was the commonest (32%) followed by breast abscess (26%) and mastalgia (22%) including cyclic and non cyclic. The common age groups of involvement were 30-39 years for fibroadenoma, 20-29 years for breast abscess, 30-39 years for cyclic mastalgia, 40- 49 years for non cyclic mastalgia and 70-79 years for breast cancer. Conclusion: BBD is the most common breast problem in women. Among BBD, fibroadenoma was the most common. Health Renaissance, January-April 2013; Vol. 11 No.1; 33-37 DOI: http://dx.doi.org/10.3126/hren.v11i1.7599

scholarly journals Fine Needle Aspiration Cytology of Palpable Breast Lumps - Their Cytological Spectrum and Histopathological Correlation

KYAMC Journal ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 780-786
Author(s):  
Shaheen Akter ◽  
Md Jahidul Islam ◽  
Md Shariful Haque
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: With the advent of fine needle aspiration cytology (FNAC), the approach to diagnosis and management of breast lumps has been revolutionized and it has high sensitivity and specificity.Aim: In this study we analyze the spectrum of FNAC diagnoses in breast lumps and compare the diagnostic accuracy of fine FNAC in differentiating the benign and malignant lesions of breast lumps with histopathological correlation.Materials & Methods: Two years prospective study was conducted in our institution and in that 490 aspirations, including 6 bilateral were performed. Suppurative and inflammatory lesions were excluded from the total aspirates. The cytological diagnosis was classified into 3 groups benign, suspicious and malignant. After this reporting all the available 94 cases were later subjected to mastectomy or open/excision biopsy and followed-up by histopathological confirmation. Later diagnostic accuracy of cytology reporting was compared with that of histopathology.Results: A total of 490 FNAC cases were reported including 373 as benign, 4 as suspicious for carcinoma and 113 as carcinoma. Majorities were premenopausal females and commonest age group was 31-40 years. Among them only 94 cases were followed-up by histopathologic confirmation. In histopathological correlation study, we had accuracy rate of 100% for benign lesion and 92.10% for malignant lesion with false negative rate of 7.90% and false positive rate of zero with fine needle aspiration cytology in the diagnosis of palpable breast lump. The overall sensitivity of fine needle aspiration in diagnosing the palpable breast lump is 92.10%, specificity is 100%, positive predictive value is 100% and negative predictive value is 94.91%.Conclusion: FNAC in experienced hands is a very useful tool with very high specificity and rare false positive result. Sensitivity can be further improved with clinical and imaging correlation.KYAMC Journal Vol. 7, No.-2, Jan 2017, Page 780-786

scholarly journals A comparative clinicopathological study between ultrasonography, mammography, fine needle aspiration cytology and core needle biopsy of breast lump

2020 ◽  
Vol 7 (7) ◽  
pp. 2325
Author(s):  
Arnab Mandal ◽  
Pradipta Jana ◽  
Sabyasachi Bakshi ◽  
Ram Krishna Mandal
Keyword(s):  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Background: Early presentation and prompt diagnosis is the essential key in treatment of different variety of neoplastic as well as non-neoplastic breast disease. In this study usefulness of high-resolution ultrasonography (HRUSG), mammography, fine needle aspiration cytology (FNAC) and core needle biopsy in correlation with histopathological pattern, was assessed.Methods: After matching the criteria, 212 cases, were taken for this prospective, single center, observational study.Results: Out of 212 cases, 163 (76.88%) were benign lesions, 49 (23.11%) were malignant and 1 (0.47%) were of inflammatory pathology. Benign to malignant breast disease ratio was 3.3:1. Out of 49 malignant cases, 45 (91.83%) were ductal cell carcinoma and 4 (8.16%) was apocrine carcinoma. Maximum numbers of cancer patients were found in the 51-60-year age groups. The sensitivity, specificity, positive predictive value and negative predictive value of mammography in detecting carcinoma breast were 87.76%, 64.71%, 87.76% and 64.71% respectively. The sensitivity, specificity, positive predictive value and negative predictive value of HRUSG in detecting carcinoma breast were 85.71%, 90.18%, 72.41% and 95.45% respectively. Among benign lesions, 47 (28.83%) were diagnosed by mammography and 147 (90.18%) were diagnosed by HRUSG. When these modalities were combined, >95% of the lesions was diagnosed accurately.Conclusions: Ultra sound used liberally as an adjunct to mammography, increase the cancer detection rate. Core needle biopsy is found more accurate but FNAC have limited value in evaluation of benign breast lump. This study also proves that preoperative categorization of breast lesions is utmost important for management of the patient and this will help to avoid unnecessary surgical treatment.

scholarly journals The spectrum of palpable breast lesions- A cytopathological study of 1193 cases

2021 ◽  
Vol 7 (3) ◽  
pp. 144-149
Author(s):  
Manasa GC ◽  
◽  
Sneha SP ◽  
Adicherla Govardhan ◽  
◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Breast Cancer ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Introduction- The vast majority of the lesions that occur in the breast are benign. Much concern isgiven to malignant lesions of the breast because female breast cancer has now surpassed lungcancer as the leading cause of global cancer incidence in 2020. Fine needle aspiration cytology(FNAC) has good sensitivity, specificity and accuracy in the diagnosis of both neoplastic and non-neoplastic breast lump thereby assisting in early diagnosis and further management. The currentstudy was done to study the incidence and the different cytomorphological patterns of palpablebreast lumps by FNAC and consequently compare the results with studies in the literature.Materials and methods- This is a retrospective study conducted from January 2018 to December2020 in a tertiary care hospital. The three-year data is obtained from the records maintained in theFNA clinic. The patients were counselled before the procedure and informed consent was taken.Results- A total of 1193 breast lump cases were analysed in this 3-year study, there were 19 malepatients all of them presented with gynaecomastia and 1177 female patients. The patient’s agegroup ranged from 12 to 86 years. The commonest age group with the lesions 31-40 yearscomprising 326 cases (27.32%) followed 21-30 years age group in the second place with 307 cases(25.7%). Conclusion- In this study the most common benign neoplastic and malignant neoplasticbreast lumps are fibroadenoma and infiltrating ductal carcinoma respectively. Fibrocystic disease ofthe breast is the most common non-neoplastic breast lump.

scholarly journals Evaluation of Breast Lump by Fine Needle Aspiration Cytology

2017 ◽  
Vol 9 (2) ◽  
pp. 38-42
Author(s):  
Suman Poudel ◽  
S Ranabhat ◽  
B Parajuli ◽  
G Pun
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
College Teaching ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Significant Difference ◽  
Needle Aspiration Cytology

Introduction: Fine needle aspiration cytology (FNAC) is the important part of triple assessment in diagnosing the palpable breast lump. It categorizes the lesion into benign, malignant and its subtypes. It can also identify the residual diseases after treatment.Methods: It was a cross sectional descriptive study of cases of breast lump carried out during June 2015 to May 2016 in the Department of Pathology, Gandaki Medical College Teaching Hospital, Pokhara, Nepal. All the patients presenting in Pathology Department with history of breast lump were examined in detail. FNAC was done by standard procedure; smears were prepared and stained with Giemsa and pap for evaluation. Histopathology slides were stained with hematoxylin and eosin stain and evaluated by pathologists in Gandaki Medical College Teaching Hospital.Results: The study showed that, fibroadenoma of breast is the commonest benign lesion among the young populations. Only 13.11% of breast lump is malignant in the elderly population.Conclusion: FNAC is one of the safest and cheapest procedure that can be done in outpatient department for the diagnosis of breast lump. And there is no significant difference in diagnosis made by FNAC and histopatholgy examination. Journal of Gandaki Medical CollegeVolume, 09, Number 2, July December  2016, Page: 38-42

scholarly journals Fine needle aspiration cytology (FNAC) in pre-operative diagnosis of breast lesions in Kadapa region of Andhra Pradesh, India

2017 ◽  
Vol 4 (12) ◽  
pp. 4062
Author(s):  
Chakarala Obula Reddy ◽  
Garisa Chandra Mohana Reddy
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background: Various diagnostic methods have been developed to evaluate the palpable and non-palpable breast lesions, but Fine needle aspiration cytology of the palpable breast masses have become increasingly popular as a diagnostic technique to assess the breast lesions. To study the role of FNAC in diagnosis of breast lumps.Methods: 60 female patients (11-74 years age group) with palpable breast lump were utilized to study the role of Fine needle aspiration cytology for clinically palpable breast lump was carried out in Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh.Results: Fine needle aspiration cytology revealed benign in 22 patients, suspicious in 3 and 35 malignant lesions were 93.10% with false negative rate of 6.9% and false positive rate of 0%. The overall sensitivity of fine needle aspiration cytology in diagnosing the palpable breast lump in our study was 93.10%, specificity was 100%, positive predictive of 100% and negative predictive value of 90.47%.Conclusions: FNAC is easy to perform and painless procedure and standard tool for diagnosis of breast lumps with high percentage of true positives without virtual complications.

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