scholarly journals Deep vein thrombosis in a child with osteoarticular infection: A case report

2014 ◽  
Vol 9 (1) ◽  
pp. 52-55
Author(s):  
Devendra Shrestha ◽  
H Limbu ◽  
NB Thapa ◽  
AK Dhakal
Keyword(s):  
Deep Vein Thrombosis ◽  
Femoral Vein ◽  
Left Knee ◽  
Medical Sciences ◽  
Left Femur ◽  
Osteoarticular Infection ◽  
Vein Thrombosis ◽  
Osteoarticular Infections ◽  
Prolonged Hospital ◽  
Deep Vein

Acute osteoarticular infections are common in children and rarely complicated with deep vein thrombosis (DVT). This complication can cause significant morbidity and may even be fatal. Herein we report a ten year girl with deep vein thrombosis of left femoral vein who presented initially with septic arthritis of left knee and osteomyelitis of left femur. She required prolonged hospital admission and was managed with surgical debridement, antibiotics and anticoagulation. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-1, 52-55 DOI: http://dx.doi.org/10.3126/jcmsn.v9i1.9675

A murine model of deep vein thrombosis Characterization and validation in transgenic mice

2005 ◽  
Vol 94 (09) ◽  
pp. 498-503 ◽  
Author(s):  
Linda Szema ◽  
Chao-Ying Chen ◽  
Jeffrey P. Schwab ◽  
Gregory Schmeling ◽  
Brian C. Cooley
Keyword(s):  
Deep Vein Thrombosis ◽  
Murine Model ◽  
Femoral Vein ◽  
Previous History ◽  
Bed Rest ◽  
Major Surgery ◽  
Vein Thrombosis ◽  
Transgenic Lines ◽  
History Of ◽  
Deep Vein

SummaryDeep vein thrombosis (DVT) occurs with high prevalence in association with a number of risk factors, including major surgery, trauma, obesity, bed rest (>5 days), cancer, a previous history of DVT, and several predisposing prothrombotic mutations. A novel murine model of DVT was developed for applications to preclinical studies of transgenically constructed prothrombotic lines and evaluation of new antithrombotic therapies. A transient direct-current electrical injury was induced in the common femoral vein of adult C57Bl/6 mice. A non-occlusive thrombus grew, peaking in size at 30 min, and regressing by 60 min, as revealed by histomorphometric volume reconstruction of the clot. Pre-heparinization greatly reduced clot formation at 10, 30, and 60 min (p<0.01 versus non-heparinized). Homozygous FactorV Leiden mice (analogous to the clinical FactorV Leiden prothrombotic mutation) on a C57Bl/6 background had clot volumes more than twice those of wild-types at 30 min (0.121±0.018 mm3 vs. 0.052±0.008 mm3, respectively; p<0.01). Scanning electron microscopy revealed a clot surface dominated by fibrin strands, in contrast to arterial thrombi which showed a platelet-dominated structure. This new model of DVT presents a quantifiable approach for evaluating thrombosis-related murine transgenic lines and for comparatively evaluating new pharmacologic approaches for prevention of DVT.

Advantages of a Sequential Compression Device in Prevention of Deep Vein Thrombosis

1979 ◽  
Author(s):  
A.N. Nicolaides ◽  
J. Fernandas ◽  
A.V. Pollock
Keyword(s):  
Deep Vein Thrombosis ◽  
Femoral Vein ◽  
Test Group ◽  
Heparin Group ◽  
Similar Time ◽  
Vein Thrombosis ◽  
Compression Device ◽  
Fibrinogen Test ◽  
Group B ◽  
Deep Vein

A sequential compression device (SCD) (6 chambers) compressing the ankle, calf end thigh sequentially at 35, 30 and 20 mm Hg for 12 seconds in every minute produced a 240% increase in peak velocity in the femoral vein. A non-sequential device (NSD) inflated to 25 mm Hg with a similar time cycle produced only an 180% increase in blood velocity.The two devices were tested clinically; 250 surgical patients were randomised to 3 groups scanned with the 125 I-fibrinogen test. Group A: 7 days subcutaneous heparin. Group B: NSD for 24 hours. Group C: SCD for 24 hours. The SCD was found to be as effective as heparin during the period it was used and more effective than NSD in preventing deep vein thrombosis proximal to the calf.

Leiomyosarcoma of a Femoral Vein Misdiagnosed as Deep Vein Thrombosis

2009 ◽  
Vol 20 (5) ◽  
pp. 689-691 ◽  
Author(s):  
Shunya Shindo ◽  
Masatake Katsu ◽  
Shigeaki Kaga ◽  
Hidenori Inoue ◽  
Koji Ogata ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Femoral Vein ◽  
Vein Thrombosis ◽  
Deep Vein

scholarly journals COMPARISON OF LONG-TERM RESULTS OF FEMORAL VEIN LIGATION AND TRANSCATHETER THROMBOLYSIS IN THROMBOSIS OF THE FEMORAL SEGMENT

2019 ◽  
Vol 178 (5) ◽  
pp. 62-68
Author(s):  
Yu. A. Bezlepkin ◽  
I. N. Sonkin ◽  
A. V. Gusinskiy ◽  
O. V. Fionik ◽  
V. Yu. Melnik ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Pulmonary Thromboembolism ◽  
Femoral Vein ◽  
Detailed Comparison ◽  
Long Term Results ◽  
Superficial Femoral Vein ◽  
Vein Thrombosis ◽  
Catheter Directed Thrombolysis ◽  
Significant Difference ◽  
Deep Vein

INTRODUCTION. The problem of preventing massive pulmonary thromboembolism and post-thrombotic syndrome in deep vein thrombosis has been studied for a long period. The introduction of new treatments for deep vein thrombosis requires a detailed comparison of their effectiveness.The OBJECTIVE of this work was a comparative analysis of ligation of the superficial femoral vein and regional thrombolytic therapy.MATERIAL AND METHODS. A retrospective multicenter study involving 30 patients with femoproplite thrombosis, who had received catheter-directed thrombolysis or ligation of the superficial femoral vein, was performed. The investigated patients underwent inpatient treatment.RESULTS. The data on the effectiveness of both methods in preventing pulmonary thromboembolism were obtained. When comparing both groups, we revealed a statistically significant difference in the frequency of the development of PTS and the severity of its development in 1 year after treatment. With ligation vein, 73.3 and 6.7% in the thrombolysis group (p=0.0005).CONCLUSION. Regional thrombolysis was an effective treatment for deep vein thrombosis and prevention of PTS.The authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.

scholarly journals Unilateral Lower Extremity Swelling as an Unusual Presentation of Non-hodgkin’s B-cell Lymphoma

2021 ◽  
Author(s):  
Sepehr Sahraiyan ◽  
Mahsa Abbaszadeh ◽  
Pouyan Aminishakib ◽  
Rastegar Rahmani Tanha ◽  
Sahar Karimpour Reyhan
Keyword(s):  
Deep Vein Thrombosis ◽  
Physical Examination ◽  
B Cell ◽  
Doppler Ultrasonography ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Left Knee ◽  
Unusual Presentation ◽  
Vein Thrombosis ◽  
Deep Vein

Non-Hodgkin’s B-cell lymphoma is a hematological condition with different types based on clinical presentation, pathological features, and therapeutic response, like Diffuse Large B-cell Lymphoma (DLBCL), follicular lymphoma, and Chronic Lymphocytic Leukemia (CLL). We report A 33-year-old male presented with a complaint of unilateral leg swelling, firstly supposed to be a Deep Vein Thrombosis (DVT); however, in multiple Doppler ultrasonography, DVT was ruled out. The patient’s precise history revealed a swollen mass in the left knee region for two months that slowly enlarged and was confirmed with a physical examination. Doppler ultrasonography of the lower extremities conducted in our center presented no sign of deep vein thrombosis; however, it demonstrated some complex conglomerate lymph nodes in the left inguinal compressing the ipsilateral femoral and iliac vein. It also revealed bulky adenopathy, with a 95×65 mm left knee mass. The performed biopsy reported the existence of malignant lymphoma, suggesting the existence of DLBCL. Consequently, he was referred to a hematology/oncology department for appropriate treatment. This unusual presentation of DLBCL and the importance of noticing an accurate history taking and physical examination, instead of conducting unnecessary paraclinical tests (several Doppler ultrasonography in this case), have led us to report this case.

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