scholarly journals Spectrum of skin adnexal tumors with eccrineand apocrine differentiation – A single institution study of 40 cases with clinicopathological correlation

2015 ◽  
Vol 5 (9) ◽  
pp. 727-732
Author(s):  
P Vijayan ◽  
R Nayak

Background: Adnexal skin tumors are relatively rare and present diagnostic difficulties in view of the endless morphological spectrum, complex nomenclature and incomplete knowledge of their histogenesis. Since pathologists encounter these lesions rarely, accurate sub classification of these can be challenging. This study intends to study skin adnexal tumors with eccrine and apocrine differentiation with emphasis on their histomorphology.Materials and Methods:The present study is a five year retrospective study with comprehensive analysis of 40 cases of adnexal tumors of skin in a tertiary center in Karnataka, South India. These tumors were reclassified and subtyped according to WHO classification of skin tumors, 2006.Results and analysis:Out the 62 cases of adnexal tumors studied, 40 were tumors with eccrine and apocrine differentiation (77% benign and 23% malignant). Hidradenoma was the most common tumor comprising 37% of all tumors and 45% of the benign tumors followed byspiradenoma, cylindroma and chondroidsyringoma respectively. Head and neck region was the most common site of occurrence, and seventh decade was the most frequent age group of presentation. A definite female preponderance was noted. Pagets disease of the breast was the most common malignant tumor in this group comprising (10%). Conclusion: Histopathology is considered the gold standard in the diagnosis of these tumors and so a clear knowledge of the clinical presentation and histomorphology of these tumors is essential to make a correct diagnosis. A diagnostic logarithm based on histomorphology provides a logical approach in the subclassification of adnexal tumors.DOI:

2018 ◽  
Vol 27 (4) ◽  
pp. 457-463 ◽  
Author(s):  
Rūta Žulpaitė ◽  
Žymantas Jagelavičius ◽  
Ugnius Mickys ◽  
Ričardas Janilionis

Only 1% to 2% of meningiomas have primary extrameningeal location, which is mostly head and neck region. Primary pulmonary meningiomas (PPMs) are even more uncommon with up to 50 cases reported in the literature. Only 5 cases of PPM with confirmed or possible malignancy have been previously described. Three-grade classification of meningiomas with the accordingly growing risk of aggressive behavior of the tumor has been proposed by the World Health Organization. As it is based on correlations between morphological and clinical features of intracranial meningiomas, the analogous prediction of ectopic tumors prognosis remains questionable due to scarce number of cases. In this article, we present a rare case of PPM with rhabdoid features (World Health Organization grade III), which lacked other signs of malignancy. The patient is doing well for 2 years after the thoracoscopic wedge resection without evidence of the disease recurrence.


2020 ◽  
Vol 9 (10) ◽  
pp. e1519108461
Author(s):  
Rani Iani Costa Gonçalo ◽  
Cristiane Kalinne Santos Medeiros ◽  
Humberto Pereira Chaves Neto ◽  
Janaina Lessa de Moraes dos Santos ◽  
Adriano Rocha Germano ◽  
...  

Background: Osteosarcoma is a malignant neoplasm that occurs most often in long bones, with the head and neck region being rarely affected, accounting for less than 1% of all cancers in this region. Objective: To report a rare case of a large-extension osteosarcoma with emphasis on its clinical and diagnostic aspects. Case presentation: A 43-year-old woman presenting an intraoral exophytic lesion with involvement of other maxillofacial structures, such as nostril, zygoma and orbit. Despite the initial clinical diagnosis of actinomycosis, an incisional biopsy confirmed the histopathological diagnosis of osteosarcoma, showing a wide morphological variety. Conclusion: This case highlights the importance of clinical and histopathological findings for the correct diagnosis of osteosarcoma. Moreover, it shows that, although surgical resection is the primary treatment for this neoplasia, depending on the extent of the tumor and its proximity to vital anatomical structures, the most appropriate conduct is not always feasible.


2020 ◽  
Vol 17 (1) ◽  
pp. 63-65
Author(s):  
Anisha Joshi ◽  
Deeptara Pathak Thapa

Schwannomas/ neurilemmomas are benign tumors of nerve sheath arising from Schwann cells that form myelin sheath around peripheral nerves. They are usually solitary, slow growing and encapsulated lesions. Head and neck are the common sites. We report a case of a 38 years old Nepalese female who had presented with a solitary asymptomatic, slow growing nodule on the left side of the chin for the last three years. Dermoscopy of the lesion revealed arborizing vessels with brownish pigmentation overlying a whitish to pinkish background. Complete excision of the lesion was performed. Histopathological evaluation of the lesion revealed schwannoma. Though schwannomas are a rare diagnosis, they should be considered as a differential diagnosis of any unilateral, asymptomatic, slow growing nodule in the head and neck region. Dermoscopy is a useful tool which helps to differentiate schwannoma from other lesions. Histopathology is the gold standard for diagnosis and the treatment of choice is surgical excision.  


Author(s):  
Jayendiran S. ◽  
Jinu Vadakkanethu Iype ◽  
Srinivasa V.

<p class="abstract">Epidermoid cysts are frequently encountered cutaneous cysts. They are mostly tiny and benign swellings. But rarely they can grow huge in size and malignant transformation can also occur occasionally. Cosmetic disfigurement is also another important concern especially in head and neck region. We report a case of earlobe epidermoid cyst, a location where very few cases have been described in the literature. The cyst was completely excised and the wound was closed with nylon 4/0. Histopathological examination confirmed the diagnosis of an epidermoid cyst. The patient did not have any signs of recurrence even after six months postoperatively. Due to the possibility of malignant transformation and to ensure correct diagnosis, we consider that histopathological examination is necessary for all cysts although the clinical diagnosis could be enough.</p>


Author(s):  
Juliana Rodrigues Rozatto ◽  
Alan Motta Do Canto ◽  
Paulo Henrique Braz-Silva ◽  
Ronaldo Rodrigues Freitas

The ameloblastoma is a locally aggressive odontogenic tumour that has high recurrence rates. It rarely presents a histological aspect similar to the odontogenic keratocyst, because of the presence of keratinised areas. This study aimed to report a case of ameloblastoma in the mandible, diagnosed and treated incorrectly as an odontogenic keratocyst because of unusual macroscopic characteristics and rare histological aspects that impaired a correct diagnosis. Case report: A 57-year-old female patient, presenting an asymptomatic lesion at the left mandibular angle, was treated by incisional biopsy and decompression. The histological sections showed an aspect suggesting odontogenic keratocyst. At the 3-year postoperative period, the patient returned with a new lesion on the left side of the mandible and was then subjected to curettage. The histological sections showed a pattern of ameloblastoma and, because of this, the patient remained with a 6-month follow-up. At the 4-year postoperative period after the second operation, the patient returned with a new recurrence. The biopsy showed an ameloblastoma and the patient was submitted to mandibular resection and reconstruction as treatment. After the final procedure, the recovery was uneventful and the patient is now undergoing a postoperative period of four years, without recurrences. Conclusion: This case highlights the importance of carrying out a proper biopsy and an adequate examination by a specialised professional, because of the possibility of atypical lesions occurring restricted to the head and neck region. 


2020 ◽  
Vol 13 (1) ◽  
pp. 78-82
Author(s):  
Brihaspati Sigdel ◽  
Rajesh Maharjhan ◽  
Tulika Dubey ◽  
Bhima Neupane

Hemangiomas of the head and neck region comprise about 60 to 70% of all benign tumors. Intramuscular hemangioma is a rare, slow-growing, angiomatous tumor. We report a rare case of an Intramuscular Hemangioma of Right sternocleidomastoid muscle in a six years old girl presenting for four years and with extensive involvement necessitating excision. Microscopic excision reduces the risk of recurrence.


Author(s):  
Gabriel Ángel Martos-Moreno ◽  
Inmaculada de Prada ◽  
Cristina Riñón ◽  
Jesús Argente

AbstractRhabdomiomas are rare mesenchymal benign tumors of striated muscle origin. Setting aside the cardiac (most atrial) rhabdomiomas typically associated to neurocutaneous syndromes (tuberous sclerosis), extracardiac rhabdomyomas appear clinically as a subcutaneous nodule or as a submucosal polypoid lesion. Among them, three main histologic subtypes can be differentiated on the basis of the degree of tumor differentiation: 1) fetal rhabdomioma, usually diagnosed during childhood and almost exclusively located in the in the head and neck region with rare reports in other locations; 2) adult rhabdomioma; and 3) genital rhabdomioma, reported to occur in the lower genital tract of young and middle-aged women and, exceptionally, in children (5).


1988 ◽  
Vol 102 (10) ◽  
pp. 909-913 ◽  
Author(s):  
Lesley A. Smallman ◽  
Jennifer A. Young ◽  
J. Oates ◽  
D. W. Proops ◽  
A. P. Johnson

AbstractAspirates were obtained from 142 masses in 120 patients who presented with palpable swellings in the head and neck region. 120 specimens (84.51 per cent) were adequate for diagnostic purposes and the remaining 22 (15.49 per cent) were unsatisfactory. Final diagnosis was based on resection histology in 87 cases and close clinical follow-up in 55 patients. The overall sensitivity and specificity including unsatisfactory aspirates was 81.37 per cent and 93 per cent respectively (if the technically inadequate specimens were deleted 98.81 per cent and 94.44 per cent). In comparison with the final diagnosis typing of malignant tumours was possible in 58.33 per cent. The correct diagnosis was made in 63.89 per cent of benign lesions.


Author(s):  
Aliyu Daniel ◽  
K. R. Iseh ◽  
J. H. Solomon ◽  
Olawole W. Olalekan ◽  
Braimah R. Oyebunmi ◽  
...  

Introduction: Virchow first describes Myxomas in 1871; they are benign tumors of primitive indifferent mesenchyme that have preference for the cardiac muscles, genitourinary tract, gastrointestinal tract, liver and spleen. The rarity of the tumor, especially in the head and neck region makes us to report this case. Case Report: A 16-year-old male secondary student who presented with a 9-year history of painless progressive submandibular swelling, no extension to the mouth. Examination revealed a huge fungating submandibular mass, 20 cm x 16 cm x10 cm in dimension, mobile, non-tender and firm in consistency. Other findings were unremarkable, and routine hematological and biochemical tests were all within normal limits. He subsequently had excision of the mass (weighs 950 g) under general anesthesia via an elective tracheostomy with split thickness skin grafting of the exposed strap muscles. Histopathological report revealed cutaneous myxoma. Conclusion: Cutaneous myxoma of the Head and Neck region is presented for its rarity, and although is a histologically benign neoplasm, treatment is extremely challenging with high incidence of recurrence.


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