scholarly journals Prevalence and Clinical Manifestations of Helicobacter Pylori with Reference to Histopathological Diagnosis

2020 ◽  
Vol 18 (1) ◽  
pp. 64-67
Author(s):  
R Makaju ◽  
B. Dhakal ◽  
R. Dhakal
Keyword(s):  
Helicobacter Pylori ◽  
Acute Abdomen ◽  
Reflux Esophagitis ◽  
Clinical Manifestations ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
Histopathological Diagnosis ◽  
Female Ratio ◽  
Steep Decline ◽  
Upper Gastrointestinal

Background Helicobacter pylori infection is on a steep decline in most of the developed countries; however, in developing countries like Nepal such steep decline is not seen. This may be due to failure of treatment regimens and emergence of drug resistance. Our previous study done in 2004/2005 showed 38% prevalence of Helicobacter pylori. The present study has been conducted to review the prevalence and clinical diagnosis of Helicobacter pylori with reference to histo-pathological diagnosis. Method This was retrospective study done at Dhulikhel Hospital, Kathmandu University Hospital over a period of 13 years from January 2006 to December 2018. Helicobacter pylori proven cases were retrospectively analyzed with clinical features and endoscopy findings. The clinical picture were categorized into antral gastritis, gastroduodenits, erosive duodenitis, acid peptic disease, reflux esophagitis, hiatal hernia, polyp, ulcer (gastric and duodenal), acute abdomen, upper gastrointestinal bleeding and malignancy. Result A total of 1624 upper gastrointestinal endoscopy biopsies were taken during the study period. Helicobacter pylori infection was seen in 618 (38.0%) cases out of 1624 cases. Helicobacter pylori were seen in 349 male and 269 female patients with male to female ratio of 1.29:1. Clinically, gastritis 210 (41.4%), acid peptic disease74 (42.7%), gastroduodenitis 46 (37.7%), reflux esophagitis 38 (52.7%), gastric ulcer 48 (28.4%), duodenal ulcer 34 (53.1%) and acute abdomen 50 (42.3%) cases were seen respectively. Conclusion Most commonly Helicobacter pylori cause chronic gastritis in our context. There is no significant change in prevalence of Helicobacter pylori infection as compared to our previous study (2004/05). This needs proper management of Helicobacter pylori infection to prevent serious complication such as gastric cancer in our part of the world.

scholarly journals The Association between Helicobacter Pylori Infection and Insulin Resistance

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Dr. Reda M. Al-Badawy
Keyword(s):  
Insulin Resistance ◽  
Helicobacter Pylori ◽  
Mean Value ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Significant Difference ◽  
H Pylori ◽  
Group B

Introduction: Helicobacter pylori are associated with severe gastrointestinal pathologies. Moreover, it is associated with other conditions such as atherosclerosis, insulin resistance, diabetes mellitus and some autoimmune diseases. The purpose of this study is to search the relation between Helicobacter pylori infection and Insulin Resistance. Methods: Ninety patients complaining of dyspepsia was selected from Gastroenterology, Hepatology and Infectious Diseases Department, Benha University Hospital. The patients were divided into two groups with matching age, sex and the basic laboratory investigations results. Group (A) patients were Helicobacter pylori-positive. Group (B) patients were Helicobacter pylori negative based on endoscopic findings and confirmed by histopathological diagnosis and exclusion of other causes of dyspepsia. Insulin resistance was compared between the two groups. Results: In the present study, there was statistically significant association between Helicobacter pylori positive patients (51/90; 56.7%) and insulin resistance (IR) compared to Helicobacter pylori negative patients (39/90; 43.3%) (P value <0.001). The mean value of IR was 3.6 ± 0.58, 2.2 ± 0.36 respectively for Helicobacter pylori positive and Helicobacter pylori negative patients. There was no statistical significant difference between Helicobacter pylori positive and Helicobacter Pylori negative patients as regard to other investigations (P value >0.05). Conclusion: Insulin resistance has a role in the chronicity of H. pylori infection and the reduction of IR will lead to a better response of therapy in these patients.

Reflux Esophagitis and Helicobacter Pylori Infection in Patients with Systemic Scleroderma

2006 ◽  
Vol 63 (5) ◽  
pp. AB138
Author(s):  
Kanako Yamaguchi ◽  
Ryuichi Iwakiri ◽  
Akiko Danjyo ◽  
Yasuhisa Sakata ◽  
Hibiki Ootani ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Reflux Esophagitis ◽  
Helicobacter Pylori Infection ◽  
Systemic Scleroderma

Prospective Assessment of Helicobacter Pylori Infection and Gastric Pathologies in Sidi Bel Abbes region, Western Algeria

2018 ◽  
Vol 7 (5) ◽  
pp. 217-224
Author(s):  
Zouaouia Chama ◽  
Khedoudj Kanoun ◽  
Fatima Zohra Elkadi ◽  
Kara Turqui Douidi ◽  
Noria Harir ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Histological Study ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
Infection Prevalence ◽  
Gastric Diseases ◽  
Number Of Patients ◽  
H Pylori ◽  
The Impact

Helicobacter pylori infection concerns half of the world’s population, mainly in developing countries. It causes several gastrodudenal pathologies such as gastritis, ulcer and gastric adenocarcinoma. The aim of our study was to determine the prevalence of H.pylori infection and to assess the impact of different epidemiological factors as well as principal gastric diseases associ-ated to this infection. We underwent a prospective study during 18 months (month 2016-month 2017) which implicated 201 symptomatic patients for gastric fiboptic endoscopy at the level of Sidi Bel Abbes University hospital. We collected patients’ biopsies to perform a histological study and H. pylori culture. H. pylori identification was carried out based on bacteriological and biochemical analysis. The middle age of our population was (47.29 ±15.97ans) and the sex-ratio =0,8. The global prevalence of Helicobacter pylori infection is of 61.2% (123/201). This rate, after a statistic analysis, seems to be significantly related to age. It is particularly high especially for patients belonging to age range (20-30)-(51-60) years. The gender did not affect the infection prevalence that is more frequent in the gastritis case. We noticed also that HP infection prevalence was important in SBA the hospital. The range age (20-30)-(51-60) years had the highest prevalence of H. pylori and of gastritis which might be a risky ground of gastric cancer appearance. The ulcer pathology maximal rate concerned the group of 51 to 60 years. Above this age, this rate dropped whereas the number of patients suffering from gastric cancer, which presents an important rate in our study, increase for the group of 61-70 years.

scholarly journals Epidemiology of upper gastrointestinal bleeding and Helicobacter pylori infection: review of 3,488 Thai patients

2017 ◽  
Vol 9 (1) ◽  
pp. 87-93
Author(s):  
Sakolwan Suchartlikitwong ◽  
Kamolyut Lapumnuaypol ◽  
Rungsun Rerknimitr ◽  
Duangporn Werawatganon
Keyword(s):  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Gastrointestinal Bleeding ◽  
Upper Gastrointestinal Bleeding ◽  
Helicobacter Pylori Infection ◽  
Exclusion Criteria ◽  
Common Causes ◽  
Mucosal Lesions ◽  
H Pylori ◽  
Upper Gastrointestinal

Abstract Background The current epidemiology of upper gastrointestinal bleeding (UGIB) in Thailand is poorly understood and the reported prevalence of Helicobacter pylori infection is outdated. Objectives To investigate the etiologies of UGIB and prevalence of H. pylori infection in Thailand, including its association with UGIB. Methods We retrieved information regarding patients attending the endoscopic unit of King Chulalongkorn Memorial Hospital from June 2007 to January 2013. A database search using keywords “upper gastrointestinal bleeding” and “iron deficiency” was used. From 4,454 diagnoses, after exclusion criteria, 3,488 patients (2,042 male (58.5%) and 1,446 female (41.5%); mean age 63.3 ± 15.94 years, range 13–103 years) were included. Results The three most common causes of UGIB were peptic ulcer (38.2%), nonulcer-mucosal lesions (23.4%), and esophageal-related causes (20.4%). The 5 year-incidence of H. pylori was 25%–30%. The overall prevalence was 27%. The prevalence of H. pylori infection was found to decrease with age from 43.8% at <40 years to 21.7% at >79 years old. H. pylori infection was significantly associated with duodenal and gastroduodenal ulcers. Cirrhosis and nonulcer-mucosal lesions were significantly unrelated to H. pylori infection. Patients with concurrent cirrhosis with peptic ulcer were found to be negative for H. pylori infection. Conclusion Peptic ulcer is the leading cause of UGIB in Thailand. However, its incidence is declining. Patients who presented to hospital with UGIB were older, compared with those a decade ago. H. pylori infection plays an important role in UGIB and its incidence was stable during the past 5 years.

scholarly journals Helicobacter Pylori Infection and Upper Gastrointestinal Disease

2012 ◽  
Vol 29 (1) ◽  
Author(s):  
Marina Dinić ◽  
Dobrila Đorđević ◽  
Gordana Tasić ◽  
Branislava Kocić ◽  
Milena Bogdanović
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Disease ◽  
Helicobacter Pylori Infection ◽  
Upper Gastrointestinal
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