scholarly journals The Association between Helicobacter Pylori Infection and Insulin Resistance

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Dr. Reda M. Al-Badawy
Keyword(s):  
Insulin Resistance ◽  
Helicobacter Pylori ◽  
Mean Value ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
P Value ◽  
Histopathological Diagnosis ◽  
Significant Difference ◽  
H Pylori ◽  
Group B

Introduction: Helicobacter pylori are associated with severe gastrointestinal pathologies. Moreover, it is associated with other conditions such as atherosclerosis, insulin resistance, diabetes mellitus and some autoimmune diseases. The purpose of this study is to search the relation between Helicobacter pylori infection and Insulin Resistance. Methods: Ninety patients complaining of dyspepsia was selected from Gastroenterology, Hepatology and Infectious Diseases Department, Benha University Hospital. The patients were divided into two groups with matching age, sex and the basic laboratory investigations results. Group (A) patients were Helicobacter pylori-positive. Group (B) patients were Helicobacter pylori negative based on endoscopic findings and confirmed by histopathological diagnosis and exclusion of other causes of dyspepsia. Insulin resistance was compared between the two groups. Results: In the present study, there was statistically significant association between Helicobacter pylori positive patients (51/90; 56.7%) and insulin resistance (IR) compared to Helicobacter pylori negative patients (39/90; 43.3%) (P value <0.001). The mean value of IR was 3.6 ± 0.58, 2.2 ± 0.36 respectively for Helicobacter pylori positive and Helicobacter pylori negative patients. There was no statistical significant difference between Helicobacter pylori positive and Helicobacter Pylori negative patients as regard to other investigations (P value >0.05). Conclusion: Insulin resistance has a role in the chronicity of H. pylori infection and the reduction of IR will lead to a better response of therapy in these patients.

scholarly journals Helicobacter pylori infection according to ABO blood group among blood donors in Kosovo

2011 ◽  
Vol 1 (2) ◽  
pp. 83-89 ◽  
Author(s):  
Bukurije Zhubi ◽  
Zana Baruti-Gafurri ◽  
Ymer Mekaj ◽  
Mimoza Zhubi ◽  
Idriz Merovci ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Blood Group ◽  
Blood Donors ◽  
Mean Value ◽  
Blood Groups ◽  
Helicobacter Pylori Infection ◽  
Igg Antibody ◽  
Significant Difference ◽  
Rhesus Blood Group ◽  
H Pylori

Introduction: Numerous studies have reported a high prevalence of Helicobacter pylori infection among healthy and non-healthy persons in different places. The Aim of the study is to investigate the seroprevalence of H. pylori infection among Kosovo’s Blood donor associated with ABO/Rhesus blood group.Methods: 671 blood donors are tested for H. pylori antibodies and results are classifi ed by way of donation, age, gender, blood groups and education level. Serum antibodies are analyzed by Enzyme Linked Fluorescent Assay test for H. pylori IgG with Biomerieux HPY-VIDAS.Results: The frequency of IgG antibody for H. pylori among healthy blood donors is 56.9%, there is not found any difference between voluntary and non-voluntary blood donors (57.4% respectively 56.3%)(OR=1.05; 95% CI 0.76 to 1.43; p=0.8). H pylori IgG antibodies positive are detected in 57.0 % ( 126 of 221) of women, compared with 56.9 % ( 256 of 450) of men(OR=0.99; 95% CI 0.72 to 1.38; p=0.96). Serpositive donors are older than seronegative ones (31.9 years, respectively 29.5 years, p=0.02). Mean value of IgG antibody of H. pylori is 3.61 with no significant difference between males and females (3.72 respectively 3.44; p=0.2). The seroprevalence of H. pylori infection is similar among blood groups: O (57.4%), A (56.2%), B (59.6%), AB (51.4%), RhD positive (56.7%) and RhD negative (58.3%).Conclusions: The seropositivity of H. pylori is moderately higher in the non voluntary and familiar blood donors among the total Kosovo blood donors. There is not found a significant relationship between infection with H. pylori and ABO/Rhesus blood group among blood donors.

scholarly journals Relationship of Halitosis with Gastric Helicobacter Pylori Infection

2021 ◽  
Vol 15 (7) ◽  
pp. 2285-2288
Author(s):  
Rakhshinda Jabeen ◽  
Ajmaal Jami ◽  
Aiman Shahab ◽  
Armash Shahab
Keyword(s):  
Helicobacter Pylori ◽  
Epigastric Pain ◽  
Human Condition ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
Clear Correlation ◽  
P Value ◽  
Pathophysiological Mechanism ◽  
H Pylori ◽  
Relationship Of

Background: Halitosis is a common human condition; however, the pathophysiological mechanism of halitosis is still unclear. Halitosis is mostly attributed with oral pathological conditions, in addition, halitosis resulting from gastrointestinal disorders is not rare either. Halitosis is often reported with symptoms related to Helicobacter pylori infection, epigastric pain and gastroesophageal reflux disease. Objective: Halitosis can stem from a number of gastric conditions and one of the most common causes of halitosis include the presence of a gastric infection with Helicobacter pylori. This study was conducted to evaluate the incidence ofhalitosis in patients presenting with Helicobacter pylori infection and epigastric pain. Additionally, to review whether there is a correlation between H pylori infection and halitosis; moreover, to determine whether halitosis is a valid indication for H pylori infection. Methods and Materials: This case control, comparative study was done at Medicine department of Isra University hospital and Civil hospital, Karachi during the period of January 2019 to December 2019. Participants were enrolled only after taking verbal and signed consent. Prior permission from the hospital management was taken as well. Result: Halitosis and H pylori are statistically significant with p value of 0.026. There was a clear correlation between halitosis and H pylori infection, and it may be a common contributor to halitosis.

scholarly journals COBALAMIN DEFICIENCY

2016 ◽  
Vol 23 (02) ◽  
pp. 176-181
Author(s):  
Shumaila Shaikh ◽  
Azhar Memon ◽  
Muhammad Atif Ata ◽  
Haji Khan Khoharo
Keyword(s):  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
University Hospital ◽  
Cobalamin Deficiency ◽  
P Value ◽  
Significant Difference ◽  
Design Case ◽  
H Pylori ◽  
Control Study

Objectives: The present study aims to evaluate the serum cobalamin inHelicobacter pylori (H. pylori) infected patients. Study Design: Case control study. Place andDuration: Department of Medicine, Isra University Hospital Hyderabad from March 2013- April2014. Methodology: A sample of 109 subjects including Helicobacter pylori positive subjectsand controls were selected according to study criteria. Centrifugation of blood was performedat 4000 rpm for 10 minutes and sera were stored at -20oC. Blood sera were used for H. pyloriserological testing. Blood counting was performed on hematoanalyzer. Cobas e411 analyzerwas used for detection of cobalamin. 64 kD H. pylori antigens was detected by ELISA. Thedata was entered into SPSS version 21.0. (IBM, Incorporation, USA) A 2-tailed p-value of ≤0.05was considered significant for statistical analysis. Results: Of total 109, 54.1% (n=59) wereH. pylori seropositive cases and others were controls i.e. 45.9% (n=50). Cases and controlsshowed cobalamin levels of 290±49.3 vs. 351±32.9 pg/ml respectively (p=0.0001). Red bloodcell indices were found to show statistically significant difference between cases and controls(p=0.001). Conclusion: Serum cobalamin deficiency was noted in both Helicobacter pyloripositive and controls, however deficiency was more pronounced in Helicobacter pylori positivesubjects.

Prospective Assessment of Helicobacter Pylori Infection and Gastric Pathologies in Sidi Bel Abbes region, Western Algeria

2018 ◽  
Vol 7 (5) ◽  
pp. 217-224
Author(s):  
Zouaouia Chama ◽  
Khedoudj Kanoun ◽  
Fatima Zohra Elkadi ◽  
Kara Turqui Douidi ◽  
Noria Harir ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Histological Study ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
Infection Prevalence ◽  
Gastric Diseases ◽  
Number Of Patients ◽  
H Pylori ◽  
The Impact

Helicobacter pylori infection concerns half of the world’s population, mainly in developing countries. It causes several gastrodudenal pathologies such as gastritis, ulcer and gastric adenocarcinoma. The aim of our study was to determine the prevalence of H.pylori infection and to assess the impact of different epidemiological factors as well as principal gastric diseases associ-ated to this infection. We underwent a prospective study during 18 months (month 2016-month 2017) which implicated 201 symptomatic patients for gastric fiboptic endoscopy at the level of Sidi Bel Abbes University hospital. We collected patients’ biopsies to perform a histological study and H. pylori culture. H. pylori identification was carried out based on bacteriological and biochemical analysis. The middle age of our population was (47.29 ±15.97ans) and the sex-ratio =0,8. The global prevalence of Helicobacter pylori infection is of 61.2% (123/201). This rate, after a statistic analysis, seems to be significantly related to age. It is particularly high especially for patients belonging to age range (20-30)-(51-60) years. The gender did not affect the infection prevalence that is more frequent in the gastritis case. We noticed also that HP infection prevalence was important in SBA the hospital. The range age (20-30)-(51-60) years had the highest prevalence of H. pylori and of gastritis which might be a risky ground of gastric cancer appearance. The ulcer pathology maximal rate concerned the group of 51 to 60 years. Above this age, this rate dropped whereas the number of patients suffering from gastric cancer, which presents an important rate in our study, increase for the group of 61-70 years.

scholarly journals Prevalence of Helicobacter Pylori Infection and Associated Factors Among Gastritis Patents in Yekatit 12 Teaching Hospital Addis Ababa Ethiopia

2020 ◽  
Author(s):  
Awraris Hailu ◽  
Bekureamanuel Sileshi ◽  
Hazaratali Panari
Keyword(s):  
Helicobacter Pylori ◽  
Teaching Hospital ◽  
Rural Areas ◽  
Associated Factors ◽  
Addis Ababa ◽  
Helicobacter Pylori Infection ◽  
Work Place ◽  
P Value ◽  
Hand Wash ◽  
H Pylori

Abstract Introduction: Helicobacter pylori colonize the stomach of about ~50% of the world’s human population and infection is more in clients with dyspeptic conditions and its associated with the severity of gastritis. The present study revealed that the magnitude of H. Pylori and burden of the bacterial infection as well as the contribution of H. Pylori for gastritis and also assesses the current prevalence of H. Pylori infection.Objective: To evaluate the prevalence of Helicobacter Pylori infection and associated factors among gastritis patents in Yekatit 12 Hospital.Methodology: An institutional based cross-sectional study was conducted in Yekatit 12 teaching hospital Addis Ababa city, Ethiopia. The participants were those patients come to the hospital for treatment of gastritis and send to the laboratory to confirm Helicobacter pylori infection in the data collection period. A total of 394 participants were interviewed by using a structured pre tested questionnaire. The data were coded and entered into Epi Data 3.1 version , cleaned and exported to version 20, SPSS. Multiple Logistic regression was used to estimate Adjusted (AORs) with a 95% confidence interval (CI) of positive responses to the different risk factors. P-value < 0.05 was considered as significant.Result: The total occurrence of H. Pylori in observers was 25.9%. Regarding income of family, those participants who have less income and living in rural areas were extra prone to be infected with H. Pylori (AOR=5.857, CI 95% = 1.389-24.686, P = 0.016 and AOR=3.663, CI 95% = 1.068-12.557, P =0.039) respectively. Further, the prevalence of study was significant association with participants who had experience of gastrointestinal illness, mouth to mouth kissing, unable to hand wash regularly before meal and after latrine used (AOR=4.270, 95%CI=1.785-10.21, P=0.01, AOR=53.085, 95%CI=16.185-174.114, P=0.000, AOR=7.316, 95%CI=1.944-27.536, P=0.003, AOR=3.374, 95%CI=1.024-11.114, P=0.046) respectively.Conclusion and recommendation: The finding shows that H. Pylori infection was significantly associated with occupational status,gender, smoking tobacco and hand washing regularly before meal and after toilet. I recommend making clean and saving the work place; regular hand wash, before food preparation, before feeding and after latrine. A health professional should give health education by using different media about the transition and health biro also should give emphases.

scholarly journals Seroprevalence of Helicobacter pylori in patients with colon adenomas in a brazilian university hospital

2009 ◽  
Vol 46 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Abadia Gilda Buso ◽  
Haroldo Luis Oliva Gomes Rocha ◽  
Débora Miranda Diogo ◽  
Priscila Miranda Diogo ◽  
Augusto Diogo-Filho
Keyword(s):  
Helicobacter Pylori ◽  
Solid Phase ◽  
Positive Association ◽  
University Hospital ◽  
Igg Antibody ◽  
Chi Square ◽  
Colon Adenomas ◽  
Colonic Adenomas ◽  
Significant Difference ◽  
H Pylori

CONTEXT: The association between Helicobacter pylori infection and colon neoplasia has been the subject of recent investigations which have produced controversial results. OBJECTIVE: To evaluate the prevalence of H. pylori infection in patients with colonic adenomas and also in patients whose colonoscopy exams were normal. METHODS: After colonoscopy, the individuals were distributed into two groups: patients with colon adenomas (cases) and patients whose colons were normal (controls). The groups were similar regarding age and gender. The individuals of both groups were subjected to a dosage of IgG antibody against H. pylori. The dosage was applied according to the solid phase, chemiluminescent immunometric assay. The chi-square test was used to analyze the data. RESULTS: There were 30 men and 64 women in each group (94 cases and 94 controls). The mean age of the cases was 59.79 ± 12.25 years and that of the controls was 58.98 ± 11.55 years. The H. pylori serology was positive for 66 (70.21%) of the cases and for 51 (54.25%) of the controls. There was a significant difference (P = 0.024). The odds ratio was 1.98 (CI 95%, 0.82-3.15). The prevalence of H. pylori in cases and controls according to gender, histological type and location of the colon lesions showed a significant difference only among women (P = 0.03), among patients with tubular adenomas (P = 0.03), and in those with distal adenomas (P = 0.038). CONCLUSION: There is a positive association between H. pylori infection and colonic adenomas. This association is more evident in women, especially for tubular adenomas and distal colonic location.

scholarly journals The Magnitude and associated factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji Hospital, Southeast Ethiopia

2020 ◽  
Author(s):  
Dagaga Goboto Kenea ◽  
Mesfin Negawo ◽  
Firaol Kitila Lemessa ◽  
Solomon Tejineh
Keyword(s):  
Helicobacter Pylori ◽  
Alcohol Drinking ◽  
Intestinal Parasites ◽  
Helicobacter Pylori Infection ◽  
P Value ◽  
Cross Sectional ◽  
Gastrointestinal Complications ◽  
Ulcer Disease ◽  
Southeast Ethiopia ◽  
H Pylori

Abstract Background: Helicobacter pylori infection is the most common chronic bacterial infection and there were approximately 4.4 billion individuals with H pylori infection worldwide. Among those, hundreds of millions of people develop peptic ulcer disease during their lifetime and still tens of millions might progress to gastric cancer. Hence, early information is very important to prevent upper gastrointestinal complications. Consequently, the current study aimed to assess the magnitude and associated risk factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji hospital, Southeast Ethiopia.Methods: A hospital-based cross-sectional study involving 348 adult dyspeptic patients attending Bokoji hospital was carried out from July 16 to October 31, 2019. About 50 mg of fresh stool and 60 µl of capillary blood were collected from each dyspeptic patient and analyzed for detection of Helicobacter pylori antigens, presence of intestinal parasites and ABO blood grouping respectively. Data were entered using Epi Info 7 and Statistical analysis was done using SPSS version 21 and a p-value less than 0.05 was considered as statistically significant.Results: The overall magnitude of Helicobacter pylori infection was 47.7%. The magnitude of H. pylori infection was almost two times higher in patients who do not have a habit of handwashing after toilet visit than those who wash their hand's habit of handwashing after visiting toilet (AOR 2.241, 95% CI (1.410, 3.563) and alcohol drinking habit (AOR 1.796, 95% CI (1.087, 2.968). Conclusions: The magnitude of H. pylori was high in the study area and associated with handwashing habits after toilet use and alcohol drinking habits. Therefore, the community could be educated on the handwashing habit to minimize H. pylori infections.

scholarly journals Atorvastatin in Helicobacter Pylori Treatment: A Randomized Controlled Trial and Review

2021 ◽  
Author(s):  
Mohammad Reza Mohammad Hoseini Azar ◽  
Parham Porteghali ◽  
Amin Sedokani
Keyword(s):  
Helicobacter Pylori ◽  
Standard Treatment ◽  
Controlled Trial ◽  
Intervention Group ◽  
Trial Registration ◽  
Control Group ◽  
P Value ◽  
Bismuth Subcitrate ◽  
Significant Difference ◽  
H Pylori

Abstract Background: Considering the increase in drug resistance over time to Helicobacter pylori treatment relying on the anti-inflammatory and antibacterial effects of atorvastatin to increase the success rate of H. pylori eradication, we examined the effect of adding atorvastatin to standard treatment of H. pylori eradication.Results: A total of 186 symptomatic patients who had been diagnosed with Helicobacter pylori infection and tested for H. pylori eradication were examined by a pathological response or positive urea breath test. Patients who received atorvastatin in addition to standard treatment were also identified based on a table of random numbers. Standard treatment included a 240mg bismuth subcitrate tablet, a 40mg pantoprazole tablet, a 500mg metronidazole tablet, and 2 capsules of 500mg amoxicillin, all taken BID for 14 days. After 4 weeks of treatment, all patients underwent stool testing for H. pylori fecal antigen. If the test was positive, the request was considered a failure of treatment, and if the test was negative, it was considered a successful eradication of H. pylori. The clinical trial registration code for this study is IRCT20190823044589N1. The eradication rate of H. pylori was 80% in the control group and 80.9% in the intervention group, which did not show a statistically significant difference between the two groups (P-value=0.971).Conclusion: Adding atorvastatin to 4-drug regimen of PPI, bismuth subcitrate, amoxicillin, and metronidazole as the first line of treatment for H. pylori eradication is ineffective.Trial registration: IRCT, IRCT20190823044589N1. Registered 28 December 2019 - Retrospectively registered, https://en.irct.ir/trial/41734

scholarly journals Helicobacter pylori infection among type 2 diabetics: a case control study

2020 ◽  
Vol 8 (3) ◽  
pp. 1047
Author(s):  
Hafiz Qazi Muhammad Amir ◽  
Omaila Ikram ◽  
Muhammad Tayyab Zia ◽  
Fareha Kashan Theba ◽  
Naila Ikram ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Case Control Study ◽  
Case Control ◽  
Helicobacter Pylori Infection ◽  
P Value ◽  
Type 2 Diabetics ◽  
Dyspeptic Symptoms ◽  
H Pylori ◽  
Control Study

Background: Helicobacter pylori infection has been associated with hyperglycemia among type 2 diabetics. The objective of this study was to compare the H. pylori infection frequency in diabetic and non-diabetic patients.Methods: This case-control study was done at Al-Tibri Medical College and Hospital from May 2019 to August 2019. After written and informed consent, patients between 18-75 years with epigastric burning, dyspepsia, regurgitation were included and with history of eradication therapy, antibiotic or NSAID use in the last 6 months or surgery of upper GI tract months were excluded. Type 2 diabetics were placed in one group and non-diabetic individuals in another. Both groups were compared for presence of H. pylori infection. Data was analysed using SPSS. Demographic variables included age, gender and status of H. pylori infection. Quantitative data was expressed as frequency and percentages. Chi-square test was applied to test for significance keeping p-value of <0.05 statistically significant.Results: From 480 patients, 355 patients showed positive H. pylori, among them 282 were diabetic and 73 non-diabetic (p-value <0.001). Amongst the 355 diabetics, 55% were male Among 73 non-diabetics, 64% were male. All the patients in the study had dyspeptic symptoms and complained of dyspepsia, epigastric burning and regurgitation.Conclusions: A substantial relationship between H. pylori infection among type 2 diabetes mellitus patients was observed compared to non-diabetics. As a result, diabetic patients having active dyspeptic symptoms should undergo further confirmatory tests for diagnosing H. pylori infection.

scholarly journals Effects of posterior capsule stretch on adhesive capsulitis.

2019 ◽  
Vol 26 (08) ◽  
pp. 1272-1277
Author(s):  
Madiha Maryam ◽  
Muhammad Kashif ◽  
Abdul Ghafoor Sajjad ◽  
Razia Rizwan ◽  
Sehrish Ali ◽  
...  
Keyword(s):  
Internal Rotation ◽  
Manual Therapy ◽  
Functional Disability ◽  
Adhesive Capsulitis ◽  
Mean Value ◽  
Control Group ◽  
P Value ◽  
Significant Difference ◽  
Group A ◽  
Group B

To compare the effect of posterior capsular stretch on pain, ROM and functional disability in Adhesive Capsulitis. Study Design: Experimental, Randomized Control Trail. Setting: Department of Physiotherapy, Capital Development Authority Hospital Islamabad. Period: October 2015 to March 2016. Materials and Methods: Forty female patients having aged between 40 to 70 years with freezing and frozen stage of adhesive capsulitis were screened out. Adhesive capsulitis secondary to cervical Spondylosis, osteoporosis, direct trauma and any inflammation were excluded from the study. Subjects were randomly placed into two groups lottery method, the experimental group having 19 subjects received posterior capsular stretch along with conventional manual therapy and electrotherapy  whereas the control group had 21 subjects and they were given manual therapy and electrotherapy alone. The Numeric Pain Rating Scale, Shoulder Pain and Disability Index, and Range of Motion of shoulder joint were used as outcome measures. All the patients were assessed at baseline before intervention and at the completion of 6 weeks of treatment. Data was analyzed using SPSS version 20. Results: Abduction, Internal Rotation and disability show significant result. The abduction mean value of Group A was 115.00±22.023and of the Group B was 81.74±20.653 with p value was P<05. The internal rotation mean value of Group A was 70.71±12.776 and for the Group B was 60.32±8.699 and having p value P<05. The SPADI mean value of Group A was 51.76±22.043 and for the Group B was 24.24±7.287 having p value P<05. The NPRS and external rotation showed non-significant difference. Conclusion: It is concluded that posterior capsular stretch along with mobilization is more effective in treating ROM and functional disability.

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