TEM Sample Prep Tool Matching—DualBeam FIB Cut Look and Measure Monitoring for Process Control and Development in a 300 mm IC Fab

Author(s):  
Jangbae Jeon

Abstract This work presents a novel method of continuous improvement for faster, better and cheaper TEM sample preparation using Cut Look and Measure (CLM). The improvement of the process is executed by operational monitoring of daily beam conditions, end products, bulk thickness control, recipe usage and tool running time. This process produces a consequent decrease in rework rate and process time. In addition, it also increases throughput with better quality TEM samples.

2017 ◽  
pp. 94-101
Author(s):  
Saut Pruba

Quality is a term that has diflferent meanings to different people. Quality set out in this paper are the features and characteristics of the total of a product or service associated with its ability to satisfij the needs of the visible or disguised. The quality of the environment requires an establishment of TQM because quality can not be examined only in a product. In this paper also discussed the concept of the seven TQM: continuous improvement, Six Sigma, employee empowerment, benchmarking, just in time, the concept of Taguchi TQM techniques and knowledge. TQM is the seventh technique check sheet, scatter diagrams, cause-effect diagrams, Pareto charts, flow charts, histograms, and statistical process control.


2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Huiyan Jiang ◽  
Baochun He ◽  
Zhiyuan Ma ◽  
Mao Zong ◽  
Xiangrong Zhou ◽  
...  

A novel method based on Snakes Model and GrowCut algorithm is proposed to segment liver region in abdominal CT images. First, according to the traditional GrowCut method, a pretreatment process using K-means algorithm is conducted to reduce the running time. Then, the segmentation result of our improved GrowCut approach is used as an initial contour for the future precise segmentation based on Snakes model. At last, several experiments are carried out to demonstrate the performance of our proposed approach and some comparisons are conducted between the traditional GrowCut algorithm. Experimental results show that the improved approach not only has a better robustness and precision but also is more efficient than the traditional GrowCut method.


2021 ◽  
Vol 100 (8) ◽  
pp. 869-874
Author(s):  
Olga M. Zhurba ◽  
Anton N. Alekseenko ◽  
Salim F. Shayakhmetov

Introduction. To assess the impact of the toxicants vinyl chloride (VC) and 1,2-dichloroethane (DCE) on humans, personalized biomonitoring of thiodiacetic acid (TDAA) is of most significant importance. Determination of TDAA in urine was carried out using the method of gas chromatography-mass spectrometry GC-MS. Materials and methods. Sample preparation consists of the analyte’s esterification in a biological matrix with methyl alcohol (with 10% boron trifluoride), extraction of the derivative by liquid extraction with ethyl acetate. We used an Agilent 7890A gas chromatograph with an HP-5MS capillary column and a mass-selective detector. TDAA was identified in the form of a dimethyl ester on a mass chromatogram according to the retention time and the ratio of the intensities of the registered ions. Results. To determine the rational parameters of the sample preparation process for the determination of TDAA in urine studies were carried out under the method of planning the experiment, which makes it possible to obtain the most accurate mathematical description of the processes. Optimization of the conditions for esterification of TDAA was carried out using mathematical planning, varying the temperature, process time, and the nature of the catalyst (BF3 or H2SO4). The scheduling matrix included eight experiments; the degree of conversion of TDAA served as an optimization parameter. Interpretation of the model showed that temperature makes more contribution to the formation of the degree of conversion than the processing time. The nature of the catalyst does not affect the degree of conversion. Conclusion. A mathematical model developed for optimizing the conditions for sample preparation of the biomarker of exposure to VC (TDAA) in urine, showed the contribution of three factors (reaction temperature, reaction time, catalyst nature) to the conversion rate, of which the reaction temperature makes the greatest contribution to the choice of optimal esterification conditions. The nature of the catalyst (BF3 or H2SO4) does not affect the conversion rate.


Author(s):  
Jagdish Patel ◽  
Komal Murtadak ◽  
Sayali Deore ◽  
Vaishnavi Thorat

They say that companies that do not understand the importance of Analyzation are less likely to survive in the modern economy. Your data is your most valuable asset. Data management is important because the data your organization create is a very valuable resource. The last thing you want to do is spend time and resources collecting data and business intelligence, only to lose or misplace that information. In that case, you would then have to spend time and resources again to get that same business intelligence you already had. However, only well prepared and analyzed data leads to process knowledge and finally, to process control and continuous improvement. Thus, a robust and efficient data analytics strategy is one of the most valuable concepts for the process industry.


2020 ◽  
Vol 70 (2) ◽  
pp. 165-177
Author(s):  
Timothy M. Young ◽  
Patricia K. Lebow ◽  
Stan Lebow ◽  
Adam Taylor

Abstract An approach for implementing statistical process control and other statistical methods as a cost-savings measure in the treated-wood industries is outlined. The purpose of the study is to use industry data to improve understanding of the application of continuous improvement methods. Variation in wood treatment is a cost when higher-than-necessary chemical retention targets are required to meet specifications. The data for this study were obtained in confidence from the American Lumber Standard Committee and were paired, normalized assay retentions for charges inspected by both the treating facility and auditing agencies. Capability analyses were developed from this data for three use categories established by the American Wood Protection Association (AWPA), including UC3B (above ground, exterior), UC4A (ground contact, freshwater, general use), and UC4B (ground contact, freshwater, critical structures, or high decay hazard zones). Agency and industry data indicate that between 4.45 and 9.82 percent of the charges were below the lower confidence limit of the passing standard (LCLAWPA), depending on use category. A Taguchi loss function (TLF), which is quadratic based and decomposes the monetary loss into shift and variation components, was developed to estimate the additional cost due to process variation. For example, if a treatment input cost of $1.00/ft3 is assumed for UC3B, reducing the variation in total retention allows lowering treatment targets, e.g., 1.45 to 1.38, reducing costs to $0.76/ft3. The study provides some important continuous improvement tools for this industry such as control charts, Cpk, Cpm capability indices, and the one-sided TLF.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Nathan LaPierre ◽  
Mohammed Alser ◽  
Eleazar Eskin ◽  
David Koslicki ◽  
Serghei Mangul

Abstract Metagenomic profiling, predicting the presence and relative abundances of microbes in a sample, is a critical first step in microbiome analysis. Alignment-based approaches are often considered accurate yet computationally infeasible. Here, we present a novel method, Metalign, that performs efficient and accurate alignment-based metagenomic profiling. We use a novel containment min hash approach to pre-filter the reference database prior to alignment and then process both uniquely aligned and multi-aligned reads to produce accurate abundance estimates. In performance evaluations on both real and simulated datasets, Metalign is the only method evaluated that maintained high performance and competitive running time across all datasets.


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