scholarly journals A Case Report on a Pancreatic Enigma: Metastatic Solid Pseudopapillary Neoplasm

Author(s):  
Ashna S Pal ◽  
Ashna S Pal ◽  
Fadl H Veerankutty ◽  
Sidharth Chacko ◽  
Vipin IS ◽  
...  

Introduction: Solid pseudopapillary neoplasm is a unique enigmatic disease typically affecting young females. Being a low-grade neoplasm surgical resection is often curative. Rare cases (5-15%) present with distant metastasis. Only 2% has lymph nodal metastasis. This is a case report of metastatic SPN with both visceral and lymph nodal involvement. The work has been reported in line with the SCARE criteria. Case Presentation: The authors present a case of metastatic SPN in an 18-year-old female who came with an abdominal lump. Contrast enhanced CT abdomen findings were in favour of huge SPN arising from pancreatic tail. The prime concern was the coexistence of bilobar liver metastasis predominantly involving right lobe. The complexity of surgical resection along with metastatectomy in a young female was herculean. This clinical dilemma was tackled with staged resection. Conclusion: Even in metastatic SPN a reasonable survival can be achieved by surgical debulking. We emphasize the importance of aggressive approach in operable metastatic SPN.

2018 ◽  
Vol 1 (2) ◽  
pp. 58-62
Author(s):  
Nasim Sana ◽  
◽  
Shahzad Noman ◽  
Mistry Akbar ◽  
Chundriger Qurratulain ◽  
...  

Solid Pseudopapillary Neoplasm (SPN) of the pancreas is a rare neoplasm that typically affects young females. It is a low-grade malignant tumor which is quite commonly misdiagnosed as pancreatic pseudo-cyst. We report a case of SPN in a young female who presented with epigastric pain. Computerized Tomographic (CT) scan of pancreas revealed well demarcated lesion in the head of pancreas. She underwent Whipple procedure. Histopathology confirmed the diagnosis. She did not need any further treatment.


2009 ◽  
Vol 62 (11-12) ◽  
pp. 583-586 ◽  
Author(s):  
Dejan Cvjetkovic ◽  
Mirjana Aleksic-Djordjevic ◽  
Jovana Jovanovic ◽  
Ivana Hrnjakovic-Cvjetkovic ◽  
Sandra Stefan-Mikic ◽  
...  

Introduction. Bacteria from genus Enterococcus may cause infections mostly in those who are immunocompromised and those who underwent endoscopic or surgical procedures. Endocarditis is caused by enterococci in 5-10% of cases. Its clinical presentation does not differ from endocarditis of other bacterial origin. Previous susceptibility testing is needed for appropriate choice of antibiotics against enterococci. The treatment recommendations for enterococcal endocarditis were given by American Heart Association recently. Case report. A case of enterococcal endocarditis in a young female person hospitalised at Clinic for infectious diseases was reviewed. The disease was diagnosed during an extensive diagnostic procedure. Multiply repeated echocardiographic examination helped to find out bacterial vegetations on the mitral valve. Enterococcus species was isolated from several blood cultures. Despite powerful antibiotic treatment, the additional valvular replacement had to be done. Discussion. A case of enerococcal endocarditis in a young female person was reviewed. The right diagnosis was based on a thorough clinical examination in cooperation with cardiologists using repeated transthoracic and transesophageal echocardiography. Echocardiography, even if it is transesophageal, has limited sensitivity and specify, so it is sometimes necessary to be repeated for several times in diagnosing endocarditis. The source of endocarditis was not identified. The combined antimicrobial and surgical treatment led to the complete recovery of patient. Conclusion. Enterococcal endocarditis rarely occurrs in young females. Infective disease specialists sometimes face enterococcal endocarditis in their practice, mostly when they have to cope with fever of unknown origin. An appropriate approach to such conditions includes careful search for heart valve changes by repeated echocardiographic finding, if necessary.


1997 ◽  
Vol 111 (12) ◽  
pp. 1171-1173 ◽  
Author(s):  
Patrick M. Gardner ◽  
Jeffrey M. Jentzen ◽  
Richard A. Komorowski ◽  
Joseph M. Harb

AbstractNeurogenic tumours of the larynx are unusual, with approximately 115 cases reported in the literature to date. Most of these lesions are benign, solitary submucosal nodules which present with hoarseness and are amenable to surgical resection. We present a case of a large pedunculated schwannoma arising in the aryepiglottic fold associated with sudden asphyxial death in an otherwise healthy young female.


2004 ◽  
Vol 132 (11-12) ◽  
pp. 431-434 ◽  
Author(s):  
Aleksandar Karamarkovic ◽  
Marjan Micev ◽  
Djordje Culafic ◽  
Nada Popovic ◽  
Vladimir Djukic

Solid-cystic-pseudopapillary tumor (SCPT) of the pancreas, described by Frantz (1959), is a very rare clinical pathologic entity with relatively low grade malignant potential. The tumor is more frequent in the body and tail of the pancreas. The majority of patients are young females. About 60% of patients are asymptomatic. Complications such as rupture, bleeding or secondary infections are rare. Metastases of the tumor and local recurrence after surgical treatment are also rare. Prognosis is excellent after complete surgical removal. It is difficult to make a preoperative diagnosis of pancreatic SCPT. The exact diagnosis is based on histological findings. Differential diagnosis should consider pancreatoblastoma, non neoplastic cysts, pancreatic pseudo-cysts and hydatid cyst. This is a case report of 39-year old woman who was admitted to our institution with abdominal discomfort and palpable abdominal mass in the upper abdomen. US and CT scan revealed round neoformation of 60 mm in diameter located in the body of the pancreas. Imaging features were not specific enough to allow for precise diagnosis. Curative R0 left spleno-hemipancreatectomy was performed. Histology of the resected specimen revealed solid and cystic-pseudopapillary tumor of the pancreas. The patient was discharged on postoperative day 7 in a good condition. The patient is well 48 months after the operation, with no impairment of pancreatic endocrine or exocrine function.


Author(s):  
Nuno Jorge Lamas ◽  
Carolina Fleming ◽  
Bruno Fernandes ◽  
José Ricardo Brandão ◽  
Mariana Marques Oliveira

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 2135
Author(s):  
Ravi Ranjan Pradhan ◽  
Ajay Kumar Yadav ◽  
Sant Yadav ◽  
Prashant Kumar Gupta

Stroke in a young female is rare but, when it occurs, has a serious economic, and mental burden to the patient, and family members. Peripartum cardiomyopathy (PPCM) is one of the rare causes of stroke in young females.  We report a case of a 20-year-old female with PPCM complicated by cardioembolic stroke. The patient was started on long-term anticoagulation, and her heart failure regimen was optimized upon discharge. Anticoagulation therapy in cardioembolic stroke prevents further complications.


2020 ◽  
Vol 7 (2) ◽  
pp. 1-3
Author(s):  
Martin Kukucka ◽  

Solid pseudopapillary neoplasm of the pancreas is a rare pancreatic tumor with low malignant potential, typically affecting young women. In literature this tumor may be referred to as Frantz tumor, solid tumor, cystic tumor, papillary-cystic tumor or solid pseudopapillary tumor. According to the current WHO classification from 2010 these tumors are considered low-grade malignant epithelial tumors of pancreas. In this case report we present a case of 19-years old women with cystic lesion located in left hypogastrium. After thorough evaluation and subsequent multidisciplinary consultation, the patient was indicated to radical resection of the lesion. Final histological evaluation of the surgical specimen revealed the diagnosis of solid-pseudopapillary neoplasm.


Author(s):  
F Keen ◽  
F Iqbal ◽  
P Owen ◽  
A Christian ◽  
N Kumar ◽  
...  

Summary We present a 60-year-old woman who underwent successful surgical resection (partial pancreatectomy) for a low grade non-functioning pancreatic neuroendocrine tumour (pNET), with no biochemical or radiological features of recurrence on follow-up visits for 5 years. Fourteen years after the initial surgery, she developed spontaneous severe hypoglycaemic episodes which required hospitalisation, with subsequent investigations confirming the diagnosis of a metastatic insulin-secreting pNET (insulinoma). Medical management of her severe spontaneous hypoglycaemic episodes remained challenging, despite optimum use of diazoxide and somatostatin analogue therapy. Based on a discussion at the regional neuroendocrine tumour multidisciplinary team meeting, she underwent an elective hepatic trans-arterial embolization which was unfortunately unsuccessful. She ended up requiring an emergency right hemihepatectomy and left retroperitoneal mass resection which finally stabilised her clinical condition. Learning points: Ours is only the seventh case report of a previously benign pNET presenting as a functional insulin secreting metastatic tumour. However, it is the first case report, in which the metastatic functional pNET presented after such a long hiatus (14 years). There is currently no clear consensus regarding the length of follow-up of non-functional pNET which are deemed cured post-surgical resection, with most guidelines advocating a median follow up of 5 years (1). The delayed presentation in our case suggests additional considerations should be made regarding optimal post-operative surveillance duration based on the age of the patient, location of the tumour, lymph node spread and Ki-67 index. Hepatic artery embolization and/or partial hepatectomy remains a treatment option for pNET patients with significant hepatic metastasis.


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