scholarly journals Pulmonary Artery Sarcoma Diagnosed by Transbronchial Endosonographic (EBUS-TBNA) Approach

2020 ◽  
pp. 1-4
Author(s):  
Grigoris Sratakos ◽  
Konstantina Frangia-Tsivou ◽  
Abir Alsaid ◽  
Eleni Karetsi ◽  
Evangelia Koukaki ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Clinical Manifestations ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Endobronchial Ultrasound ◽  
Vascular Tumors ◽  
Surgical Biopsy ◽  
Transbronchial Needle Aspiration ◽  
Curative Intent ◽  
Pulmonary Artery Sarcoma

Background: Pulmonary Artery Sarcomas are the rarest and the most aggressive vascular tumors. Their accurate diagnosis is challenging due to the lack of specific symptoms and clinical manifestations and they are often initially misdiagnosed and managed as chronic pulmonary thromboembolic disease until an alternate diagnosis is suspected based on the lack of response to anticoagulants. Proper management is thus often delayed until histological confirmation. Moreover, the lack of consensus regarding their diagnosis and treatment further contributes to their reported high mortality [1]. Case Presentation: We present the case of a 34-year-old male, nonsmoker, who presented with hemoptysis, fatigue and dyspnea on exertion 3 months prior to admission. His chest x-ray showed enlargement of the left hilum and chest CT revealed a large intraluminal low attenuation filling defect at the level of the left PA. Chest MRI confirmed the presence of a large endovascular tumor of the left PA. Before referring the patient for surgical biopsy, he underwent bronchoscopy during which the vascular tumor was successfully located, observed and sampled by endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA). Tissue biopsy through EBUS-TBNA revealed an intimal sarcoma of the PA. The patient was subsequently referred for surgical excision with curative intent. Conclusion: Bronchoscopy and EBUS-TBNA may safely and accurately diagnose even rare pathologies of the mediastinal vasculature adjacent to the airways through transbronchial approach.

Pulmonary Artery Sarcoma Diagnosed by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

2013 ◽  
Vol 96 (2) ◽  
pp. e33-e35 ◽  
Author(s):  
Masato Shingyoji ◽  
Dai Ikebe ◽  
Meiji Itakura ◽  
Takahiro Nakajima ◽  
Makiko Itami ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Needle Aspiration ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Transbronchial Needle Aspiration ◽  
Pulmonary Artery Sarcoma

scholarly journals A Case Report of Primary Pulmonary Artery Intimal Sarcoma

2021 ◽  
Author(s):  
Xiaofang Bai ◽  
Litao Ruan
Keyword(s):  
Pulmonary Embolism ◽  
Pulmonary Artery ◽  
Surgical Excision ◽  
Final Diagnosis ◽  
Initial Symptom ◽  
Pulmonary Artery Sarcoma ◽  
Intimal Sarcoma ◽  
Delayed Treatment ◽  
Primary Pulmonary Artery Sarcoma ◽  
Relationship Of

Abstract Background: Pulmonary artery intimal sarcoma(PAS) is a very rare disease, the prevalence of it is about 0.001%-0.003%1. PAS is often misdiagnosed as acute or chronic pulmonary thromboembolism due to its clinical presentation and radiological findings. Thus early diagnosis is very crucial and may improve patient outcome.Case presentation: Here we report a case in a Chinese male which the symptom as presentation was episodes of shortness of breath. Transthoracic echocardiography showed a solid mass in the pulmonary valve orifice, which was demonstrated to be a pulmonary artery intimal sarcoma diagnosed by histopathology2. In this case the initial differential diagnosis included pulmonary embolism. Because the initial symptom of primary pulmonary artery sarcoma is extremely similiar to the pulmonary embolism. Half of them may be misdiagnosed as pulmonary embolism. Imaging studies are very helpful. Ultrasound and CT are the best due to their resolution and ability to assess the relationship of the mass with the surrounding structures. The final diagnosis is mostly made after surgical excision and this is the most effective treatment. At the same time, radiotherapy and chemotherapy after surgery is also a adjuvant treatment3.Conclusion: We report a very rare case of pulmonary artery intimal sarcoma, due to late diagnosis and delayed treatment in this case, the patient display a poor prognostic. Early diagnosis and right treatment can improve the prognosis of PAS and optimize overall health.

scholarly journals Differential diagnosis of granulomatous lung disease: clues and pitfalls

2017 ◽  
Vol 26 (145) ◽  
pp. 170012 ◽  
Author(s):  
Shinichiro Ohshimo ◽  
Josune Guzman ◽  
Ulrich Costabel ◽  
Francesco Bonella
Keyword(s):  
Differential Diagnosis ◽  
Lung Diseases ◽  
Granulomatosis With Polyangiitis ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Needle Aspiration ◽  
Endobronchial Ultrasound ◽  
Eosinophilic Granulomatosis With Polyangiitis ◽  
High Resolution Computed Tomography ◽  
Transbronchial Needle Aspiration

Granulomatous lung diseases are a heterogeneous group of disorders that have a wide spectrum of pathologies with variable clinical manifestations and outcomes. Precise clinical evaluation, laboratory testing, pulmonary function testing, radiological imaging including high-resolution computed tomography and often histopathological assessment contribute to make a confident diagnosis of granulomatous lung diseases. Differential diagnosis is challenging, and includes both infectious (mycobacteria and fungi) and noninfectious lung diseases (sarcoidosis, necrotising sarcoid granulomatosis, hypersensitivity pneumonitis, hot tub lung, berylliosis, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis, rheumatoid nodules, talc granulomatosis, Langerhans cell histiocytosis and bronchocentric granulomatosis). Bronchoalveolar lavage, endobronchial ultrasound-guided transbronchial needle aspiration, transbronchial cryobiopsy, positron emission tomography and genetic evaluation are potential candidates to improve the diagnostic accuracy for granulomatous lung diseases. As granuloma alone is a nonspecific histopathological finding, the multidisciplinary approach is important for a confident diagnosis.

The Techniques of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

2011 ◽  
Vol 6 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Takahiro Nakajima ◽  
Kazuhiro Yasufuku
Keyword(s):  
Lymph Node ◽  
Diagnostic Yield ◽  
Mediastinal Lymph Node ◽  
Needle Aspiration ◽  
Endobronchial Ultrasound ◽  
Lymph Node Staging ◽  
Ultrasound Guided ◽  
Surgical Biopsy ◽  
Transbronchial Needle Aspiration ◽  
High Diagnostic Yield

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive modality for mediastinal lymph node staging in lung cancer patients as well as for the diagnosis of mediastinal and hilar adenopathy. The high diagnostic yield of EBUS-TBNA for lymph node staging has been shown in systematic reviews and meta-analysis. It has attracted physicians and surgeons as an alternative modality to surgical biopsy for the assessment of patients with enlarged mediastinal and/or hilar lymph nodes. Cell blocks obtained by EBUS-TBNA can be applicable not only for pathologic diagnosis but also for further investigations such as immunohistochemistry and fluorescence in situ hybridization. In addition, samples obtained by EBUS-TBNA can also be used for molecular analysis. Unlike regular bronchoscopy, EBUS-TBNA uses the convex probe EBUS with an ultrasound probe on the tip of a flexible bronchoscope. It is important for the bronchoscopist to fully understand the mediastinal anatomy and be able to correlate it with the ultrasound images for a successful EBUS-TBNA. The dedicated transbronchial needle used for EBUS-TBNA is somewhat different from an ordinary transbronchial biopsy forceps. Training is mandatory for achieving high diagnostic yield without complications. The learning curve of EBUS-TBNA is different from each physician, and continuous training program will be needed for impartiality. This article explains the detailed techniques of EBUS-TBNA to master this innovative procedure.

scholarly journals Pulmonary artery tumour-embolism diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration

2011 ◽  
Vol 38 (2) ◽  
pp. 477-479 ◽  
Author(s):  
A. L. Blanc ◽  
C. Jardin ◽  
J. B. Faivre ◽  
O. Le Rouzic ◽  
C. Do Cao ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Needle Aspiration ◽  
Endobronchial Ultrasound ◽  
Ultrasound Guided ◽  
Transbronchial Needle Aspiration

scholarly journals Rapidly involuting congenital hemangioma associated with Kasabach-Merritt Syndrome

2021 ◽  
Vol 4 (1) ◽  
pp. 050-052
Author(s):  
Ballona Rosalia ◽  
Zevallos Jean ◽  
Núñez Jeanette
Keyword(s):  
Surgical Excision ◽  
Vascular Tumor ◽  
Vascular Tumors ◽  
Histopathological Study ◽  
First Year ◽  
Coagulation Disorder ◽  
Tufted Angioma ◽  
First Year Of Life ◽  
Congenital Hemangioma ◽  
Rapidly Involuting Congenital Hemangioma

Background: Rapidly involuting congenital hemangioma (RICH) is a rare vascular tumor that is present at birth and involutes during the first year of life. Kasabach-Merritt syndrome (KMS) is a complication of some vascular tumors such as kaposiform hemangioendothelioma and tufted angioma associated with thrombocytopenia and coagulopathy. Results: The case of a 2-month-old infant with a diagnosis of RICH with thrombocytopenia and coagulation disorder, successfully treated with surgical excision without complications or recurrence is presented. Conclusion: The association between RICH and KMS is rare. Histopathological study, immunohistochemistry and ultrasound findings are important for the diagnosis. Brief summary: This report covers the rare association between rapidly involuting congenital hemangioma and Kasabach-Merritt syndrome in a 2-months-old female infant.

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