scholarly journals Co-Occurrence of Submucosal Schwannoma and Low-Grade Mucinous Neoplasm in the Appendix, a Clinical Conundrum : A Case Report

2020 ◽  
pp. 1-4
Author(s):  
Akitoshi  Nankaku ◽  
Akitoshi  Nankaku ◽  
Haruhiko Sugimura ◽  
Harutaka Inoue ◽  
Naoki Teratani ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Epigastric Pain ◽  
Relevant Literature ◽  
Ileocecal Resection ◽  
Low Grade ◽  
Clinical Images ◽  
Appendiceal Tumor ◽  
Mucinous Neoplasm ◽  
Radiological Images ◽  
Laparoscopic Ileocecal Resection

Two and more types of tumors rarely occur in the appendix, a constrained space of the human body. We experienced a rare co-occurrence of schwannoma and low-grade mucinous neoplasm (LAMN) in the appendix and obtained a lesson to scrutinize the radiological images in the follow-up period. A computer tomography (CT) performed for surveillance of bile duct stone of a 68-year-old man incidentally detected the appendiceal tumor, which characteristics were not clear at that time, 1-year before admission because of epigastric pain due to acute cholecystitis. CT showed enlargement of tumor in the appendix, and laparoscopic ileocecal resection and cholecystectomy were performed under the diagnosis of acute cholecystectomy and appendiceal tumor. Histopathological examination revealed two types of appendiceal tumors, schwannoma and low-grade appendiceal neoplasm. To the best of our knowledge, co-occurrence of schwannoma and LAMN has never been reported and this complicated our interpretation of clinical images during the course. We report a clinical lesson in handling this rare combination of tumors in the appendix with the relevant literature.

scholarly journals A Case of Colonic Intussusception Associated with a Low-Grade Appendiceal Mucinous Neoplasm Resection in a Laparoscopic Ileocecal Resection

2016 ◽  
Vol 69 (6) ◽  
pp. 299-303
Author(s):  
Yosuke Shida ◽  
Satoru Yamaguchi ◽  
Keisuke Ihara ◽  
Hideo Ogata ◽  
Yasushi Domeki ◽  
...  
Keyword(s):  
Ileocecal Resection ◽  
Low Grade ◽  
Mucinous Neoplasm ◽  
Laparoscopic Ileocecal Resection

scholarly journals A case of low grade appendiceal mucinous neoplasm performed with laparoscopic ileocecal resection due to intussusception

2020 ◽  
Vol 28 (2) ◽  
pp. 60-62
Author(s):  
Hiroaki Shidei ◽  
Teppei Kono ◽  
Rie Imaizumi ◽  
Taro Koike ◽  
Hideyuki Yokokawa ◽  
...  
Keyword(s):  
Ileocecal Resection ◽  
Low Grade ◽  
Mucinous Neoplasm ◽  
Laparoscopic Ileocecal Resection

scholarly journals Emergency laparoscopic ileocecal resection for a low-grade appendiceal mucinous neoplasm with impending rupture: A case report

2021 ◽  
Vol 80 ◽  
pp. 105636
Author(s):  
Yusuke Kitagawa ◽  
Shunsuke Hamasaki ◽  
Toshiko Harada ◽  
Noriyasu Tamura ◽  
Akira Katsuno ◽  
...  
Keyword(s):  
Case Report ◽  
Ileocecal Resection ◽  
Low Grade ◽  
Mucinous Neoplasm ◽  
Impending Rupture ◽  
Laparoscopic Ileocecal Resection

scholarly journals Gastric adenomyoma

2011 ◽  
Vol 68 (6) ◽  
pp. 519-522 ◽  
Author(s):  
Mirko Kerkez ◽  
Nebojsa Lekic ◽  
Djordje Culafic ◽  
Zoran Raznatovic ◽  
Igor Ignjatovic ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Histopathological Examination ◽  
Epigastric Pain ◽  
Case Reports ◽  
Good Condition ◽  
Gastric Antrum ◽  
Low Grade ◽  
Ki 67 ◽  
Adequate Treatment ◽  
Stromal Component

Bacground. Gastric adenomyoma is a rare, hamartomatous tumor localized most frequently in the gastric antrum. Review of the available literature shows only sporadic reports or smaller series. Case reports. We presented a 72-year-old woman admitted due to epigastric pain with dyspeptic difficulties. Biochemical parameters and tumor markers were within the referential limits. Diagnostic procedures (upper endoscopy, endoscopic ultrasonography and computerized tomography) revealed an intramural tumor prominence with intact mucosa on the posterior wall of gastric antrum, not accessible for biopsy. Surgical treatment was performed with total extirpation of the tumor. Histopathological examination verified adenomyoma with focal low grade epithelial dysplasia. Cytologic immunophenotype was consistent with smooth muscle stromal and epithelial tumor (CK7 and CK20 ++ immunophenotype). Stromal component revealed low proliferative index (Ki-67 protein immunoexpression level 3%), and p53 less than 0.1% in both epithelial and stromal components. Following the operation, the patient remained in good condition. Conclusion. Uncertain malignant potential of the gastric adenomyoma in the presented case indicates that timely diagnostics with adequate surgical treatment is crucial for an adequate treatment.

scholarly journals Perforated Goblet Cell Carcinoid of the Appendix

2020 ◽  
Vol 14 (2) ◽  
pp. 354-360
Author(s):  
Kimitoshi Kubo ◽  
Noriko Kimura ◽  
Masato Suzuoki ◽  
Soichiro Matsuda ◽  
Momoko Tsuda ◽  
...  
Keyword(s):  
Lymph Node ◽  
Goblet Cell ◽  
Histopathological Examination ◽  
Lower Abdominal Pain ◽  
Residual Tumor ◽  
Ileocecal Resection ◽  
Goblet Cell Carcinoid ◽  
High Grade Fever ◽  
Perforated Appendix ◽  
Laparoscopic Ileocecal Resection

Goblet cell carcinoid (GCC) of the perforated appendix is rare, and its pathological features and prognosis remain poorly described. A 71-year-old woman was admitted to our hospital for right lower abdominal pain, vomiting, and high-grade fever. She was diagnosed with acute appendicitis and underwent emergency laparoscopic appendectomy. Intraoperative examination revealed an enlarged and perforated appendix. Histopathological examination revealed GCC of the appendix with subserosal invasion. She underwent laparoscopic ileocecal resection with lymph node dissection (D3) following appendectomy. Histopathological findings showed no residual tumor or lymph node metastases. To the best of our knowledge, this report is a valuable addition to the GCC literature, describing a case of GCC of the appendix presenting as perforated appendix.

scholarly journals Placental Complement Activation in Fetal and Neonatal Alloimmune Thrombocytopenia: An Observational Study

2021 ◽  
Vol 22 (13) ◽  
pp. 6763
Author(s):  
Thijs W. de Vos ◽  
Dian Winkelhorst ◽  
Hans J. Baelde ◽  
Kyra L. Dijkstra ◽  
Rianne D. M. van Bergen ◽  
...  
Keyword(s):  
Complement Activation ◽  
Histopathological Examination ◽  
Hla Class I ◽  
Unknown Etiology ◽  
Low Grade ◽  
Classical Pathway ◽  
Newly Diagnosed ◽  
Activation Markers ◽  
Amsterdam Criteria ◽  
Alloimmune Thrombocytopenia

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease that causes thrombocytopenia and a risk of bleeding in the (unborn) child that result from maternal alloantibodies directed against fetal, paternally inherited, human platelet antigens (HPA). It is hypothesized that these alloantibodies can also bind to the placenta, causing placental damage. This study aims to explore signs of antibody-mediated placental damage in FNAIT. We performed a retrospective study that included pregnant women, their newborns, and placentas. It comprised 23 FNAIT cases, of which nine were newly diagnosed (14 samples) and 14 were antenatally treated with intravenous immune globulins (IVIg) (21 samples), and 20 controls, of which 10 had anti-HLA-class I antibodies. Clinical information was collected from medical records. Placental samples were stained for complement activation markers (C1q, C4d, SC5b-9, and mannose-binding lectin) using immunohistochemistry. Histopathology was examined according to the Amsterdam criteria. A higher degree of C4d deposition was present in the newly diagnosed FNAIT cases (10/14 samples), as compared to the IVIg-treated FNAIT cases (2/21 samples, p = 0.002) and anti-HLA-negative controls (3/20 samples, p = 0.006). A histopathological examination showed delayed maturation in four (44%) placentas in the newly diagnosed FNAIT cases, five (36%) in the IVIg-treated FNAIT cases, and one in the controls (NS). C4d deposition at the syncytiotrophoblast was present in combination with low-grade villitis of unknown etiology in three newly diagnosed FNAIT cases that were born SGA. We conclude that a higher degree of classical pathway-induced complement activation is present in placentas from pregnancies with untreated FNAIT. This may affect placental function and fetal growth.

scholarly journals Immunohistochemical detection of procalcitonin in fibrolamellar hepatocellular carcinoma

2021 ◽  
Author(s):  
Kotaro Matsumoto ◽  
Kentaro Kikuchi ◽  
Ayako Hara ◽  
Hiromichi Tsunashima ◽  
Koichi Tsuneyama ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Histopathological Examination ◽  
Epigastric Pain ◽  
Positive Staining ◽  
C Reactive Protein ◽  
Fibrolamellar Hepatocellular Carcinoma ◽  
Tumor Biopsy ◽  
Reactive Protein ◽  
Right Lobe ◽  
The Right

AbstractA 25-year-old woman with fever and epigastric pain was referred to our hospital. Blood examination showed significant liver dysfunction, markedly high C-reactive protein (CRP 19.1 mg/dL) and procalcitonin (48.3 ng/mL) levels. Dynamic computed tomography showed a tumor approximately 120 mm in size in the right lobe of the liver, but with no abscess formation. The patient was hospitalized and started on antibiotics; her CRP level improved, but the procalcitonin level did not decrease. Histopathological examination of the liver tumor biopsy revealed fibrolamellar hepatocellular carcinoma (FLC). Positive staining of the FLC with an anti-procalcitonin antibody suggested the production of procalcitonin.

Dermal fibrosarcoma in a Cashmere goat

2019 ◽  
Vol 47 (03) ◽  
pp. 192-195
Author(s):  
Julia Schoiswohl ◽  
Bianca Lambacher ◽  
Andrea Klang ◽  
Reinhild Krametter-Frötscher
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Connective Tissue ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Low Grade ◽  
Cashmere Goat ◽  
Short Lifespan ◽  
Production Processes

AbstractFibrosarcomas are malignant tumors of the connective tissue, which are characterized by proliferation of fibroblasts. Most of these tumors are localized subcutaneously and cause different symptoms depending on their location. The case report describes a dermal tumor on the outside of the pinna in a 7-year-old female Cashmere goat. The tumor was surgically removed and histopathological examination revealed a low grade fibrosarcoma. Although tumors are rare in ruminants because of the animals’ short lifespan (age of slaughtering in most cases < 24 months) in modern production processes, they should be considered as a differential diagnosis.

Acute lower gastrointestinal bleeding due to low-grade mucinous neoplasm of appendix

2020 ◽  
pp. 1-4
Author(s):  
Murat Karatas ◽  
Cenk Simsek ◽  
Süleyman Gunay ◽  
Baha Zengel ◽  
Gokalp Okut ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Lower Gastrointestinal Bleeding ◽  
Low Grade ◽  
Mucinous Neoplasm

scholarly journals Utility of endoscopic transpapillary pancreatic cyst drainage for intraductal papillary mucinous neoplasm infection

2021 ◽  
Vol 14 (6) ◽  
pp. e242583
Author(s):  
Shunsuke Watanabe ◽  
Masao Toki ◽  
Junji Shibahara ◽  
Tadakazu Hisamatsu
Keyword(s):  
Intraductal Papillary Mucinous Neoplasm ◽  
Cyst Wall ◽  
Pancreatic Cyst ◽  
Epigastric Pain ◽  
Drainage Tube ◽  
Endoscopic Drainage ◽  
Endoscopic Retrograde Pancreatography ◽  
Endoscopic Retrograde ◽  
Mucinous Neoplasm ◽  
Route Of Infection

A 61-year-old woman with intraductal papillary mucinous neoplasm (IPMN) infection, who was treated with antibiotics, developed IPMN reinfection with febrile epigastric pain and was febrile. CT showed that the diameter of the IPMN had grown and hardened, with thickening of the cyst wall. Endoscopic retrograde pancreatography was then performed and a nasopancreatic cyst drainage tube was placed into the cyst. Symptoms and inflammatory findings improved considerably 17 days after endoscopic drainage. Few reports and evidence have been found regarding IPMN infections, and the frequency of onset, route of infection and optimal drainage method remain unknown. This study indicated that endoscopic transpapillary pancreatic cyst drainage was effective and is highly recommended for IPMN infection.

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