Fever Algorithm Development of a Non-invasive Wearable Core Body Temperature Sensor System in Intensive Care Unit Patients

Author(s):  
2017 ◽  
Vol 66 ◽  
pp. 17-20 ◽  
Author(s):  
Savyon Mazgaoker ◽  
Itay Ketko ◽  
Ran Yanovich ◽  
Yuval Heled ◽  
Yoram Epstein

1997 ◽  
Vol 12 (5) ◽  
pp. 261-263 ◽  
Author(s):  
Joseph D. Tobias

Several factors may affect the dosing requirements of neuromuscular blocking agents in pediatric intensive care unit patients. I present a 4 year, 2 month old child who received neuromuscular blockade with cisatracurium and induced hypothermia to control increased intracranial pressure. Induction of hypothermia led to a reduction in cisatracurium infusion requirements. The infusion requirements promptly returned to baseline once the patient's body temperature was allowed to normalize. Priorto induction of hypothermia, the infusion requirements for cisatracurium averaged 3.2 μg/kg/min. During the 48 hours of deliberate hypothermia (core body temperature, 34°C) to control intracranial pressure, cisatracurium infusion requirements averaged 1.7 μg/kg/min. Infusion requirements promptly increased to 3.4 μg/kg/min once body temperature was allowed to return to normal.


2019 ◽  
Vol 91 (2) ◽  
pp. 25-29
Author(s):  
Paweł Podsiadło ◽  
Sylweriusz Kosiński ◽  
Tomasz Darocha ◽  
Katherine Zerebiec ◽  
Przemysław Wolak ◽  
...  

Background: An unintentional drop in core body temperature of trauma victims is associated with increased mortality. Thermoregulation is impaired in these patients, especially when treated with opioids or anesthetics. Careful thermal insulation and active warming are necessary to maintain normothermia. The aim of the study was to assess the equipment and procedures for diagnosing and managing post-traumatic hypothermia in Polish hospitals. Methods: Survey forms regarding equipment and procedures on monitoring of core temperature (Tc) and active warming were distributed to every hospital that admits trauma victims in the Holy Cross Province. Questionnaires were addressed to surgery departments, intensive care units (ICUs) and operating rooms (ORs). Results: 92% of surgery departments did not have equipment to measure core body temperature and 85% did not have equipment to rewarm patients. Every ICU had equipment to measure Tc and 83% had active warming devices. In 50% of ICUs, there were no rewarming protocols based on Tc and the initiation of rewarming was left to the physician’s discretion. In 58% of ORs Tc was not monitored and in 33% the patients were not actively warmed. Conclusions: The majority of surveyed ICUs and ORs are adequately equipped to identify and treat hypothermia, however the criteria for initiating Tc monitoring and rewarming remain unstandardized. Surgery departments are not prepared to manage post-traumatic hypothermia.


2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Aurélien Culver ◽  
Benjamin Coiffard ◽  
François Antonini ◽  
Gary Duclos ◽  
Emmanuelle Hammad ◽  
...  

Abstract Background Circadian clock alterations were poorly reported in trauma patients, although they have a critical role in human physiology. Core body temperature is a clinical variable regulated by the circadian clock. Our objective was to identify the circadian temperature disruption in trauma patients and to determine whether these disruptions were associated with the 28-day mortality rate. Methods A retrospective and observational single-center cohort study was conducted. All adult severe trauma patients admitted to the intensive care unit of Aix Marseille University, North Hospital, from November 2013 to February 2018, were evaluated. The variations of core body temperature for each patient were analyzed between days 2 and 3 after intensive care unit admission. Core body temperature variations were defined by three parameters: mesor, amplitude, and period. A logistic regression model was used to determine the variables influencing these three parameters. A survival analysis was performed assessing the association between core body temperature rhythm disruption and 28-day mortality rate. A post hoc subgroup analysis focused on the patients with head trauma. Results Among the 1584 screened patients, 248 were included in this study. The period differed from 24 h in 177 (71%) patients. The mesor value (°C) was associated with body mass index and ketamine use. Amplitude (°C) was associated with ketamine use only. The 28-day mortality rate was 18%. For all trauma patients, age, body mass index, intracranial hypertension, and amplitude were independent risk factors. The patients with a mesor value < 36.9 °C (p < 0.001) and an amplitude > 0.6 °C (p < 0.001) had a higher 28-day mortality rate. Among the patients with head trauma, mesor and amplitude were identified as independent risk factors (HR = 0.40, 95% CI [0.23–0.70], p = 0.001 and HR = 4.73, 95% CI [1.38–16.22], p = 0.01). Conclusions Our results highlight an association between core body temperature circadian alteration and 28-day mortality rate. This association was more pronounced in the head trauma patients than in the non-head trauma patients. Further studies are needed to show a causal link and consider possible interventions.


Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3315 ◽  
Author(s):  
Jorge Chaglla E. ◽  
Numan Celik ◽  
Wamadeva Balachandran

Continuous and reliable measurements of core body temperature (CBT) are vital for studies on human thermoregulation. Because tympanic membrane directly reflects the temperature of the carotid artery, it is an accurate and non-invasive method to record CBT. However, commercial tympanic thermometers lack portability and continuous measurements. In this study, graphene inks were utilized to increase the accuracy of the temperature measurements from the ear by coating graphene platelets on the lens of an infrared thermopile sensor. The proposed ear-based device was designed by investigating ear canal geometry and developed with 3D printing technology using the Computer-Aided Design (CAD) Software, SolidWorks 2016. It employs an Arduino Pro Mini and a Bluetooth module. The proposed system runs with a 3.7 V, 850 mAh rechargeable lithium-polymer battery that allows long-term, continuous monitoring. Raw data are continuously and wirelessly plotted on a mobile phone app. The test was performed on 10 subjects under resting and exercising in a total period of 25 min. Achieved results were compared with the commercially available Braun Thermoscan, Original Thermopile, and Cosinuss One ear thermometers. It is also comprehended that such system will be useful in personalized medicine as wearable in-ear device with wireless connectivity.


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