scholarly journals A case report pemphigoid gestational case, responding to systemic steroid therapy

2021 ◽  
Vol 2 (2) ◽  
pp. 01-05
Author(s):  
Selma Bakar Dertlioğlu
Keyword(s):  
Case Report ◽  
Mononuclear Cells ◽  
Skin Lesions ◽  
Complement C3 ◽  
Direct Immunofluorescence ◽  
Systemic Steroid ◽  
Pemphigoid Gestationis ◽  
Bullous Dermatosis ◽  
Systemic Steroid Therapy ◽  
Histopathologic Findings

In this case report, a rare case of Pemphigoid Gestationis at 33 weeks’ of gestation is presented and the related literature is briefly reviewed. A 21-year-old at 33 weeks’ of gestation admitted with the complain of itchy skin lesions on the abdomen, arms and legs. Dermatologic examination revealed urticaria papules and plaques in the abdomen, arms and legs, more intensely around the umbilicus, which range from 1-2 cm diameter to 4-5 cm diameter. Papulovesicular lesions and few erosions were observed especially in the hand and foot dorsals. Spongiosis on epidermis, intracellular and subepidermal bullae formation, edema on papillary architecture and inflammatory infiltrate composed of mononuclear cells and eosinophils around the perivascular ares of the upper dermis were seen in histological examination. Direct immunofluorescence of perilesional skin showed linear deposition of complement (C3) along the basement membrane zone. The preliminary diagnosis of pemphigoid gestationis was confirmed by histopathologic findings. Pemphigoid gestationis is a rare autoimmune bullous dermatosis that begins in the second or third trimester of pregnancy. Healing occurs weeks after birth. It occurs more severely in subsequent pregnancies. Its main treatment is systemic steroid and antihistamine administration. A multidisciplinary approach both in dermatological and gynecological terms is required for the diagnosis, treatment and course of the disease.

scholarly journals Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Naoki Matsumoto ◽  
Marie Osada ◽  
Kou Kaneko ◽  
Ken Ohara ◽  
Daito Noguchi ◽  
...  
Keyword(s):  
Hydatidiform Mole ◽  
Vital Signs ◽  
Oral Prednisolone ◽  
Skin Lesions ◽  
Complement C3 ◽  
Entire Body ◽  
Complete Hydatidiform Mole ◽  
Pemphigoid Gestationis ◽  
Spontaneous Expulsion ◽  
Hydatidiform Moles

Pemphigoid gestationis (PG) is a rare, perinatal, autoimmune, and blistering dermatosis. Only few cases of PG involving hydatidiform moles have been reported. Complete hydatidiform moles are usually evacuated by dilatation and curettage. We report a patient with a massive complete hydatidiform mole that underwent spontaneous expulsion; she subsequently developed PG. A 19-year-old unmarried nulligravid woman was referred to our hospital following excessive vaginal bleeding after an uncertain amenorrheal period. The patient presented with preshock vital signs, severe anemia, and a positive urine pregnancy test. Imaging examinations revealed a massive intrauterine mass (19 × 15 × 10 cm), suggesting a complete hydatidiform mole. She was hospitalized and treated with blood transfusion. Sixteen hours after hospitalization, the massive molar mass underwent spontaneous expulsion and bleeding ceased. Three days after the expulsion, she developed pruritic skin lesions including papules, erythemas, and bullae, which spread over her entire body. Skin biopsy revealed PG and subepidermal blister formation and linear complement C3 deposition along the basement membrane zone, and the serum anti-BP180 antibody level was found to be high on measurement. She was effectively treated with 50 mg/day of oral prednisolone. Her skin lesions disappeared, leaving pigmentation.

scholarly journals An unusual case of pemphigus erythematosus

2017 ◽  
Vol 4 (4) ◽  
pp. 14
Author(s):  
Dartri Cahyawari ◽  
Eva K Sutedja ◽  
Unwati Sugiri ◽  
Hendra Gunawan ◽  
Oki Suwarsa
Keyword(s):  
Unusual Case ◽  
Systemic Corticosteroid ◽  
Correct Diagnosis ◽  
Skin Lesions ◽  
Complement C3 ◽  
Direct Immunofluorescence ◽  
Small Plaque ◽  
Pemphigus Erythematosus ◽  
Histopathology Examination ◽  
Careful Assessment

Pemphigus erythematosus is characterized by fragile vesicles or bullae, erosions, crusts, and scales in seborrheic area. There are several forms of atypical lesions such as erythematous papules and plaques, verrucous plaques, pustules, and lichenification. Here, we report an atypical pemphigus erythematosus with erythematous papules, plaques, and pustules skin lesions. A 52-year-old Indonesian man presented with prominent pruritic erythematous macules, papules, plaques on the scalp, trunk, and extremities, and also a pustule for each on the back and right arm. Clinically, the patient was diagnosed as small-plaque parapsoriasis, but histopathology examination on the pustule revealed a subcorneal acantholysis and direct immunofluorescence staining showed immunoglobulin G and complement C3 on the cell surface of keratinocytes. These result suitable for pemphigus erythematosus. The patient was treated with topical and systemic corticosteroid, and there were significant improvements in the skin lesions. Pemphigus erythematosus may present with prominent erythematous papules, plaques, and a few pustules. A careful assessment of the clinical manifestation and histopathological findings enabled us to make a correct diagnosis and succesfully treat the patient.

Tumefactive fibroinflammatory lesion of the frontal sinus

2010 ◽  
Vol 124 (11) ◽  
pp. 1212-1215 ◽  
Author(s):  
C M Philpott ◽  
A R Javer
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Frontal Sinus ◽  
Surgical Intervention ◽  
Systemic Steroid ◽  
Review Of The Literature ◽  
Systemic Steroid Therapy ◽  
History Of ◽  
New Location ◽  
Tumefactive Fibroinflammatory Lesion

AbstractObjective:A 65-year-old man presented with a nine-month history of swelling in the midline of the forehead. After surgical intervention, this lesion was found to be a tumefactive fibroinflammatory lesion of the frontal sinus. This case report and review aims to report this new location for tumefactive fibroinflammatory lesion, and to discuss whether, in retrospect, there would have been alternative options to surgery.Methods:Case report and literature review.Results:Tumefactive fibroinflammatory lesions are rare. Although cases in the sinonasal tract have been described, none involving the frontal sinus have previously been reported. A review of the literature suggests that these lesions have an association with other fibroinflammatory lesions, and may be amenable to systemic steroid therapy.Conclusion:Each case should be managed on its merits, and a biopsy taken followed by subsequent screening for associated fibroinflammatory lesions. In the case of an isolated lesion, a surgical approach is probably favoured in a patient suitable for general anaesthesia.

scholarly journals A Periaortitis Patient Who Succumbed to COVID-19 While Undergoing Systemic Steroid Therapy: A Case Report and Literature Review

2021 ◽  
Vol 22 ◽  
Author(s):  
Ammar Abu Baker ◽  
Qusai Aljarrah ◽  
Mohammad Asim Eyadeh ◽  
Kusai Al-Muqbel ◽  
Mohammed Z. Allouh
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Steroid Therapy ◽  
Systemic Steroid ◽  
Systemic Steroid Therapy

scholarly journals Fulminant amebic colitis in a patient with concomitant cytomegalovirus infection after systemic steroid therapy: A case report

2021 ◽  
Vol 9 (15) ◽  
pp. 3726-3732
Author(s):  
Naoki Shijubou ◽  
Toshiyuki Sumi ◽  
Koki Kamada ◽  
Takeyuki Sawai ◽  
Yuichi Yamada ◽  
...  
Keyword(s):  
Case Report ◽  
Steroid Therapy ◽  
Cytomegalovirus Infection ◽  
Systemic Steroid ◽  
Amebic Colitis ◽  
Systemic Steroid Therapy

scholarly journals Benign Mucous Membrane Pemphigoid: A Case Report

2020 ◽  
Vol 4 (2) ◽  
pp. 34-37
Author(s):  
Nidhi Ojha ◽  
Om Prakash Yadav
Keyword(s):  
Case Report ◽  
Mucous Membrane ◽  
Genetic Factors ◽  
Clinical Symptoms ◽  
External Factors ◽  
Treatment Modalities ◽  
Mucous Membrane Pemphigoid ◽  
Systemic Steroid ◽  
Topical Steroids ◽  
Systemic Steroid Therapy

Benign Mucous Membrane Pemphigoid (MMP) is a vesiculobullous (VB) lesion that affects oral and nasal mucosa, oropharynx, conjunctiva, and genital mucosa. It is considered an autoimmune disease. Autoantibodies are produced due to several external factors or genetic factors. It creates many complications, such as defects in vision, voice alteration (hoarseness), airway obstruction, and dyspareunia. The subepithelial blisters form due to these antibodies. Treatment modalities differ from topical steroids to systemic steroid therapy based on the nature and severity of clinical symptoms.

Bacillary angiomatosis in an HIV seronegative patient on systemic steroid therapy

1996 ◽  
Vol 135 (6) ◽  
pp. 982-987 ◽  
Author(s):  
R.A. SCHWARTZ ◽  
M.A. GALLARDO ◽  
R. KAPILA ◽  
P. GASCON ◽  
J. HERSCU ◽  
...  
Keyword(s):  
Steroid Therapy ◽  
Systemic Steroid ◽  
Bacillary Angiomatosis ◽  
Seronegative Patient ◽  
Systemic Steroid Therapy

Scabies superimposed on skin lesions of adult T-cell leukemia/lymphoma: case report and literature review

2008 ◽  
Vol 47 (11) ◽  
pp. 1168-1171 ◽  
Author(s):  
Rieko Kabashima ◽  
Kenji Kabashima ◽  
Ryosuke Hino ◽  
Takatoshi Shimauchi ◽  
Yoshiki Tokura
Keyword(s):  
Case Report ◽  
T Cell ◽  
Literature Review ◽  
Skin Lesions ◽  
T Cell Leukemia ◽  
Cell Leukemia ◽  
Adult T Cell Leukemia
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